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N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity High Featured Image
  • N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Inkcazelo emfutshane:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

CAS: 152460-09-8

Imbonakalo: Umgubo oMthubi okanye ophantse watyheli

Ubunyulu: ≥98.0% (HPLC)

Phakathi kwe-Imatinib Mesylate (CAS: 220127-57-1) kunyango lwe-Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph + CML)

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo i-Imatinib Mesylate kunye nabaPhakathi abaNxulumeneyo:
I-Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8

Iipropati zeMichiza:

Igama leMchiza N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Izithethantonye I-Imatinib Mesylate ePhakathi;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
Inombolo yeCAS 152460-09-8
Inombolo yeCAT RF-PI228
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C16H13N5O2
Ubunzima beMolekyuli 307.31
Indawo yokunyibilika 188.0 ~ 193.0℃
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo oMthubi okanye ophantse watyheli
Ubunyulu ≥98.0% (HPLC)
Ukufuma (KF) ≤0.50%
Ukungcola ngokupheleleyo ≤2.0%
Ukungacoceki okuphezulu okukodwa ≤1.0%
Intsalela ekutshisweni ≤0.50%
Iintsimbi ezinzima ≤20ppm
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Phakathi kwe-Imatinib Mesylate (CAS: 220127-57-1)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-N- (2-Methyl-5-nitrophenyl) -4- (pyridin-3-yl) pyrimidin-2-amine (CAS: 152460-09-8) ngomgangatho ophezulu.Yinto ephakathi ngokuqhelekileyo kwi-synthesis ye-Imatinib Mesylate (CAS: 220127-57-1).
I-Imatinib Mesylate yi-molecule encinci evimbela i-c-Abl protein-tyrosine kinase, I-Highly specific for BCR-ABL, i-enzyme ehambelana ne-chronic myelogenous leukemia (CML) kunye neendlela ezithile ze-acute lymphoblastic leukemia (ALL).Isiganeko sokudluliselwa phakathi kwe-chromosomes 9 kunye ne-22 ivelisa i-chromosome yasePhiladelphia, ethi emva koko ivelise iprotheni ye-Bcr-Abl ye-fusion kunye nomsebenzi we-aberrant kinase okhuthaza ukwanda kweeseli ngokukhawuleza.I-Imatinib Mesylate ibophelela le kinase ibalulekileyo, imisa ukukhula okunxulumene ne-CML.I-Imatinib Mesylate iye yaboniswa ngakumbi ukuvimbela i-PDGFR kunye ne-tyrosine kinases ehambelana ne-c-Kit.Iifomyula eziqulethe i-Imatinib Mesylate zisetyenziswe kunyango lwee-cancer ezahlukeneyo.

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