Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Purity >99.0% (HPLC) Factory

Inkcazelo emfutshane:

Igama leKhemikhali: 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride

Izithethantonye: Irbesartan Side Chain Hydrochloride

CAS: 151257-01-1

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Mhlophe ukuya Phantse eMhlophe Umgubo weCrystalline

Umbindi we-Irbesartan (CAS: 138402-11-6)

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

IRuifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
I-TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1

Iipropati zeMichiza:

Igama leMchiza	2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride
Izithethantonye	I-Irbesartan Side Chain Hydrochloride;Ukungacoceki kwe-Irbesartan Lactam;Ukungacoceki kwe-Irbesartan A;I-2-Butyl-4-spirocyclopentane-2-imidazolin-5-enye iHydrochloride;2-Butyl-1,3-diaza-spiro[4.4]non-1-en-4-enye iHCl
Inombolo yeCAS	151257-01-1
Inombolo yeCAT	RF-PI1894
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C11H18N2O·HCl
Ubunzima beMolekyuli	230.74
Ukunyibilika emanzini	Inyibilika emanzini
Indawo yokunyibilika	235.0 ~ 240.0℃
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya Phantse uMhlophe Umgubo weCrystalline
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)
Ilahleko ekomisweni	<0.50%
Intsalela kwi-Ignition	<0.20%
Ukungcola ngokupheleleyo	<1.00%
Proton NMR Spectrum	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi we-Irbesartan (CAS: 138402-11-6)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-2-Butyl-1,3-diazaspiro [4.4] non-1-en-4-one Hydrochloride (CAS: 151257-01-1), eyaziwa ngokuba yi-Irbesartan Side Chain Hydrochloride, i-Irbesartan (Avapro) (i-CAS) : 138402-11-6).I-Irbesartan yi-angiotensin II receptor inhibitor, i-angiotensin II i-receptors yahlulwe kwi-AT1, AT2, i-irbesartan inokuthintela i-AngⅠtransform ibe yi-AngII ngokuvala ngokukhethayo i-AT1 receptor ye-AngII, ngokukodwa i-antagonize i-angiotensin eguqula i-enzyme ye-1 receptor (AT500), i-antagonism ye-AT500 amaxesha kune-AT2, inokuthintela i-vasoconstriction kunye nokukhululwa kwe-aldosterone ngokuthintela ngokukhethiweyo i-AngII ebophelelayo kunye ne-AT1 receptor kwaye ibangele umphumo we-antihypertensive.Le mveliso ayithinteli i-angiotensin yokuguqula i-enzyme (ACE), i-renin, kunye nezinye ii-receptors zehomoni, kwaye ayicinezeli ukulawulwa kwengcinezelo yegazi kunye nokulungelelaniswa kweziteshi ze-sodium ion.I-Irbesartan inokunciphisa ukulungiswa kombane kwi-myocardium, ngaloo ndlela inciphisa izinga lokufa kwezigulana ezinoxinzelelo lwegazi, lelona chiza lisebenzayo kunyango loxinzelelo lwegazi kunye nesifo sentliziyo.