Ivabradine Hydrochloride CAS 148849-67-6 Ubunyulu > 99.5% (HPLC) API Factory
I-Ruifu Chemical Supply Ivabradine Hydrochloride Intermediate With High Purity
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Igama leMchiza | Ivabradine Hydrochloride |
Izithethantonye | Ivabradine HCl |
Inombolo yeCAS | 148849-67-6 |
Inombolo yeCAT | RF-PI1812 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C27H36N2O5·HCl |
Ubunzima beMolekyuli | 505.05 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ukuchongwa | I-HPLC/UV iyahambelana |
Ubunyulu / Indlela yokuHlalutya | >99.5% |
Ilahleko ekomisweni | <1.00% (Yomise kwi-105℃ kwi-dryer yombane evuthela umoya kude kube nobunzima obuqhubekayo) |
Umxholo wokufuma | <1.00% |
Intsalela kwi-Ignition | <0.20% |
Ukungahlambuluki Okukodwa okuphezulu | <0.50% |
Ukungcola ngokupheleleyo | <0.50% |
Isomer ye-Optical | <0.50% |
Isivavanyi | >99.5% |
Iintsimbi ezinzima | <20ppm |
Ukujikeleziswa okuthe ngqo | +6.5 ° ~ +8.5 ° (kwisiseko esomileyo, isisombululo se-1% kwi-DMSO) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
Ivabradine Hydrochloride (CAS: 148849-67-6),Ngomzamo wokuphuhlisa i-angina agents ngaphandle kwe-inotropic engafunwayo kunye nemiphumo ye-hypotensive ehambelana ne-b-adrenergic blockers kunye ne-calcium channel blockers, iklasi entsha yokunciphisa i-heart-reduction compounds esebenza ngokuthe ngqo kwi-node ye-sinoatrial (SA) ihlolwe.Ezi arhente ze-bradycardic zisebenzisana ngqo ne-pacemaking cell ye-SA node kunye ne-hyperpolarization- activated Ukuba i-primary pacemaking current.I-Ivabradine iye yavela njenge-inhibitor ethile ye-Ukuba yangoku ngokuqhagamshelana ne-f-channels kwicala le-intracellular ye-plasma membrane.Ngenxa yoko, i-Ivabradine inciphisa isantya se-diastolic depolarization kwaye iyancipha izinga lentliziyo.Kuvunyiwe unyango lwe-angina engapheliyo kwaye inika enye indlela esebenzayo kwizigulane ezine-contraindication okanye ukunyamezela kwe-b-blockers.Uvavanyo lukwaqhuba unyango olunokubakho lwe-ischemic heart disease.