Fingolimod Hydrochloride CAS 162359-56-0 Purity ≥99.0% (HPLC) API Factory High Purity
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Igama leMichiza: iFingolimod Hydrochloride
CAS: 162359-56-0
I-Fingolimod Hydrochloride lichiza elivunywe yi-FDA kunyango lwe-Multiple Sclerosis.
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | Fingolimod Hydrochloride |
Izithethantonye | I-Fingolimod HCl;FTY 720 |
Inombolo yeCAS | 162359-56-0 |
Inombolo yeCAT | RF-API39 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C19H34ClNO2 |
Ubunzima beMolekyuli | 343.93 |
Indawo yokunyibilika | 102.0~107.0°C |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kwi-Off-White Powder |
Ukuchongwa | HPLC |
Indawo yokunyibilika | 102.0 ~ 106.0℃ |
Ukunyibilika | Inyibilika ngokupheleleyo emanzini |
Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) |
Ukufuma (KF) | ≤0.50% |
Intsalela kwi-Ignition | ≤0.20% |
Iintsimbi ezinzima | ≤20ppm |
Izinyibilikisi ezishiyekileyo | |
Dichloromethane | ≤0.05% |
I-Ethyl Acetate | ≤0.50% |
I-Ethanol | ≤0.50% |
IMethanol | ≤0.30% |
Toluene | ≤0.089% |
I-THF | ≤0.50% |
I-DMF | ≤0.088% |
Izinto ezizalanayo | |
Ukungacoceki Okukodwa | ≤0.50% |
Ukungcola ngokupheleleyo | ≤1.0% |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi weFingolimod Hydrochloride (CAS: 162359-56-0) kunye nomgangatho ophezulu.
I-Fingolimod Hydrochloride lichiza lokuqala lomlomo kunyango lwe-multiple sclerosis.Iphuhliswe ngempumelelo yinkampani yamayeza i-Novartis, kwaye ivunyiwe ukuba ithengiswe yi-US Food and Drug Administration (FDA).I-Multiple sclerosis sisifo se-neurological esiphazamisayo esinokubangela ukuba isigulane silahlekelwe yingqondo yokulinganisela, ukubonakala kwe-muscle spasms kunye nezinye iziphazamiso zokuhamba.I-Fingolimod Hydrochloride yi-sphingosine-l-phosphate (S1PR) ye-receptor modulator.Emva kwe-phosphorylation, Ibopheleleka kwi-s1P ye-receptor ephezu kwe-lymphocyte, eya kutshintsha ukufuduka kwe-lymphocyte, kwaye ikhuthaze iiseli kwizicubu ze-lymphatic, kwaye ithintele i-lymphocytes ukuba ishiye i-lymphoid tissue kwaye ingene kwi-graft.Ngaloo ndlela, iya kuthintela ezi seli ukuba zingene kwinkqubo ye-nervous central (CNS), efezekisa umphumo we-immunosuppression.