L-Serine CAS 56-45-1 (H-Ser-OH) Uvavanyo 98.5 ~ 101.0% Umgangatho ophezulu weFactory
I-Shanghai Ruifu Chemical Co., Ltd. ngumthengisi ohamba phambili we-L-Serine (H-Ser-OH; iSer efinyeziweyo okanye i-S) (i-CAS: 56-45-1) enomgangatho ophezulu.Njengomnye wababoneleli abakhulu be-amino acids e-China, i-Ruifu Chemical ibonelela nge-amino acids ihlangabezana ne-AJI, i-USP, i-EP, i-JP kunye nemigangatho ye-FCC.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kwi-L-Serine,Please contact: alvin@ruifuchem.com
| Igama leMchiza | L-Serine |
| Izithethantonye | H-Ser-OH;L-Ser;I-Ser efinyeziweyo okanye i-S;(-)-Serine;I-Serine;iLaevo-Serine;(S)-Serine;I-L-2-Amino-3-Hydroxypropionic Acid;(S) -2-Amino-3-Hydroxypropionic Acid;(S) -α-Amino-β-Hydroxypropionic Acid;I-L-3-Hydroxy-2-Aminopropionic Acid;I-3-Hydroxy-L-Alanine;β-Hydroxy-L-Alanine |
| Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezingama-500 ngonyaka |
| Inombolo yeCAS | 56-45-1 |
| Ifomula yeemolekyuli | C3H7NO3 |
| Ubunzima beMolekyuli | 105.09 |
| Indawo yokunyibilika | 222℃(dec.) (lit.) |
| Ukuxinana | 1.6 |
| Ukunyibilika kwamanzi | Inyibilika Emanzini, Phantse Ukungafihli |
| Ukunyibilika | Inyibilika ngokukhululekileyo kwiFormic Acid.Ayinyibiliki kwi-Ethanol nakwi-Ether.Inyibilika kwi-Dilute Hydrochloric Acid |
| Ugcino Temp. | Itywinwe kwindawo eyomileyo, iVenkile kwindawo yobushushu beGumbi |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Ukuhlelwa | Amino Acids & Derivatives |
| Uphawu | Ruifu Chemical |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Iikristale eziMhlophe okanye umgubo weCrystalline | Iyahambelana |
| Ukuchongwa | I-Infrared Absorption Spectrum | Iyahambelana |
| Ukujikeleziswa okuthe ngqo [α]20/D | +14.4° ukuya +15.5° (C=10, 2N HCl) | -33.8 ° |
| Imeko yesisombululo (iTransmittance) | Icacile kwaye ayinaMbala ≥98.0% | 98.6% |
| Ikloridi (Cl) | ≤0.020% | <0.020% |
| Isulfate (SO4) | ≤0.020% | <0.020% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Intsimbi (Fe) | ≤10ppm | <10ppm |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
| IArsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Ezinye iiAmino Acids | IChromatographically ayifumaneki | Iyahambelana |
| Ilahleko ekomisweni | ≤0.20% (kwi-105℃, iiyure ze-3) | 0.15% |
| Intsalela ekutshisweni (iSulfated) | ≤0.10% | 0.06% |
| Isivavanyi | 98.5 ukuya kwi-101.0% (Titration: Isiseko esomileyo) | 99.7% |
| Uvavanyo lwe-pH | 5.2 ukuya ku-6.2 (1.0g kwi-10ml ye-H2O) | 5.5 |
| Ukungcola okuguquguqukayo kwe-Organic | Iyahlangabezana neeMfuno | Iyahambelana |
| Imvelaphi | Umthombo ongengowalwanyana | Iyahambelana |
| Izinyibilikisi ezishiyekileyo | Iyahambelana | Iyahambelana |
| Ukuqukumbela | Idibana ne-AJI97, EP, USP, iJP Testing Specifications | |
| Beka ubomi kwishelufa | Iinyanga ezingama-24 ukusuka kumhla wokuveliswa ukuba zigcinwe ngokufanelekileyo | |
| Usetyenziso oluphambili | Izongezo zokutya;Amachiza;iSongezo seSondlo;njl. | |
Iphakheji: Ibhotile eFluorinated, 25kg/bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
JP16
I-L-Serine, xa yomisiwe, iqulethe ngaphantsi kwe-98.5% kwaye ingabi ngaphezu kwe-101.0% ye-C3H7NO3.
Inkcazo L-Serine yenzeka njengeekristale ezimhlophe okanye i-crystalline powder.Inencasa encinci eswiti.Inyibilika ngokukhululekileyo emanzini nakwi-asidi ye-formic, kwaye ayinyibiliki kwi-ethanol (99.5).Inyibilika kwi-2 mol / L i-hydrochloric acid TS.
Ukuchonga Ukuchonga i-spectrum ye-infrared yokufunxa ye-L-Serine njengoko iqondiswe kwindlela ye-potassium bromide disk phantsi kwe-Infrared Spectrophotometry<2.25>, kwaye uthelekise i-spectrum kunye ne-Reference Spectrum: zombini i-spectra ibonisa ubunzima obufanayo bokuxhamla kwiinombolo zamaza afanayo.
Ukujikeleza kwe-Optical <2.49> [a] 20D: + 14.0 ° ~ + 16.0 ° (Emva kokumisa, 2.5 g, 2 mol / L i-hydrochloric acid TS, 25 mL, 100 mm).
pH <2.54> I-pH yesisombululo esilungiselelwe ngokuchithwa kwe-1.0 g ye-L-Serine kwi-10 mL yamanzi iphakathi kwe-5.2 kunye ne-6.2.
Ubunyulu (1) Ukucaca kunye nombala wesisombululo-Dibanisa i-1.0 g ye-L-Serine kwi-10 mL yamanzi: isisombululo sicacile kwaye singenambala.
(2) I-Chloride <1.03>-Yenza uvavanyo nge-0.5 g ye-L-Serine.Lungisa isisombululo sokulawula nge-0.30 mL ye-0.01mol / L i-hydrochloric acid VS (kungekho ngaphezu kwe-0.021%)
(3) Sulfate <1.14> Yenza uvavanyo kunye ne-0.6 g ye-L-Serine.Lungiselela isisombululo sokulawula kunye ne-0.35 mL ye-0.005mol / L i-sulfuric acid VS (kungekho ngaphezu kwe-0.028%).
(4) Ammonium <1.02>-Yenza uvavanyo nge-0.25 g ye-L-Serine.Lungiselela isisombululo sokulawula kunye ne-5.0 mL ye-Standard Ammonium Solution (engekho ngaphezu kwe-0.02%).
(5) Iintsimbi ezinzima <1.07> Qhubeka ne-2.0 g ye-L-Serine ngokweNdlela ye-1, kwaye wenze uvavanyo.Lungiselela isisombululo solawulo kunye ne-2.0 mL yeSisombululo esiPhambili seNkokheli (kungekho ngaphezu kwe-10 ppm).
(6) Intsimbi <1.10> Lungiselela isisombululo sovavanyo kunye ne-1.0 g ye-L-Serine ngokweNdlela ye-1, kwaye wenze uvavanyo ngokweNdlela A. Lungisa isisombululo sokulawula kunye ne-1.0mL ye-Standard Iron Solution (kungekho ngaphezu kwe-10 ppm) .
(7) Izinto eziNxulumeneyo-Dissolve 0.10 g ye-L-Serine kwi-10mL yamanzi, kwaye usebenzise esi sisombululo njengesisombululo sesampuli.Umbhobho we-1 mL wesisombululo sesampulu, yongeza amanzi ukwenza i-10 mL ngqo.Ipayipi ye-1 mL yesi sisombululo, yongeza amanzi ukwenza ngokuchanekileyo i-50 mL, kwaye usebenzise esi sisombululo njengesisombululo esiqhelekileyo.Yenza uvavanyo ngezi zisombululo njengoko uqondiswe phantsi kwe-Thin-layer Chromatography<2.03>.Spot 5mLeachofthesamplesolution kunye nesisombululo esisemgangathweni kwipleyiti yejeli yesilica forthin-layer chromatography.Emva koko uphuhlise ngomxube we-1-butanol, amanzi kunye ne-acetic acid (100) (3: 1: 1) ukuya kumgama omalunga ne-10 cm, kwaye womise ipleyiti kwi-809C imizuzu engama-30.Isisombululo se-sprayevenly se-ninhydrinin umxube we-methanol andacetic acid (100) (97: 3) (1 kwi-100) kwi-plate, kunye nokufudumala kwe-80 ℃ imizuzu eyi-10: indawo ngaphandle kwendawo eyintloko efunyenwe kwisisombululo sesampuli ayikho. bukhali ngakumbi kunendawo ukusuka kwisisombululo esisezantsi.
Ilahleko ekomisweni <2.41> Akukho ngaphezu kwe-0.3% (1 g, 105℃, iiyure ezi-3).
Intsalela kwi-Ignition <2.44> Akukho ngaphezu kwe-0.1% (1 g).
I-Assay Ukulinganisa ngokuchanekileyo malunga ne-0.11 g ye-L-Serine, eyomisiwe ngaphambili, ichithe kwi-3 mL ye-formic acid, yongeza i-50 mL ye-acetic acid (100), kunye ne-titrate <2.50> kunye ne-0.1 mol / L perchloric acid VS (i-potentiometric titration).Yenza ukuzimisela okungenanto ngendlela efanayo, kwaye wenze naluphi na ulungiso oluyimfuneko.
I-mL nganye ye-0.1 mol/L ye-perchloric acid VS＝10.51 mg ye-C3H7NO3
Imigqomo kunye nokugcinwa Izikhongozeli-Tight izikhongozeli.
USP39-NF34
INGCACISO L-Serine iqulethe i-NLT 98.5% kunye ne-NMT 101.5% ye-L-serine (C3H7NO3), ibalwe ngokomisiweyo.
UKUCHAZA
A. UKUFUTSHWA KWE-IFRARED <197K>
UVAVANYO
INKQUBO
Isampuli: 100mg yeSerine
Akunanto: Xuba i-3mL ye-asidi ye-formic kunye ne-50mL ye-glacial acetic acid.
Inkqubo yeTitrimetric
(Jonga i-Titrimetry <541>)
Imowudi: Ukubhalwa ngokuthe ngqo
I-Titrant: 0.1 N i-perchloric acid VS
Ukubonwa kwendawo yokugqibela: I-Potentiometric
Uhlalutyo: Chitha iSampulu kwi-3mL ye-asidi ye-formic kunye ne-50mL ye-glacial acetic acid.Titrate kunye neTitrant.
Yenza ukuzimisela kweGank.
Bala ipesenti ye-serine (C3H7NO3) kwisampulu ethathiweyo:
Isiphumo = {[(VS-VB) xNxF]/W} x100
VS= Umthamo we-Titrant osetyenziswe yiSampuli (mL)
VB= Umthamo we-Titrant osetyenziswe yi-Gank (mL)
N= eyona nto iqhelekileyo ye-Titrant (mEq/mL)
F= i-equivalency factor, 105.1mg/mEq
W= Ubunzima besampulu (mg)
Iinqobo zokwamkela: 98.5% ~ 101.5% kwisiseko esomileyo
UBUNGCOLA
OKUSHIYELWE OKUSHIYELWE <281>: NMT 0.1%
I-CHLORIDEAND SULFATE, iChloride <221>
Isisombululo esisemgangathweni: 0.50mL ye-0.020 N i-hydrochloric acid
Isampulu: 0.73g yeSerine
Indlela yokwamkelwa: NMT 0.05%
I-CHLORIDEAND SULFATE, i-Sulfate <221>
Isisombululo esisemgangathweni: 0.10mL ye-0.020 N sulfuric acid
Isampulu: 0.33g yeSerine
Indlela yokwamkelwa: NMT 0.03%
I-IRON <241>: NMT 30ppm
Cima oku kulandelayo:
IIMETALI EZISINZI, Indlela I <231>: NMT 15ppm (Esemthethweni 1-Jan-201)
EZINXULUMENEYO
Isisombululo sokufaneleka kwenkqubo: 0.4mg / mL nganye ye-USP L-Serine RS kunye ne-USP L-Methionine RS kwi-0.1 N hydrochloric acid
Isisombululo esisemgangathweni: 0.05mg / mL ye-USP L-Serine RS kwi-0.1 N hydrochloric acid.[QAPHELA-Esi sisombululo sinogxininiso olulingana ne-0.5% yeso sisombululo seSampule.]
Isisombululo sesampuli: 10mg / mL yeSerine kwi-0.1 N hydrochloric acid
Inkqubo yeChromatographic Jonga i-Chromatography <621>, i-Thin-Layer Chromatography.)
Indlela: TLC
I-Adsorbent: 0.25-mm umaleko we-chromatographic umxube we-silica gel
Umthamo wesicelo: 5μL
Ukuphuhlisa inkqubo yokunyibilikisa: I-butyl alcohol, i-glacial acebutyl alcohol kunye ne-2N acetic acid (95:5)
Ukufaneleka kwenkqubo
Iimfuno zokufaneleka: Ichromatogram yesisombululo sokufaneleka kweSistim ibonisa amabala amabini ahluke ngokucacileyo.
Uhlalutyo
Iisampulu: isisombululo sokufaneleka kweNkqubo, isisombululo esiPhakathi, kunye nesisombululo seSampuli.
Emva kokumisa ipleyiti emoyeni, fafaza nge-Spray reagent, kwaye ushushu phakathi kwe-100 ° kunye ne-105 ° i-15 min.Hlola ipleyiti phantsi kokukhanya okumhlophe.
Iikhrayitheriya zokumkela: Nayiphi na indawo yesibini yesisombululo seSampuli ayinkulu okanye inamandla ngaphezu kwendawo eyintloko yesisombululo soMgangatho.
Ukungcola komntu ngamnye: NMT 0.5%
Ubumdaka bubonke: NMT 2.0%
IIMVAVANYO EZITHILE
UKUJONGANA KOMBONISO, Ukujikeleza okuthe ngqo <781S>
Isisombululo sesampuli: 100mg / mL kwi-2N i-hydrochloric acid
Iinqobo zokwamkela: +14.0 ° ukuya +15.6 °
I-LASSON YOKOMA <731>: Yomisa isampulu kwi-105℃ kangange-3 h: ilahlekelwa yi-NMT nge-0.2% yobunzima bayo.
IIMFUNO EZONGEZELELWEYO
UKUGCINWA KWE-ACKAGINGAND: Londoloza kwizikhongozeli ezivalwe kakuhle.
IMIGANGATHO YE-USP REFERENCE <11>
USP L-Methionine RS
USP L-Serine RS
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Amava Eminyaka Eli-15?Sineminyaka engaphezu kwe-15 yamava ekwenziweni nasekuthumeleni kumazwe angaphandle uluhlu olubanzi oluphezulu lwamayeza aphakathi okanye amachiza alungileyo.
Iimarike eziphambili?Thengisa kwimarike yasekhaya, eMntla Melika, eYurophu, eIndiya, eKorea, eJapan, eOstreliya, njl.
Iingenelo?Umgangatho ophezulu, ixabiso elifikelelekayo, iinkonzo zengcali kunye nenkxaso yobugcisa, ukuhanjiswa ngokukhawuleza.
UmgangathoIsiqinisekiso?Inkqubo yokulawula umgangatho ongqongqo.Izixhobo zobuchwephesha zokuhlalutya ziquka i-NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, njl.
Iisampulu?Uninzi lweemveliso zibonelela ngeesampulu zasimahla zokuvavanya umgangatho, iindleko zokuthumela kufuneka zihlawulwe ngabathengi.
Factory Audit?Uphicotho-zincwadi lwasefektri wamkelekile.Nceda wenze idinga kwangaphambili.
MOQ?Akukho MOQ.Umyalelo omncinci wamkelekile.
Ixesha lokuzisa? Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe.
Ezothutho?Nge-Express (FedEx, DHL), ngoMoya, ngoLwandle.
Amaxwebhu?Emva kwenkonzo yokuthengisa: I-COA, i-MOA, i-ROS, i-MSDS, njl.
Udibaniso lweSiko?Inokubonelela ngeenkonzo zesiko lokudibanisa ukuze zilungele iimfuno zakho zophando.
Immimiselo yokuhlawula?I-invoyisi yeProforma iya kuthunyelwa kuqala emva kokuqinisekiswa kwe-odolo, efakwe kwiinkcukacha zethu zebhanki.Intlawulo nge-T / T (i-Telex Transfer), i-PayPal, i-Western Union, njl.
| Iimpawu ezinobungozi | Xi - Uyacaphukisa |
| Iikhowudi zoMngcipheko | 36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumula kunye nesikhumba. |
| Inkcazelo yoKhuseleko | I-S24/25 - Gwema ukudibana nolusu kunye namehlo. S36 - Nxiba iimpahla ezifanelekileyo zokukhusela. S26 - Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango. |
| WGK eJamani | 3 |
| RTECS | VT8100000 |
| F | 3 |
| I-TSCA | Ewe |
| Ikhowudi ye-HS | 2922509099 |
I-L-Serine (i-H-Ser-OH; i-Ser efinyeziweyo okanye i-S) (i-CAS: i-56-45-1) i-amino acid, yenye ye-proteinogenic amino acids.Iicodon zayo kwikhowudi yezofuzo ziyi-UCU, i-UCC, i-UCA, i-UCG, i-AGU kunye ne-AGC.Ngenxa yeqela le-hydroxyl, i-serine ihlelwa njenge-polar amino acid.
Umsebenzi kunye nosetyenziso lwe-L-Serine Cas 56-45-1
1. I-L-Serine isetyenziswe njenge-reagent ye-biochemical kunye nezongezo zokutya;Isetyenziswe kuphando lwe-biochemical, ukulungiswa kwenkcubeko yentlangano, iyeza elisetyenziselwa i-amino acids kwiyeza lezondlo.
2. I-L-Serine isetyenziswa kwintsimi yamachiza, i-L-Serine isetyenziswa ngokubanzi ukuqwalasela isizukulwana sesithathu sokufakela i-amino acid kunye ne-nutritionalbsupplements, kunye nokudityaniswa kweentlobo ze-amino acid ze-silika, ezifana ne-cardiovascular, umhlaza, i-AIDS kunye ne-genetic. ubunjineli bamachiza amatsha kunye nezinye ii-amino acids ezikhuselweyo.Ukutya kunye nesiselo Field, L-Serine ingasetyenziselwa iziselo ezemidlalo, amino acids iziselo ukutya.Intsimi yokutya, i-L-Serine ingasetyenziselwa ukutya kwezilwanyana, ukukhuthaza ukukhula kwezilwanyana kunye nophuhliso;
3. I-L-Serine isetyenziswa njengesongezelelo seSondlo, kwizithambiso njengesongezo sesondlo solusu.
4. Ifumaneka ngeenjongo zophando lwe-biochemical kunye nesondlo, kodwa ingasetyenziswa njenge-synthetic ring serine ekrwada.
5. I-L-Serine inoluhlu olubanzi lokusetyenziswa kweyeza.I-Serine ikhuthaza i-metabolism yamafutha kunye ne-fatty acids kwaye inceda ukugcina amajoni omzimba.
6. I-L-Serine iphinda isetyenziswe njengesongezelelo sokutya apho inokunceda ukuphucula umsebenzi wememori kunye nemveliso yokunyamekela komntu apho inceda ukuveliswa kweeseli ezintsha zesikhumba.
7. I-L-Serine isetyenziswe ekulungiseleleni i-Tris-BSAN buffer ye-homogenization.Ikwasetyenziselwa uhlalutyo lobungakanani be-polypeptides kumchamo oqhelekileyo.
8. I-L-Serine isetyenziselwa ukuhlanganiswa kwe-purines kunye ne-pyrimidines njenge-antibacterial / antifungal agents, kunye nokusebenza njenge-proteinogenic compound.
9. I-L-Serine ihlelwa njenge-amino acid engabalulekanga.Isetyenziswa njengecandelo lemidiya yenkcubeko yeseli kunye nemathiriyeli ekrwada kwintengiso yebhayoloji yeeproteni eziphinda ziphinde ziphinde zonyango kunye ne-monoclonal antibodies.
10. I-L-Serine ngokusebenzisa i-phosphorylation-hydroxy derivative inokukhutshwa emva kwemisebenzi ebalulekileyo ye-physiological ye-P serine inxalenye enkulu ye-phospholipids;
11. I-L-Serine enexabiso elizinzile le-pH yendima ye-eye drops, i-eye drops kunye ne-non-irriting;
12. I-L-Serine yinto ebalulekileyo yendalo yokuthambisa (i-NMF) yenye ye-stratum corneum yokugcina indima ephambili yamanzi, i-L-Serine iyisitshixo kwii-additives eziphuculweyo ze-cosmetic.
