Gliepiride CAS 93479-97-1 Assay 98.0%~102.0% API Factory High Purity

Inkcazelo emfutshane:

Igama leMichiza: Glimepiride

CAS: 93479-97-1

Imbonakalo: Umgubo oMhlophe okanye ophantse wamhlophe

Uvavanyo: 98.0% ~ 102.0%

I-Gliepiride kunyango lwe-Noninsulin-Dependent Type 2 Diabetes Mellitus

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ukubonelela ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leMichiza: Glimepiride
CAS: 93479-97-1
I-Gliepiride kunyango lwe-Noninsulin-Dependent Type 2 Diabetes Mellitus
Umgangatho ophezulu we-API, iMveliso yoRhwebo

Iipropati zeMichiza:

Igama leMchiza	Glimipiride
Izithethantonye	Amaril
Inombolo yeCAS	93479-97-1
Inombolo yeCAT	RF-API24
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C24H34N4O5S
Ubunzima beMolekyuli	490.62
Indawo yokunyibilika	212.2~214.5℃
Imeko yokuthumela ngenqanawa	Phantsi koBubushushu be-Ambient
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe okanye ophantse wamhlophe
Ukuchongwa	I-IR (Ifana noMgangatho)
Izinto ezinxulumeneyo
Cis-Isomer (A)	≤0.80%
ISulfonamide (B)	≤0.40%
Urethane (C)	≤0.10%
3-Isomere (D)	≤0.20%
Nakuphi na Okunye Ukungcola	≤0.10%
Ukungcola ngokupheleleyo	≤0.50%
Ilahleko ekomisweni	≤0.50%
Intsalela kwi-Ignition	≤0.10%
Iintsimbi ezinzima	≤0.001%
Isivavanyi	98.0%~102.0%
Umgangatho woVavanyo	I-European Pharmacopeia (EP);I-United States Pharmacopoeia (USP)
Ukusetyenziswa	I-Active Pharmaceutical ingredient (API)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-Gliepiride (i-CAS: 93479-97-1) enomgangatho ophezulu, isithako esisebenzayo seyeza (API).IGlimipiride lichiza le-antidiabetic elinceda ukulawula amanqanaba eswekile yegazi.I-Glimepiride yinto esebenza ixesha elide, isizukulwana sesithathu se-sulfonylurea esinomsebenzi we-hypoglycemic.

IGlimepiride (igama lokuqala lokurhweba i-Amaryl) lichiza le-sulfonylurea le-antidiabetic elifumaneka ngomlomo ukuya kwixesha elide.Njengazo zonke ii-sulfonylureas, i-glimepiride isebenza njenge-insulin secretagogue.Yehlisa iswekile yegazi ngokuvuselela ukukhutshwa kwe-insulin kwiiseli ze-beta ze-pancreatic kunye nokwandisa uvakalelo lwezicubu ze-peripheral kwi-insulin.I-Gliepiride inokuthi ibophelele kwi-ATP-sensitive potassium i-receptors kwi-pancreatic cell cell, inciphisa ukuqhuba kwe-potassium kwaye ibangele ukuchithwa kwe-membrane.I-Membrane depolarization ivuselela ukungena kwe-calcium ion ngokusebenzisa i-voltage-sensitive calcium channels.Oku kwanda kwi-intracellular calcium ion concentration ibangela ukukhutshwa kwe-insulin.I-Gliepiride isetyenziswa ikakhulu ukunyanga abaguli abanesifo seswekile esi-2 kwaye inokunciphisa amathuba okuba umntu abe neengxaki zohlobo lwesi-2 seswekile.Ichiza lavunywa yi-FDA ngo-1995 kwaye lenziwa yi-Sanofi-Aventis.Inokusetyenziswa kunye nokutya okufanelekileyo kunye nenkqubo yokwenza umthambo kwaye inokusetyenziswa yodwa okanye kunye namanye amayeza okulwa nesifo seswekile xa kuyimfuneko.I-Gliepiride inokusetyenziswa njenge-monotherapy okanye idityaniswe ne-insulin.