Irinotecan Free Base CAS 97682-44-5 Assay ≥99.0% (HPLC) API Factory High Purity
Ubonelelo lwabavelisi be-Irinotecan kunye nabaPhakathi abaNxulumeneyo:
Irinotecan Hydrochloride CAS: 100286-90-6
I-Irinotecan Isiseko sasimahla seCAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
I-7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
I-1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Igama leMchiza | I-Irinotecan Free Base |
| Inombolo yeCAS | 97682-44-5 |
| Inombolo yeCAT | RF-API51 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | C33H38N4O6 |
| Ubunzima beMolekyuli | 586.68 |
| Indawo yokunyibilika | 222.0-223.0℃ |
| Imeko yokuthumela ngenqanawa | Phantsi koBubushushu be-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Umgubo oMthubi oKhanya |
| Ukuchongwa kwe-HPLC | Ixesha lokugcinwa kwesampulu lihambelana nelo RS |
| Ilahleko ekomisweni | ≤5.0% |
| UMax omnye.Ukungcola | ≤0.25% |
| Ukungcola ngokupheleleyo | ≤1.0% |
| Isivavanyi | ≥99.0% (HPLC) |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | API |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-Irinotecan Isiseko sasimahla yi-analog ye-camptothecin kunye ne-topoisomerase I inhibitor.Inokuthintela i-AChE.Isiseko sasimahla se-Irinotecan sisetyenziselwa ukunyanga umhlaza wekolon, kodwa ikwamodareyitha uthintelo lokwahlulahlula kweeseli ze-dendritic kunye nokunciphisa inani leenqanawa zamathumba kwiimodeli ze-glioma.I-Irinotecan ikhusela ukunyanzeliswa kwe-DNA strand ngokuzibophelela kwi-topoisomerase I-DNA complex.Ukwenziwa kolu luhlu lwe-ternary kuphazamisa ifolokhwe yokuphindaphinda ehambayo, eyenza ukuphindaphinda ukubanjwa kunye nekhefu elibulalayo eliphindwe kabini kwi-DNA.
