IFamciclovir CAS 104227-87-4 Ubunyulu ≥99.0% (HPLC) Factory
Nikeza ngokucoceka okuphezulu, iMveliso yoRhwebo
Igama leMichiza: Famciclovir
CAS: 104227-87-4
Igama leMchiza | IFamciclovir |
Izithethantonye | BRL 42810;2-[2-(2-Amino-9H-purin-9-yl)ethyl]-1,3-propanediol Diacetate |
Inombolo yeCAS | 104227-87-4 |
Inombolo yeCAT | RF-API104 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C14H19N5O4 |
Ubunzima beMolekyuli | 321.34 |
Ukunyibilika | Inyibilika kwiMethanol, iEthanol;Inyibilika kancinane emanzini |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
Ukuchongwa | I-HPLC: Ihambelana noMgangatho |
Ukuchongwa | Ukufunxwa kwe-IR: Ihambelana noMgangatho |
Indawo yokunyibilika | 102.0 ~ 104.0℃ |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.20% |
Iintsimbi ezinzima | ≤10ppm |
IArsenic (As) | ≤1ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
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I-Famciclovir (CAS: 104227-87-4) yi-guanosine analogue antiviral drug esetyenziselwa unyango lwezifo ezahlukeneyo ze-herpesvirus, ngokuqhelekileyo kwi-herpes zoster (shingles), unyango lwe-herpes simplex virus 2 (i-herpes yangasese), i-herpes labialis (izilonda ezibandayo ) kwizigulane ezine-immunocompetent kunye nokunyanzeliswa kweziganeko eziphindaphindiweyo ze-herpes simplex virus 2. Kwakhona kuboniswa unyango lweziganeko eziphindaphindiweyo ze-herpes simplex kwizigulane ze-HIV.Yindlela yeprodrug yepenciclovir ene-bioavailability yomlomo ephuculweyo.I-Famciclovir ithengiswa phantsi kwegama lokurhweba elithi Famvir (Novartis).I-Famciclovir yayinelungelo elilodwa lomenzi wechiza ngo-1983 kwaye yamkelwa ukuba isetyenziswe kwezonyango ngo-1994. Ngo-2007, i-United States Food and Drug Administration yaphumeza inguqulelo yokuqala yegeneric yeFamciclovir.