Gemcitabine CAS 95058-81-4 Assay 98.0 ~ 102.0%
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili weGemcitabine (CAS: 95058-81-4) enomgangatho ophezulu.I-Ruifu Chemical inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, inkonzo egqwesileyo, encinci kunye nezixa ezininzi ezikhoyo.Thenga iGemcitabine,Please contact: alvin@ruifuchem.com
| Igama leMchiza | Gemcitabine |
| Izithethantonye | 2'-Deoxy-2',2'-Difluorocytidine;4-Amino-1-[3,3-Difluoro-4-Hydroxy-5-(Hydroxymethyl) oxolan-2-yl]pyrimidin-2-enye;I-dFDC;uGemzar (uLilly);I-LY-188011;dFdCyd;iDDFC;2',2'-Difluoro-2'-deoxycytidine;2',2'-Difluorodeoxycytidine;I-Folfugem;iGemLip;iGemcel;Gamcitabine |
| Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso yeeToni ezi-5 |
| Inombolo yeCAS | 95058-81-4 |
| CAS ezinxulumene | 122111-03-9 |
| Ifomula yeemolekyuli | I-C9H11F2N3O4 |
| Ubunzima beMolekyuli | 263.20 g/mol |
| Indawo yokunyibilika | 217.0 ukuba 222.0℃ |
| Ukuxinana | 1.84±0.10 g/cm3 |
| Inovakalelo | Ubushushu Bubuthathaka |
| Ukunyibilika kwamanzi | Ayinyibiliki ngokupheleleyo emanzini |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Imvelaphi | Shanghai, China |
| Uphawu | Ruifu Chemical |
| Izinto | Iinkcukacha | Iziphumo |
| Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe, ongenavumba | Iyahambelana |
| Cytosine | ≤0.10% | 0.002% |
| α-Isomer | ≤0.10% | 0.01% |
| Ukungacoceki komntu | ≤0.10% | 0.03% |
| Ukungcola ngokupheleleyo | ≤1.00% | 0.10% |
| Amanzi nguKarl Fischer | ≤1.00% | 0.67% |
| Ukujikeleziswa okuthe ngqo | + 68.0 ° ~ + 74.0 ° | + 70,5 ° |
| Iintsimbi ezinzima | ≤10ppm | <10ppm |
| Intsalela kwi-Ignition | ≤0.10% | 0.03% |
| Uvavanyo (Nge-HPLC) | 98.0%~102.0% | 99.9% |
| I-Infrared Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| I-1H NMR Spectrum | Ngokungqinelana noLwakhiwo | Iyahambelana |
| Ukuqukumbela | Imveliso ivavanyiwe kwaye ihambelana neenkcukacha ezinikiweyo | |
Umqulu:Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina isikhongozeli sivaliwe kwaye usigcine kwindawo epholileyo, eyomileyo nengena umoya kakuhle kude nezinto ezingahambelaniyo.Kuphephe ukuchanabeka kwilanga elithe ngqo, ukufuma kunye nobushushu obugqithisileyo.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngomoya, ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
Iikhowudi zoMngcipheko R21 - Zinobungozi xa udibana nolusu
R36/38 - Iyacaphukisa emehlweni kunye nolusu.
I-R46 - Isenokubangela umonakalo wemfuzo onokuzuzwa
I-R62 - Umngcipheko onokubakho wokuphazamiseka kokuchuma
I-R63 - Ingozi enokwenzeka yokwenzakala kumntwana ongekazalwa
INkcazelo yoKhuseleko S25-Kuphephe ukudibana namehlo.
S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
S36/37 -Nxiba iimpahla ezifanelekileyo zokukhusela kunye neeglavu.
S53-Kuphephe ukuvezwa-fumana imiyalelo ekhethekileyo phambi kokusetyenziswa.
Ikhowudi yeHS 2934999091
Ubutyhefu LD10 iv kwiimpuku: 200 mg/m2 (Abbruzzese)
I-Gemcitabine (i-CAS: i-95058-81-4) iyeza le-chemotherapy elisetyenziselwa ukunyanga inani leentlobo zomhlaza.Oku kubandakanya umhlaza webele, umhlaza wemiphunga weseli ongewona mncinci, umhlaza wepancreatic, umhlaza wesinyi, kunye nomhlaza webileri.IGemcitabine iphandwa ukuba isetyenziswe kumhlaza wommizo, kwaye isetyenziswa ngokulinga kwii-lymphomas kunye nezinye iindidi zamathumba.I-Gemcitabine ilawulwa ngumzila we-intravenous, ekubeni i-metabolized kakhulu yi-gastrointestinal tract.
I-Gemcitabine yi-analogue ye-nucleotide, eyinxalenye yeklasi ye-anti-metabolic yamachiza e-anticancer.Isebenza kakhulu kwisigaba se-DNA synthesis, oko kukuthi, isigaba se-S.Ngaphantsi kweemeko ezithile, inokuthintela isigaba se-G1 ukuba siqhubele phambili kwisigaba se-S.Ineempawu ze-anticancer spectrum ebanzi, indlela eyodwa yokusebenza, ubutyhefu obuphantsi, akukho ukumelana nokuwela kwamanye amachiza echemotherapy kwaye akukho tyhefu.I-Chemicalbook, i-gemcitabine, ngoku ivunyiwe ukuba isetyenziswe kumazwe angaphezu kwama-90, iyenza ibe yonyango lokuqala lomhlaza wemiphunga weseli kunye "nomgangatho wegolide" womhlaza wepancreatic.
Kwi-1999, i-CFDA ivume i-gemcitabine yonyango lwe-NSCLC yasekhaya ephezulu okanye ye-metastatic, umhlaza we-pancreatic wengingqi okanye we-metastatic;Ngo-2010, i-CChemicalbookFDA yavuma i-gemcitabine ngokudityaniswa ne-paclitaxel kunyango lomhlaza webele ongachanekanga, oqhelekileyo wasekhaya okanye we-metastatic oye waphinda wavela emva kwe-adjuvant/neoadjuvant chemotherapy.
I-Gemcitabine i-antimetabolite ebanzi kunye ne-deoxycytidine analogue kunye nomsebenzi we-antineoplastic.Ekulawuleni, i-gemcitabine iguqulwa ibe yi-metabolites esebenzayo i-difluorodeoxycytidine diphosphate (dFdCDP) kunye ne-difluorodeoxycytidine triphosphate (dFdCTP) nge-deoxycytidine kinase.I-dFdCTP ikhuphisana ne-deoxycytidine triphosphate (dCTP) kwaye ifakwe kwi-DNA.Oku kutshixa i-DNA polymerase ngaloo ndlela kukhokelela ekuphelisweni kwesigqubuthelo ngexesha lokuphindaphindwa kwe-DNA.Kwelinye icala, i-dFdCDP inqanda i-ribonucleotide reductase, ngaloo ndlela inciphisa ichibi le-deoxynucleotide elikhoyo kwi-DNA synthesis.Ukunciphisa i-intracellular concentration ye-dCTP inokubangela ukufakwa kwe-dFdCTP kwi-DNA.
-
I-Darunavir Ethanolate CAS 635728-49-3 Ubunyulu ≥99...
-
Brigatinib CAS 1197953-54-0 Ubunyulu > 99.0% (HPLC)
-
I-Sofosbuvir CAS 1190307-88-0 Ubunyulu ≥99.0% (HPLC)
-
CAS 361442-04-8 Ubunyulu >99.0% (HPLC) API
-
Revaprazan Hydrochloride CAS 178307-42-1 Assay ...
-
I-Sitagliptin Phosphate Monohydrate CAS 654671-77...