I-L-Alaninamide Hydrochloride CAS 33208-99-0 (H-Ala-NH2 · HCl) i-Assay 98.0 ~ 102.0% i-Safinamide Intermediate Factory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-L-Alaninamide Hydrochloride (H-Ala-NH2 · HCl) (CAS: 33208-99-0) kunye nomgangatho ophezulu, ophakathi kwe-Safinamide (CAS: 133865- 89-1).Sinokubonelela ngeenkonzo zehlabathi, ezincinci kunye nezixa ezininzi ezikhoyo.Ukuba ufuna i-L-Alaninamide Hydrochloride,Please contact: alvin@ruifuchem.com
| Igama leMchiza | L-Alaninamide Hydrochloride |
| Izithethantonye | I-L-Alaninamide HCl;H-Ala-NH2·HCl;L-Ala-NH2·HCl;(S) -2-Aminopropionamide Hydrochloride;(S)-2-Aminopropionamide HCl;(2S) -2-Aminopropanamide Hydrochloride |
| Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezili-100 ngonyaka |
| Inombolo yeCAS | 33208-99-0 |
| Ifomula yeemolekyuli | C3H8N2O·HCl |
| Ubunzima beMolekyuli | 124.57 g/mol |
| Indawo yokunyibilika | 200.0 ~ 220.0℃ |
| Inovakalelo | Ubuthathaka bomoya |
| Ukunyibilika | Inyibilika kwiMethanol |
| Ugcino Temp. | Itywinwe kwindawo eyomileyo, iVenkile kwindawo yobushushu beGumbi |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Ukuhlelwa | Amino Acids & Derivatives |
| Uphawu | Ruifu Chemical |
| Iikhowudi zeNgozi | C - Iyadleka | WGK eJamani | 3 |
| Iingxelo zoKhuseleko | 24/25 - Gwema ukudibana nolusu kunye namehlo. | Ikhowudi ye-HS | 2922491990 |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Mhlophe ukuya kwi-Off-White Powder | Iyahambelana |
| I-Infrared Spectrometry | Iyahambelana neSakhiwo | Iyahambelana |
| Indlela yoVavanyo / yoHlahlelo | 98.0~102.0% | 99.3% |
| Indawo yokunyibilika | 200.0 ~ 220.0℃ | 214.0 ~ 216.0℃ |
| Ukujikeleziswa okuthe ngqo [α]20/D | +9.0° ukuya +13.0°(C=1, CH3OH) | +12,43 ° |
| Ilahleko ekomisweni | <0.50% | 0.15% |
| Intsalela kwi-Ignition | <0.10% | 0.05% |
| Intsimbi (Fe) | <10ppm | <10ppm |
| Isulfate (SO4) | <0.02% | <0.02% |
| Iintsimbi ezinzima (Pb) | <10ppm | <10ppm |
| I-Ammonium (NH4) | <0.08% | <0.08% |
| IArsenic (As2O3) | <1ppm | <1ppm |
| Ukuqukumbela | Le Mveliso ngokuHlolwa kweZivumelwano kunye noMgangatho woShishino | |
| Usetyenziso oluphambili | abaPhakathi bamayeza;I-Safinamide ePhakathi | |
Iphakheji: Ibhotile eFluorinated, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
I-L-Alaninamide Hydrochloride (H-Ala-NH2 · HCl) (CAS: 33208-99-0) isetyenziswe njenge-pharmaceutical intermediates.I-L-Alaninamide Hydrochloride isetyenziselwa ukulungiselela izinto ezintsha ze-amide ze-steroidal[3,2-c]ikhompawundi zepyrazole ezinomsebenzi weglucocorticoid.I-L-Alaninamide Hydrochloride iphakathi kwe-Safinamide (CAS: 133865-89-1) kunye ne-Safinamide Mesylate (CAS: 202825-46-5).I-Safinamide yi-inhibitor ekhethiweyo kunye ne-reversible inhibitor ye-monoamine oxidase B (MAO-B, IC50 = 98 nM ene-selectivity engaphezu kwe-100 ngaphezulu kwe-MAO-A. Ibonisa umsebenzi we-anticonvulsant kwaye ikhusela ekubanjweni kwe-kainate-induced kunye ne-hippocampal neurodegeneration kwiimodeli zegundane. Ukubonisa ngokugqithisileyo kwe-glutamatergic ngokusebenzisa i-blockade yesiteshi sesodium exhomekeke kusetyenziso-Inoveli yonyango yesifo sika-Parkinson eneendlela ezininzi zesenzo.Isebenza njengokongeza kunyango lwe-dopamine agonist ekuqaleni kwe-Parkinson's. I-Safinamide methanesulfonate yamkelwa ngoFebruwari ka-2015 yi-EMA yonyango. Isifo sikaParkinson esiguquguqukayo esiphakathi ukuya ekupheleni.Olu kwamkelwa luquka ukusetyenziswa kwechiza njengonyango olongezelelekileyo ukuze lusetyenziswe neLevodopa, nokuba yodwa okanye idityaniswe nolunye unyango olukhoyo lwesifo sikaParkinson.Safinamide methanesulfonate, i-α-aminoamide yomlomo Ekuqaleni yafunyanwa yiFarmitalia Carlo Erba kwaye kamva yaphuhliswa nguNewron/Zambon, isebenza njenge-inhibitor ekhethiweyo kunye nebuyiselwa umva ye-MAO-B, ekhokelela kumanqanaba okwanda kwe-dopamine kunye nophuculo olulandelayo kwiimpawu zemoto zesifo sikaParkinson, iziphumo ebezingalindelekanga ezihlala zivela ukusetyenziswa kolunye unyango lwesintu oluxhomekeke kunyango lokubuyisela i-dopamine.
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