Histrelin Acetate CAS 76712-82-8 Peptide Purity (HPLC) ≥98.0% Factory

Inkcazelo emfutshane:

Igama leMichiza: i-Histrelin Acetate

CAS: 76712-82-8

I-Peptide Purity (HPLC): ≥98.0%

Imbonakalo: I-White Lyophilized Powder

Iipeptide ze-GMP, uMgangatho oPhezulu, isikali soRhwebo

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili we-Histrelin Acetate (CAS: 76712-82-8) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lweepeptide ze-GMP.I-Ruifu inokubonelela ngenkonzo yehlabathi jikelele, ixabiso elikhuphisanayo, amanani amancinci kunye nesixa esikhulu esikhoyo.Thenga i-Histrelin Acetate,Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	Histrelin Acetate
Izithethantonye	Histrelin;i-Histrelin Acetic Acid iTyuwa;Igama lebrand Supprelin (Roberts Pharmaceutical);[des-Gly 10, D-His(Bzl) 6]-LH-RH Ethylamide;5-oxo-L-Prolyl-L-Histidyl-L-Tryptophyl-Lseryl- L-Tyrosyl-Nt-Benzyl-D-Histidyl-L-Leucyl-L-Arginyl-N-Ethyl-L-Prolinamide Diacetate
Ulandelelwano lwePeptide	Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-Arg-Pro-NHEt Acetate Salt
Uhlobo lweTyuwa	IAcetate
Ubume beStokhwe	Kwisitokhwe, isikali soRhwebo
Inombolo yeCAS	76712-82-8
Ifomula yeemolekyuli	I-C66H86N18O12
Ubunzima beMolekyuli	1323.52 g/mol
Ukuxinana	1.46±0.10 g/cm3
Inovakalelo	Hygroscopic.Ukungenwa kukufuma
Ugcino Temp.	Indawo epholileyo neyomileyo (2~8℃).Isikhenkcisi
I-COA kunye ne-MSDS	Iyafumaneka
Udidi	GMP Peptides
Beka ubomi kwishelufa	Iinyanga ezingama-24 ukusuka kumhla wokuveliswa ukuba zigcinwe ngokufanelekileyo
Uphawu	Ruifu Chemical

Iinkcukacha:

Izinto	ImiGangatho yokuHlola	Iziphumo
Imbonakalo	Umgubo oMhlophe weLyophilized	Iyahambelana
Ukunyibilika	I-Soluble emanzini okanye i-1% ye-Acetic Acid kwi-Concentration ye-≥1mg / ml ukunika isisombululo esicacileyo esingenambala.	Iyahambelana
MS	Ubunzima beMonoisotopic: 1323±1.0	1323.1
Identity HPLC	Kuyafana neSisombululo seReference	Iyahambelana
Uhlalutyo lwe-Amino Acid	Ser: ekhoyo	Iyahambelana
	Glu: 0.85 ~ 1.1	0.95
	Ipro: 0.85~1.1	1.05
	Leu: 0.85~1.1	1.01
	Tyr: 0.85~1.1	1.00
	Yakhe: 1.70 ~ 2.2	0.99
	Arg: 0.85~1.1	0.98
	Trp: ngoku	Uzimisele
I-Peptide Purity (HPLC)	≥98.0%	99.58%
Izinto eziyeleleneyo (HPLC)	Ukungcola ngokupheleleyo(%) ≤2.0%	0.42%
Izinto eziyeleleneyo (HPLC)	Nakuphi na okunye ukungcola ≤1.0%	0.24%
Umxholo weAcetate (HPLC)	≤12.0%	11.5%
Isiqulatho samanzi (uKarl Fischer)	≤5.0%	1.0%
Isivavanyi	95.0 ~ 105.0% (I-Anhydrous, i-Acetic Free)	98.5%
Imvelaphi yeMveliso	Ukwenziwa
Ingqalelo	Kuphela kuPhando, hayi usetyenziso lwabantu
Ukuqukumbela	Imveliso ivavanyiwe kwaye iyahambelana neenkcukacha

Ukupakishwa/uGcino/Ukuhambisa ngenqanawe:

Umqulu:Iplastiki yeplastiki (enikezelwe ukupakishwa kwepeptide) okanye iglasi yeglasi, ubungakanani ngokwemfuno yeenkcukacha zomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo neyomileyo (2~8℃) kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuhambisa ngenqanawe:Zisa kwihlabathi liphela ngeFedEx / DHL Express.Ukubonelela ngokukhawuleza nangokuthembekileyo.

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.

Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.

Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.

UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.

Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.

Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.

MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.

Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.

Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.

Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.

Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.

Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.

76712-82-8 - Umngcipheko kunye noKhuseleko:

Iimpawu zeHazard T - zinetyhefu
Iikhowudi zoMngcipheko
60 - Ingaphazamisa ukuchuma
Inkcazelo yoKhuseleko
S53-Kuphephe ukuvezwa-fumana imiyalelo ekhethekileyo phambi kokusetyenziswa.
S22 - Musa ukuphefumla uthuli.
S36/37/39 - Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
S45 - Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ileyibhile nanini na kunokwenzeka.)
WGK eJamani 3
RTECS OK6370800

Isicelo:

I-Histrelin Acetate (i-CAS: 76712-82-8), i-agonist yokwenziwa kwe-gonadotrophin-releasing hormone (GnRH), yaziswa njengonyango lokuqala lonyango lwe-central precocious puberty.Xa ilawulwa ixesha elide, icinezela ukukhululwa kwe-gonadotrophin, inqanda i-ovarian kunye ne-testicular steroidogenesis, kwaye ikhusela ukukhula ngokwesondo.Iphezulu kunyango lwesintu kunye nee-progestational agents, i-histrelin ibonakala ineempembelelo ezinciphisa ukuvuthwa kwamathambo okuvumela ukukhula okusemgangathweni kunye nokwandisa kakhulu ubude bokugqibela bomntu omdala.I-Histrelin ikwasetyenziselwe ukunyanga ezinye iziphazamiso ezibandakanya i-endometriosis, isifo se-polycystic ovarian, i-uterine leiomyomas, i-premenstrual syndrome eqatha kunye nokuthintela i-acute intermittent porphyria.
Inkcazo: I-oligopeptide equka i-pyroglutamyl, i-histidyl, i-tryptophyl, i-seryl, i-tyrosyl, i-1-benzyl-D-histidyl, i-leucyl, i-arginyl, kunye ne-N-ethylprolinamide iintsalela ezidibeneyo ngokulandelelana.Yi-analogue yokwenziwa ye-nonapeptide ye-gonadotro ekukhupheni ihomoni, kwaye isetyenziswa njengokufakelwa kwe-hydrogel engaphantsi kwesikhumba (ingakumbi njengetyuwa ye-diacetate) kunyango lomhlaza wedlala lobudoda kunye nokucinezela ukuveliswa kwehomoni yesini kubantwana abakwishumi elivisayo.Isetyenziselwa ukufikisa kwangaphambili.
Izenzo ze-Biochem / Physiol: I-Histrelin Acetate yi-GnRH (i-gonadotropin-releasing hormone) i-agonist, i-hiterelin.I-GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), ekwabizwa ngokuba yi-LHRH (i-luteinizing hormone-releasing hormone) okanye i-gonadorelin, ibalulekile ekuzaleni kwezilwanyana ezanyisayo kwaye ikhutshwe i-hypothalamic neurons.Ijongene nemfihlo ye-gonadotropins, i-hormone ye-luteinizing (LH) kunye ne-follicle-stimulating hormone (FSH), ukusuka kwiingqungquthela ze-pituitary.Utshintsho kwi-GnRH lunxulunyaniswa ne-normosmic congenital hypogonadotropic hypogonadism.I-Histerelin isetyenziselwa unyango lwe-central precocious puberty ebantwaneni.Ithintela izenzo ze-sex steroids kumalungu okuzala abesilisa nabasetyhini.
Ifumaneka njengenaliti yemihla ngemihla ye-intramuscular.I-Histrelin iyafumaneka kwakhona kwi-12-inyanga yokufakelwa kwe-subcutaneous (Vantas) yonyango lwe-palliative yomhlaza we-prostate ophezulu (ukususela ngo-2005 e-US, kwaye ukususela ngo-Jan 2010 e-UK. I-12-month subcutaneous implant (Supprelin LA) ye-central precocious ukufikisa (i-CPP) yamkelwa ngoMeyi 3, 2007 yi-US Food and Drug Administration.