I-Guanfacine Hydrochloride I-Guanfacine HCl CAS 29110-48-3 API USP Standard High Purity
Umenzi onobunyulu obuPhezulu kunye noMgangatho oZinzile
Igama leMichiza: iGuanfacine Hydrochloride
Izithethantonye: Guanfacine HCl
CAS: 29110-48-3
I-Guanfacine Hydrochloride yinto ekhethiweyo ye-α2A-adrenoceptor agonist.I-Antihypertensive
Umgangatho ophezulu we-API, iMveliso yoRhwebo
Igama leMchiza | IGuanfacine Hydrochloride |
Izithethantonye | IGuanfacine HCl |
Inombolo yeCAS | 29110-48-3 |
Inombolo yeCAT | RF-API40 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C9H10Cl3N3O |
Ubunzima beMolekyuli | 282.55 |
Indawo yokunyibilika | 211.0 ~ 215.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ukuchongwa | Ukufunxwa kwe-infrared;HPLC |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.10% |
Iintsimbi ezinzima | ≤20ppm |
Isivavanyi | 98.0% ~ 102.0% (HPLC kwisiseko esomisiweyo) |
Ubunyulu beChromatographic | ≥99.0% |
Umgangatho woVavanyo | Umgangatho we-USP |
Ukusetyenziswa | I-Active Pharmaceutical ingredient (API) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi weGuanfacine Hydrochloride (CAS: 29110-48-3) enomgangatho ophezulu.
IGuanfacine hydrochloride esembindini esebenza njenge-adrenoceptor agonist.I-Antihypertensive.I-Guanfacine hydrochloride, i-anti-hypertensive agent, i-agonist ekhethiweyo ye-α2A-adrenoceptor ene-Kd ye-31 nM kwaye ibonisa i-60-fold selectivity phezu kwe-α2B-adrenoceptors.I-Guanfacine yehlisa zombini uxinzelelo lwegazi lwe-systolic kunye ne-diastolic ngokuvula inkqubo ye-nervous central α2A i-norepinephrine autoreceptors, ekhokelela ekunciphiseni ukuphuma kwe-peripheral sympathetic outflow kwaye ngaloo ndlela ukuncipha kwethoni yovelwano lwe-peripheral.Izicelo zonyango ze-guanfacine ziyafana nezo zezinye ezisebenza kwindawo esembindini i-α2-adrenergic agonists kunye ne-methyldopa.Kuye kwasebenza njenge-monotherapy kunyango lwezigulane ezinoxinzelelo lwegazi oluphantsi ukuya phakathi.