Indapamide CAS 26807-65-8 Purity ≥99.5% (HPLC) API EP IFactory esemgangathweni oPhezulu
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi okhokelayo kunye nomthengisi we-Indapamide kunye nabaphakathi abanxulumene nomgangatho ophezulu.
Indapamide CAS 26807-65-8
I-2-Methylindoline CAS 6872-06-6
I-1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
| Igama leMchiza | Indapamide |
| Izithethantonye | N-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline |
| Inombolo yeCAS | 26807-65-8 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C16H16ClN3O3S |
| Ubunzima beMolekyuli | 365.83 |
| Indawo yokunyibilika | 160.0 ~ 162.0℃ |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe |
| Ukunyibilika | Ayinyibiliki ngokupheleleyo emanzini;Inyibilika kwi-Ethanol |
| Isazisi A | I-Ultraviolet kunye ne-Visible Absorption Spectrophotometry |
| Isazisi B | I-Infrared Absorption Spectrophotometry |
| Isazisi C | I-Chromatography ene-Thin-layer |
| Ukujikeleziswa kwe-Optical | -0.80°~ +0.80° (C=5, C2H5OH) |
| Amanzi (EP 2.5.12) | <3.00% |
| Uthuthu lweSulfate (EP 2.4.14) | <0.10% |
| Iintsimbi ezinzima (EP 2.4.8) | <10ppm |
| Izinto ezinxulumeneyo | |
| Ukungcola B | <0.30% |
| Ukungcola Okungachazwanga | <0.10% |
| Ukungcola ngokupheleleyo | <0.50% |
| Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) |
| Umgangatho woVavanyo | EP Umgangatho |
| Ukusetyenziswa | API;I-Antihypertensive kunye ne-Diuretic |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
Indapamide (CAS: 26807-65-8) i-antihypertensive kunye ne-diuretic.Ngokuthintela i-Na + reabsorption ekupheleni kwe-distal conflexion tubules, ivelisa umphumo we-diuretic kwaye iphinda ivimbele ukungena kwe-Ca2 +.Inokukhethwa okuphezulu kwi-vascular smooth muscle, iyancipha i-peripheral imikhumbi emincinci kwaye ivelise umphumo we-hypotensive.Kodwa impembelelo kwi-vascular smooth muscle eyomeleleyo isiphumo se-diuretic, ngaphantsi kweedosi ze-diuretic inokuhla, iidosi eziphezulu zibonise umphumo we-diuretic, kodwa akukho kusilela kwe-thiazide diuretic, okungabangeli i-orthostatic hypotension, i-flush kunye ne-reflect tachycardia, kumfanekiso wegazi, i-metabolism yegazi. amafutha, iswekile kunye nomsebenzi wezintso nawo awuzange ube nempembelelo ecacileyo, iidosi zonyango zokubetha kwentliziyo, ukuphuma kwentliziyo, akukho tshintsho lubalulekileyo kwi-electrocardiogram (ecg) yayingenayo impembelelo ecacileyo kwinkqubo ye-nervous central kunye ne-autonomic nerve.Ukulawulwa komlomo we-2 ~ 3 ye-chemicalbook H yavelisa umphumo we-hypotensive, owagcinwa kwi-24h.Isiphumo se-diuretic sibonakala kwi-3h kwaye sifikelele kwisiphumo sayo esiphezulu kwi-4 ~ 6h.I-Indapamide ifanelekile kwi-hypertension ephantsi kunye nephakathi, ingasetyenziselwa ukuhluleka kwentliziyo ebangelwa ukugcinwa kwe-sodium yamanzi, kunye nokusilela kwezintso kuyasebenza nakwizigulane ezinoxinzelelo lwegazi oluphezulu, isifo sikashukela, i-hyperlipidemia, ukusebenzisa i-antihypertensive effect iyamangalisa.
