L-Thyroxine CAS 51-48-9 Ubunyulu > 98.0% (HPLC)

Inkcazelo emfutshane:

Igama leMichiza: L-Thyroxine

Izithethantonye: Levothyroxine;L-T4

CAS: 51-48-9

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Umgubo weCrystalline oMhlophe okanye oMhlophe

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Iimveliso ezinxulumeneyo

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Inkcazo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-L-Thyroxine (i-CAS: 51-48-9) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza L-Thyroxine
Izithethantonye Levothyroxine;L-T4;I-NSC 36397;(-)-Thyroxine;3,3',5,5'-Tetraiodo-L-Thyronine;3,5,3',5'-Tetraiodothyronine;i-beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]alanine;β-((3,5-Diiodo-4-Hydroxyphenoxy) -3,5-Diiodophenyl)alanine;o-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine
Inombolo yeCAS 51-48-9
Inombolo yeCAT RF2891
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli C15H11I4NO4
Ubunzima beMolekyuli 776.87
Indawo yokunyibilika 227.0 ~ 230.0℃
Indawo yokubilisa 576.3±50.0℃
Ukuxinana 2.635
Inovakalelo Ukukhanya okunovelwano
Ukunyibilika kwamanzi Ayinyibilikiyo emanzini
Ukunyibilika Ichithwa kwi-4M i-Ammonium Hydroxide kwi-Methanol kwi-50mg / ml
Uzinzo ≥ Iminyaka emi-2
Ikhowudi ye-HS 29379000
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umgubo weCrystalline oMhlophe okanye oMhlophe
Ubunyulu / Indlela yokuHlalutya >98.0% (HPLC)
Indawo yokunyibilika 227.0 ~ 230.0℃
Ukujikeleziswa okuthe ngqo [α]20/D -5.2°~ -6.2° (C=1, I-Ethanol: 1N NaOH=2:1)
Iintsimbi ezinzima (Pb) ≤10ppm
Ilahleko ekomisweni <0.20%
Intsalela kwi-Ignition <0.10%
Ukungcola ngokupheleleyo <1.50%
I-Infrared Spectrum Iyahambelana neSakhiwo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa AbaPhakathi bamayeza

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Isicelo:

I-L-Thyroxine (i-CAS: i-51-48-9) okanye i-Levothyroxine yi-hormone ye-thyroid yokwenziwa efana neekhemikhali ezifana ne-thyroxine (T4), eyenziwa ngokwemvelo ngeeseli ze-follicular ze-thyroid gland.Isetyenziselwa ukunyanga ukunqongophala kwehomoni ye-thyroid, kwaye ngamanye amaxesha ukuthintela ukuphindaphinda komhlaza we-thyroid.Njengomlingani wayo ofihliweyo ngokwemvelo, iLevothyroxine yikhompawundi ye-chiral kwi-L-form.Ichiza elinxulumeneyo i-dextrothyroxine (D-Thyroxine) lalisetyenziswa kwixesha elidlulileyo njengonyango lwe-hypercholesterolemia (amanqanaba aphezulu e-cholesterol) kodwa yarhoxiswa ngenxa yeziphumo ebezingalindelekanga zentliziyo.I-L-Thyroxine isetyenziselwa kakhulu unyango lwe-hypothyroidism, i-goiter, i-lymphocytic thyroiditis engapheliyo, i-myxedema coma, kunye ne-stupor.Kwi-vivo, i-L-Thyroxine (i-0.9 kunye ne-2.7 μg) inqanda ukuhlanganiswa kunye nokukhululwa kwe-thyrotropin eyenziwa yi-hormone ekhupha i-thyrotropin kwi-pituitary yangaphambili kwiigundane.Iifomyula eziqukethe i-L-Thyroxine zisetyenziswe kunyango lwe-hypothyroidism.Unyango lwe-Levothyroxine lusetyenziswa kwimeko yokunqongophala kwehomoni yegilo kumzimba womntu, njengoko kwenzeka phantsi kwe-thyroid, i-pituitary kunye ne-hypothalamic glands (ngokulandelelanayo, i-hypothyroidism yokuqala, yesibini kunye neyesithathu).I-L-Thyroxine ikwasetyenziswa kunyango lwe-euthyroid goiter kunye ne-multinodular goiter, kubandakanywa amaqhuqhuva e-thyroid, i-subacute okanye i-thyroiditis engapheliyo, okanye kwimeko yokusilela emva kotyando, okanye emva konyango lwe-radiometabolic kwizigulana ezinomhlaza we-thyroid.Iziphumo zeli chiza zixhomekeke kakhulu kwidosi.Kwiidosi ezincinci, i-L-Thyroxine ibonisa isenzo se-anabolic.Kwidosi ephakathi, ikhuthaza ukukhula kunye nophuhliso lwezicubu, i-metabolism yeprotheyini, amafutha, kunye neekhabhohayidrethi, inyusa umsebenzi osebenzayo we-nervous kunye ne-cardiovascular system, kunye nezintso kunye nesibindi.Kwimilinganiselo emikhulu, iyancipha umsebenzi we-thyrotropic we-hypophysis kwaye icinezela imveliso ye-thyroid gland.

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