Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Ubunyulu > 99.0% (HPLC)

Inkcazelo emfutshane:

Igama leKhemikhali: Ibrutinib Deacryloylpiperidine

CAS: 330786-24-8

Ubunyulu: >99.0% (HPLC)

Imbonakalo: I-Off-White ukuya kwi-Khaki Powder

Umbindi we-Ibrutinib (CAS: 936563-96-1)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ibrutinib eNxulumene nayo:
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
I-4-Phenoxyphenylboronic Acid CAS 51067-38-0
Ibrutinib Intermediate N-2 CAS 330786-24-8
Ibrutinib Intermediate N-3 CAS 330792-70-6
Ibrutinib CAS 936563-96-1

Iipropati zeMichiza:

Igama leMchiza	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Izithethantonye	Ibrutinib phakathi kwe-N-2;Ibrutinib Deacryloylpiperidine;Ukungcola kwe-Ibrutinib 8;I-5-(4-Phenoxyphenyl) -7H-pyrrolo[2,3-d] pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl Ukungcola
Inombolo yeCAS	330786-24-8
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C17H13N5O
Ubunzima beMolekyuli	303.32
Indawo yokunyibilika	>262℃(ngoDisemba)
Ukuxinana	1.380±0.06 g/cm3
IKlasi yeeNgozi	6.1;Ityhefu
Iqela lokuPakisha	III
I-COA kunye ne-MSDS	Iyafumaneka
Imvelaphi	Shanghai, China
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	I-Off-White ukuya kwi-Khaki Powder
Ukuchongwa	HNMR, LC-MS
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)
Ilahleko ekomisweni	<1.00%
UMax omnye.Ukungcola	<1.00%
Ukungcola ngokupheleleyo	<1.00%
Iintsimbi ezinzima (njenge Pb)	<20ppm
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi we-Ibrutinib (CAS: 936563-96-1)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

FAQ:

330786-24-8 - Isicelo:

I-3- (4-Phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-4-amine (CAS: 330786-24-8) i-synthetic intermediate esebenzayo kwi-synthesis ye-Ibrutinib (CAS: 936563-96-1) ).I-Ibrutinib luhlobo lwe-Bruton tyrosine kinase (BTK) inhibitor, ingasetyenziselwa unyango lwe-lymphocytic leukemia engapheliyo (CLL) kunye ne-mantle cell lymphoma (MCL).I-MCL kunye ne-CLL zeze-B-cell non-Hodgkin's lymphoma, ekunzima ukuyinyanga kwaye kulula ukuyiphinda.I-chemical immunotherapy eqhelekileyo ayinakho ukujoliswa, idla ngokuvela kwi-3 okanye i-4 yokusabela okubi.I-Ibrutinib kunye ne-B lymphocytes zinokujolisa nge-BTK eyimfuneko ekubunjweni, ukwahlula, kunye nokusasazwa kolwazi, inqanda umsebenzi we-BTK ngokungaguqukiyo, kwaye inqanda ukwanda kweeseli zesisu kunye nokuphila ngokufanelekileyo.I-Ibrutinib inokuthi ifakwe ngokukhawuleza emva kokulawulwa komlomo, ngexesha le-1 ~ 2h ifikelele ekugxininiseni kwegazi eliphezulu, ukusabela okungalunganga kukunye okanye ezimbini, ngoko ke, i-Ibrutinib iya kuba yinto entsha yonyango lwe-CLL kunye ne-MCL.