Inosine CAS 58-63-9 Assay 98.0 ~ 102.0% Factory High Quality
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-Inosine (i-CAS: i-58-63-9) enomgangatho ophezulu, ihlangabezana nomgangatho we-Chinese Pharmacopoeia ChP2020 II.Iimveliso zethu zithengiswa ikakhulu eMelika naseYurophu, eIndiya, nakwiinkampani ezaziwayo zamayeza eTshayina.Iimveliso ziye zafumana udumo oluphezulu kwiimarike zamazwe ngamazwe kunye nezasekhaya.Sinokubonelela ngeenkonzo zehlabathi, ezincinci kunye nezixa ezininzi ezikhoyo.Ukuba unomdla kwi-Inosine (CAS: 58-63-9),Please contact: alvin@ruifuchem.com
Igama leMchiza | Inosine |
Izithethantonye | (-)-Inosine;I-Hypoxanthine 9-β-D-Ribofuranoside;I-Hypoxanthine-9-beta-D-Ribofuranoside;Atorel;i-beta-Inosine;I-Hypoxanthine D-Riboside;I-1,9-Dihydro-9-β-D-Ribofuranosyl-6H-purin-6-enye;I-Hypoxanthine Riboside;I-Hypoxanthine Ribonucleoside;I-9-β-D-Ribofuranosylhypoxanthine |
Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezingama-30 ngenyanga |
Inombolo yeCAS | 58-63-9 |
Ifomula yeemolekyuli | I-C10H12N4O5 |
Ubunzima beMolekyuli | 268.23 |
Indawo yokunyibilika | 222.0~226.0℃(dec.) (lit.) |
Inovakalelo | Hygroscopic |
Ukunyibilika | I-Soluble kancinane kuManzi, i-Insoluble kwi-Ethanol, kwaye i-Soluble kwi-Dilute Hydrochloric Acid kunye neSodium Hydroxide Solution. |
Ivumba | Ayinavumba |
Ugcino Temp. | Itywinwe kwindawo eyomileyo, iVenkile kwindawo yobushushu beGumbi |
I-COA kunye ne-MSDS | Iyafumaneka |
Uphawu | Ruifu Chemical |
Iikhowudi zeNgozi | Xi - Uyacaphukisa | RTECS | NM7460000 |
Iingxelo zoMngcipheko | 36/37/38 | F | 10 |
Iingxelo zoKhuseleko | 24/25-36-26 | I-TSCA | Ewe |
WGK eJamani | 2 | Ikhowudi ye-HS | 2934993090 |
Izinto | ImiGangatho yokuHlola | Iziphumo |
Imbonakalo | Iikristale eziMhlophe okanye iPowder yeCrystalline;Ayinavumba;Incasa Ekrakra kancinane | Iyahambelana |
Ukuchongwa | 1) Bonisa iRection eNgcono 2) Ixesha lokuGcina lihambelana noMgangatho wesi-3) ukufunxwa kwe-infraned | Iyahambelana |
Imeko yesisombululo (iTransmittance) | ≥98.0% | Iyahambelana |
Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
IArsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Ilahleko ekomisweni | ≤1.00% (kwi-105℃ kwiiyure ze-3) | 0.40% |
Intsalela ekutshisweni (iSulfated) | ≤0.20% | 0.07% |
Izinto ezinxulumeneyo | Umphezulu wokungcola uwonke ungaphezulu kwe-1.0% yendawo yokukroba ngokubanzi | Iyahambelana |
Isivavanyi | 98.0 ukuya kwi-102.0% | 99.4% |
Ixabiso le-pH | 4.8 ukuya ku-5.8 (1.0g kwi-100ml ye-H2O) | 5.0 |
Iimvavanyo zeMicrobiological | ||
Iyonke imida yeAerobic | ≤800CFU/g | 40CFU/g |
Iyonke imida yokuMngunda | ≤80 CFU/g | 10CFU/g |
Igwele | ≤80 CFU/g | 10CFU/g |
Escherichia Coli | Ibi | Ibi |
Ukuqukumbela | Idibana noMgangatho we-ChP2020 II |
Inosine (CAS: 58-63-9) Indlela yoVavanyo lweChP2020
Inosine - INKCAZELO
Umxholo we-C10H12N4O5 uya kuba phakathi kwe-98.0% kunye ne-102.0% ebalwa kwimveliso eyomileyo.
Inosine - Trait Le mveliso ngumgubo omhlophe wekristale;Ayinavumba.Le mveliso inyibilika kancinane emanzini, ayinyibiliki kwi-ethanol, kwaye i-soluble kwi-dilute hydrochloric acid kunye nesisombululo se-sodium hydroxide.
Inosine - IDENTIFICATION
1. Thatha umlinganiselo ochanekileyo wesisombululo se-0.01% sale mveliso, yongeza umthamo olinganayo we-3, isisombululo se-5-dihydroxytoluene (thatha i-3, i-5-dihydroxytoluene kunye ne-ferric chloride 0.lg, yongeza i-hydrochloric acid ukwenza i-100ml), xuba kakuhle, emva ukufudumeza kwindawo yokuhlambela amanzi malunga nemizuzu eyi-10, umbala oluhlaza wabonwa.
2. Kwichromatogram erekhodiweyo phantsi kwento yokumisela umxholo, ixesha lokugcinwa kweyona nto iphambili yesisombululo sovavanyo kufuneka lihambelane nexesha lokugcinwa kweyona nto iphambili yesisombululo sereferensi.
3. I-spectrum yokufunxa i-infrared yale mveliso kufuneka ihambelane naleyo yolawulo (i-Spectrum set 605).
Inosine - Uhlalutyo
Ukuhanjiswa kwesisombululo
Thatha i-0.5g yale mveliso, yongeza i-50ml yamanzi ukuchithwa, ngokwe-spectrophotometry ebonakalayo ye-UV (umgaqo jikelele we-0401), unqume ukuhanjiswa kwi-430nm wavelength, engekho ngaphantsi kwe-98.0%.(Yenaliti)
Izinto ezinxulumeneyo
Thatha le mveliso, yongeza amanzi ukuze uchithe kwaye uhlambulule ukwenza isisombululo esiqukethe i-0.5mg nge-1ml njengesisombululo sovavanyo;Thatha i-1ml yokulinganisa ngokuchanekileyo, uyibeke kwi-flask yokulinganisa i-100ml, yihlambulule ngamanzi kwisikali, njengesisombululo sokulawula.Ngokweemeko zechromatographic phantsi kwento yokumisela umxholo, i-20 u1 yesisombululo sovavanyo kunye nesisombululo sokulawula ngokulandelelana sijojowe kwi-chromatograph ye-liquid, kwaye i-chromatogram irekhodwa kumaxesha angama-2 okugcinwa kwexesha eliphambili.Ukuba kukho iincopho zokungcola kwichromatogram yesisombululo sovavanyo, isamba sendawo yokungcola nganye ayiyi kuba nkulu kunommandla oyintloko wesisombululo solawulo (1.0%).
Ilahleko ekomisweni
Thatha le mveliso, yomile ukuya kwisisindo esingaguqukiyo kwi-105 ° C, ukulahleka kwesisindo akuyi kudlula i-1.0% (Umgaqo jikelele we-0831).
Intsalela ekutshisweni (iSulfated)
Akukho ngaphezu kwe-0.1% (i-injection), okanye ingabi ngaphezu kwe-0.2% (ukusetyenziswa komlomo) (Umgaqo Jikelele we-0841).
Iintsimbi ezinzima
Thatha le mveliso 1.0g, ukuhlolwa ngokomthetho (General Principles 0821 umthetho wesibini), equlathe metals enzima akayi kudlula 10 iinxalenye ngesigidi.
Ubuthi obungaqhelekanga
Thatha le mveliso, yongeza inaliti ye-sodium chloride ukuze uchithe kwaye uhlambulule isisombululo esiqulethe i-inosine 10mg nge-1ml, khangela ngokomthetho (umgaqo jikelele we-1141), kufuneka uhambelane nemimiselo.(Yenaliti)
Inosine - Ukuzimisela komxholo
Ilinganiswe ngeKhromatografi yoLwalo oluSebenza ngokuPhezulu (Jikelele 0512).
Iimeko zeChromatographic kunye nokufaneleka kwenkqubo yokuvavanya ijeli ye-silica edityaniswe ne-alkyl silane elishumi elinesibhozo isetyenziswe njengesizaliso;IMethanol-water (10:90) yayisetyenziswa njengenqanaba elihambayo;Ubude bokubona ubude be-248nm.Thatha malunga ne-10mg yereferensi ye-inosine, yongeza i-1 mol / L isisombululo se-hydrochloric acid (1ml), ukushisa kwindawo yokuhlamba amanzi kwi-80 ℃ imizuzu eyi-10, yiyeke ipholile, yongeza i-1ml ye-1 mol / L isisombululo se-sodium hydroxide, yongeza amanzi kwi-50ml, I-20u1 ye-chromatograph yolwelo lwesitofu, ukulungelelanisa inkqubo yechromatographic, idigri yokwahlukana kwencopho ye-inosine kunye nencopho yokungcola ekufutshane kufuneka ihlangabezane neemfuno, inani lepleyiti yethiyori ngokwezibalo ze-inosine peak ayikho ngaphantsi kwe-2000.
Isivavanyi
Thatha isixa esifanelekileyo sale mveliso, uyilinganise ngokuchanekileyo, yongeza amanzi ukuze unyibilike kwaye uhlambulule ngokobungakanani ukwenza isisombululo esiqulethe malunga ne-20ug nge-lml nganye, uyishukumise, kwaye uyisebenzise njengesisombululo sovavanyo, I-20ul injection liquid chromatograph yalinganiswa ngokuchanekileyo kwaye ichromatogram yarekhodwa.Isixa esifanelekileyo sereferensi ye-inosine silinganiswe ngokuchanekileyo kwaye sinqunywe ngendlela efanayo, kwaye indawo ephakamileyo ibalwa ngokwendlela yomgangatho wangaphandle.
Inosine - Udidi
I-cell metabolism iphucula iziyobisi.
Inosine - Ukugcinwa
Ukukhusela ukukhanya, ukugcinwa okuvaliweyo.
Pharmaceuticals: (1) Inosine Oral Solution (2) Inosine Tablets (3) Inosine Injection (4) Inosine Capsules (5) Inosine kunye neGlucose Injection (6) Inosine kunye neSodium Chloride Injection (7) Inosine for Injection
Iphakheji: Ibhotile eFluorinated, 25kg/bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
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UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
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Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
1. I-Inosine (i-CAS: i-58-63-9), njengemveliso ye-nucleoside, isetyenziselwa ukuvelisa iziyobisi zokunyanga izifo zentsholongwane kunye nezinye izifo.
2. Inosine yi-nucleotide engekho-canonical ekhoyo kakhulu njenge-monophosphate.Inamandla okuseka isibini kunye ne-deoxythymidine, i-deoxyadenosine kunye ne-deoxyguanosine.Ukufakwa kwe-inosine endaweni ye-guanine kulungelelanisa imicimbi yoguqulelo.I-Inosine ine-antioxidant, i-anti-inflammatory kunye nokusebenza kwe-neuroprotective.I-Inosine imiselwe njengesongezelelo sonyango lokulimala kwe-nerve, ukuvuvukala kunye noxinzelelo lwe-oxidative.Ilungisa iinkqubo zebhayoloji ngokusebenzisa i-adenosine receptors.Yandisa ukuphuma kwe-neurite kwingxaki yokudakumba nge-adenosine receptors.Inosine ikwasetyenziselwa ukunyanga i-sepsis kwizifo.
3. I-Inosine yinto ebalulekileyo yomzimba womntu, uhlobo lwechiza le-coenzyme elisetyenziswa kakhulu kumayeza nakwishishini lokutya.Iyakwazi ukungena kwi-membrane yeseli kwiseli yomzimba ngokuthe ngqo, kwaye yenze iseli ikwimo yokungabi nangqondo kwaye i-anoxia iqhubeke nokumetabolise kakuhle.Kwaye inokwenza i-caetone acid oxides isebenze, kwaye ithathe inxaxheba kwiprotheni yomzimba ekuhlanganiseni.
Ukusetyenziswa kwamachiza e-Inosine, njenge-Inosine Tablets kunye ne-Inosine Injection
1. Isetyenziswe kunyango lwe-leukopenia kunye ne-thrombocytopenia.
2. Kunyango lwe-hepatitis enzima kunye ne-hepatitis engapheliyo kunye ne-cirrhosis yesibindi, i-hepatic encephalopathy.
3. Isetyenziselwa i-coronary atherosclerotic heart disease (i-coronary heart disease), i-myocardial infarction, isifo senhliziyo ye-rheumatic, i-cor pulmonale encedisayo yokusetyenziswa kweziyobisi.
4. Isetyenziselwa ukuthintela kunye nokunciphisa amachiza othintelo lweschistosomiasis abangelwa yintliziyo kunye netyhefu yesibindi.
5. Isetyenziselwa izifo zamehlo (ukuvutha kwe-retinal ephakathi, i-optic atrophy) ukusetyenziswa kweziyobisi ezincedisayo.
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