IFavipiravir CAS 259793-96-9 T-705 Ubunyulu ≥99.0% (HPLC) COVID-19 API Factory High Quality
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Ubonelelo ngezoRhwebo lweFavipiravir kunye nabaPhakathi abaNxulumeneyo:
IFavipiravir CAS 259793-96-9
I-2-Aminopropanediamide CAS 62009-47-6
I-Diethyl Aminomalonate Hydrochloride CAS 13433-00-6
3,6-Dichloropyrazine-2-Carbonitrile CAS 356783-16-9
3,6-Difluoropyrazine-2-Carbonitrile CAS 356783-28-3
I-6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile CAS 356783-31-8
I-6-Bromo-3-Hydroxypyrazine-2-Carboxamide CAS 259793-88-9
I-3-Hydroxypyrazine-2-Carboxamide CAS 55321-99-8
Igama leMchiza | IFavipiravir |
Izithethantonye | T-705;I-6-Fluoro-3-Hydroxy-2-Pyrazinecarboxamide |
Inombolo yeCAS | 259793-96-9 |
Inombolo yeCAT | RF-API18 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | C5H4FN3O2 |
Ubunzima beMolekyuli | 157.1 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kwi-Off-White Powder |
Ukuchongwa kwe-1H-NMR | Iyahambelana nesakhiwo esicetywayo |
Ukuchongwa kwe-HPLC | Ixesha lokugcinwa kwencopho ephambili kulungiselelo lwesampulu kufuneka lihambelane nexesha lokugcinwa kwencopho ephambili kulungiselelo lomgangatho wereferensi. |
Isazisi Mass | I-Mass Spectrum iyahambelana nesakhiwo esicetywayo |
Indawo yokunyibilika | 188.0℃-193.0℃ |
Izinto ezinxulumeneyo (Uhlengahlengiso lweNdawo) | Nakuphi na Ukungcola Okukodwa: ≤0.10% (HPLC) |
Ukungcola ngokupheleleyo: ≤1.0% (HPLC) | |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
Ukufuma (KF) | ≤0.50% |
Intsalela kwi-Ignition | ≤0.10% |
Iintsimbi ezinzima | ≤20ppm |
Intsalela yezinyibilikisi | |
IMethanol | ≤3000ppm |
Isopropanol | ≤5000ppm |
n-Heptane | ≤5000ppm |
I-Ethanol | ≤5000ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-Active Pharmaceutical Ingredient (API);Unyango lwe-COVID-19 |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Favipiravir (T-705) (CAS 259793-96-9) yenye yeekhompawundi ezi-5 ezicetyiswa yi-WHO kuphando lonyango lwe-COVID-19.I-Favipiravir sisithinteli esikhethiweyo se-RNA exhomekeke kwi-RNA polymerase esebenza ngokuchasene neentsholongwane ezininzi ze-RNA, iintsholongwane zomkhuhlane, intsholongwane ye-West Nile, intsholongwane ye-yellow fever, intsholongwane yesifo sonyawo kunye nomlomo kunye nezinye ii-flaviviruses, i-arenaviruses, i-bunyaviruses kunye ne-alphaviruses.I-Favipiravir lichiza elilwa nentsholongwane ebanzi elaye lacinywa nguMlawuli Jikelele we-India (DCGI) kwiveki ephelileyo ukusetyenziswa “kuthintelo olungxamisekileyo” phakathi kwabaguli be-Covid-19.IFavipiravir yaveliswa ekupheleni kweminyaka yoo-1990 yinkampani eyathi kamva yathengwa yifem yaseJapan iFujifilm njengenxalenye yotshintsho lwayo ukusuka kwishishini leefoto ukuya kukhathalelo lwempilo.Emva kokuvavanywa ngokuchasene noluhlu lweentsholongwane, ichiza lamkelwa eJapan ngo-2014 ukuze lisetyenziswe ngokukhawuleza ngokuchasene nobhubhane lomkhuhlane okanye ukunyanga iintlobo ezintsha zomkhuhlane.