I-H-Glu(OBzl)-NCA CAS 3190-71-4 Ubunyulu > 98.0% (HPLC) I-Glatiramer Acetate ePhakathi yoMfanekiso oPhambili

H-Glu(OBzl)-NCA CAS 3190-71-4 Ubunyulu>98.0% (HPLC) Glatiramer Acetate Intermediate

Inkcazelo emfutshane:

I-5-Benzyl L-Glutamate N-Carboxyanhydride

Izithethantonye: H-Glu(OBzl)-NCA

CAS: 3190-71-4

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Mhlophe ukuya kwi-Off-White Powder

IiAmino Acids & Derivatives, Umgangatho ophezulu

Umbindi weGlatiramer Acetate (CAS: 147245-92-9)

Qhagamshelana: UGqr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-5-Benzyl L-Glutamate N-Carboxyanhydride (H-Glu (OBzl)-NCA) (i-CAS: 3190-71-4) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-amino acids kunye nezinto eziphuma kuzo.Sinokubonelela ngeenkonzo zehlabathi, ezincinci kunye nezixa ezininzi ezikhoyo.Ukuba ufuna i-H-Glu(OBzl)-NCA,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	I-5-Benzyl L-Glutamate N-Carboxyanhydride
Izithethantonye	H-Glu(OBzl)-NCA;L-Glu(OBzl)-NCA;(S)-Benzyl 3-(2,5-Dioxooxazolidin-4-yl)propanoate;I-Benzyl (S)-3-(2,5-Dioxooxazolidin-4-yl)propanoate;(4S) -2,5-Dioxo-4-Oxazolidinepropanoic Acid Phenylmethyl Ester;(+)-(S)-Glutamic Acid γ-Benzyl Ester N-Carboxyanhydride;I-L-Glutamic Acid-γ-Benzyll ester N-Carboxyanhydride;L-γ-Benzylglutamic Acid Carboxyanhydride;γ-Benzyl N-carboxy-L-Glutamic Anhydride;I-5-Benzyl Glutamic Acid Ester NCA
Ubume beStokhwe	Ikhona evenkileni
Inombolo yeCAS	3190-71-4
Ifomula yeemolekyuli	C13H13NO5
Ubunzima beMolekyuli	263.25 g/mol
Indawo yokunyibilika	85.0~95.0℃
Ukuxinana	1.293 g/cm3
Refractive Index	1.54
Inovakalelo	Ukungeva kuMoya, Ubushushu abuva
I-COA kunye ne-MSDS	Iyafumaneka
Ukuhlelwa	Amino Acids & Derivatives
Uphawu	Ruifu Chemical

Iinkcukacha:

Izinto	ImiGangatho yokuHlola	Iziphumo
Imbonakalo	Mhlophe ukuya kwi-Off-White Powder	I-Off-White Powder
Iindlela zokuchongwa	HNMR / HPLC	Iyahambelana
Indawo yokunyibilika	85.0~95.0℃	87.3~88.5°C
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)	98.5%
Ukujikeleziswa okuthe ngqo [α]20/D	-14.0° ± 2.0° (C=1, THF)	-14.7 °
Ilahleko ekomisweni	<0.50%	0.25%
Ukuqukumbela	Le Mveliso ngokuHlolwa kweZivumelwano kunye noMgangatho woShishino
Usetyenziso oluphambili	abaPhakathi bamayeza;I-Glatiramer Acetate ePhakathi

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Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

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Isicelo:

I-5-Benzyl L-Glutamate N-Carboxyanhydride (H-Glu (OBzl)-NCA) (i-CAS: 3190-71-4) isetyenziswe njenge-pharmaceutical intermediates.I-H-Glu (OBzl)-NCA ingasetyenziselwa njenge-intermediate ye-Glatiramer Acetate (CAS: 147245-92-9).I-Glatiramer Acetate i-random basic synthetic copolymer ye-L-alanine, i-L-lysine, i-l-glutamic acid kunye ne-L-tyrosine kwi-molar ratio ye-6: 1.9: 4.7: 1.I-Glatiramer acetate yi-immunomodulator esetyenziselwa unyango lwe-multiple sclerosis.I-5-Benzyl L-Glutamate N-Carboxyanhydridei-derivative esebenzayo ye-L-glutamic acid, apho i-amino acid iye yajikeleza njenge-N-carboxyanhydride (NCA), iklasi ye-reagent eyaziwa ngokuba yi-Leuchs 'anhydrides.I-5-Benzyl L-Glutamate N-Carboxyanhydride iphendula kunye ne-nucleophiles efana ne-alcohol kunye ne-amines ukwenza i-esters kunye ne-amide ngokulandelanayo.Ukuvulwa kwe-N-carboxyanhydride kwi-ester okanye i-amide ikhupha i-amino acid amine enokuthi iphinde iphendule njenge-nucleophile ekhokelela kwi-polymerisation.Ezi polymers ze-poly-amide ziye zaphandwa njengamaqonga okuhanjiswa kwe-Small Interfering RNA (si-RNA).