Ezetimibe Intermediate ZT-5 CAS 189028-95-3 Purity ≥98.0% (HPLC) Factory High Quality
Igama leMchiza | (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-enye |
Izithethantonye | Ezetimibe Intermediate ZT-5 |
Inombolo yeCAS | 189028-95-3 |
Inombolo yeCAT | RF-PI146 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C20H20FNO4 |
Ubunzima beMolekyuli | 357.38 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe okanye oMhlophe |
Ubunyulu / Indlela yokuHlalutya | ≥98.0% (HPLC) |
Ukungcola ZT-4 | ≤1.0% |
I-Enantiomer | ≤0.20% |
Ukungacoceki Okukodwa | ≤1.5% |
Ukungcola ngokupheleleyo | ≤2.0% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Ezetimibe (CAS: 163222-33-1) Phakathi |
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we (4S) -3-[(5S) -5- (4-Fluorophenyl) -5-hydroxypentanoyl] -4-phenyl-1,3-oxazolidin-2 -enye (CAS: 189028-95-3) enomgangatho ophezulu.Liphakathi kwe-Ezetimibe (CAS: 163222-33-1)
I-Ezetimibe (i-CAS: i-163222-33-1) ichiza le-ananti-hyperlipidemic elisetyenziselwa ukunciphisa amanqanaba e-cholesterol e-plasma.Kuboniswa njengonyango oluncedisayo ekutyeni ekunciphiseni inqanaba eliphezulu lilonke-C, LDL-C, kunye ne-ApoB kwizigulane ezine-hypercholesterolemia yokuqala (i-heterozygous yentsapho kunye ne-non-familial).Ikwasetyenziselwa unyango oludibeneyo kunye ne-HMG-CoA reductase inhibitors.I-Ezetimibe ayivimbeli i-cholesterol synthesis kwisibindi, okanye inyuse i-bile acid excretion.