Ezetimibe CAS 163222-33-1 Purity 98.5%~102.0% (HPLC) API High Purity
Ubonelelo lwabavelisi;Umgangatho ophezulu kunye nexabiso loKhuphiswano
Ubonelelo ngezoRhwebo lwe-Ezetimibe (CAS: 163222-33-1) abaPhakathi abaNxulumeneyo:
(S)-(+)-4-Phenyl-2-oxazolidinone CAS: 99395-88-7
(R)-(+)-2-Methyl-CBS-oxazaborolidine CAS: 112022-83-0
4-(4-Fluorobenzoyl) butyric acid CAS: 149437-76-3
4-[[(4-Fluorophenyl)imino]methyl]-phenol CAS: 3382-63-6
N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline CAS: 70627-52-0
(3R,4S) -4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-enye CAS 190595-65- 4
(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone CAS: 189028-93-1
(4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-enye CAS: 189028-95-3
Ezetimibe CAS: 163222-33-1
Igama leMchiza | (3R,4S)-1-(4-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-enye |
Izithethantonye | Ezetimibe |
Inombolo yeCAS | 163222-33-1 |
Inombolo yeCAT | RF-API02 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | C24H21F2NO3 |
Ubunzima beMolekyuli | 409.43 |
Indawo yokunyibilika | 162.0 ~ 166.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kwi-Off-White Powder |
Ukuchongwa | Ngo-IR, HPLC |
Ubunyulu / Indlela yokuHlalutya | 98.5%~102.0% (HPLC) |
Ukujikeleziswa okuthe ngqo | -25.0 ° ~ -30.0 ° |
Ukufuma (KF) | ≤0.50% |
Uthuthu lweSulfated | ≤0.10% |
Iintsimbi ezinzima | ≤0.002% |
I-Enantiomer | ≤0.30% |
UMax omnye.Ukungcola | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Ezetimibe (CAS: 163222-33-1) API |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Ezetimibe (i-CAS: i-163222-33-1) i-cholesterol yokuthutha inhibitor ebophelela kwi-NPC1L1, iphuma kwiklasi yezinto ezisetyenziselwa ukunciphisa amanqanaba e-cholesterol egazini liyeza elinciphisa amanqanaba e-plasma ye-cholesterol.Isebenza ngokunciphisa ukufunxa kwe-cholesterol kumathumbu amancinci.Inokusetyenziswa yodwa xa amanye amayeza okunciphisa i-cholesterol enganyamezelwanga, okanye kunye ne-statins (umzekelo, ezetimibe / simvastatin) xa i-statins yodwa ingalawuli i-cholesterol.I-Ezetimibe ilawulwa ngomlomo yodwa okanye njengepilisi edibeneyo kunye ne-simvastatin okanye i-atorvastatin.I-Ezetimibe yamkelwa kwi-2002 yi-FDA, phantsi kwegama lezorhwebo elithi Zetia.Ivunyiwe ukuba isetyenziswe kwi-EU njenge-Ezetrol kunye namanye amagama orhwebo.Iveliswa ngenkqubo yeekhemikhali ezinamanyathelo amaninzi.