Lenvatinib Mesylate Intermediate CAS 205448-65-3 Ubunyulu > 98.0% (HPLC) Factory

Inkcazelo emfutshane:

Igama leMichiza: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

CAS: 205448-65-3

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Okumhlophe-Kumhlophe ukuya kwiPowder etyheli

Umbindi weLenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Lenvatinib Mesylate Intermediate with High Purity
Lenvatinib Mesylate CAS 857890-39-2
I-4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
I-Desquinolinyl Lenvatinib;I-1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
I-4-Amino-3-Chlorophenol CAS 17609-80-2
I-4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Iipropati zeMichiza:

Igama leMchiza	I-Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
Izithethantonye	I-1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;ILenvatinib ePhakathi 3
Inombolo yeCAS	205448-65-3
Inombolo yeCAT	RF-PI1973
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ye-50 MT / Year
Ifomula yeemolekyuli	C12H11NO4
Ubunzima beMolekyuli	233.22
Indawo yokubilisa	421.0±45.0℃
Ukuxinana	1.267±0.060 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	I-Off-White ukuya kwiPowder etyheli
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)
Ilahleko ekomisweni	<1.00%
Intsalela kwi-Ignition	<0.50%
Ukungcola ngokupheleleyo	<2.00%
H-NMR	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	AbaPhakathi bamayeza

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) iphakathi kweLenvatinib Mesylate (CAS: 857890-39-2).I-Lenvatinib, ethengiswa phantsi kwegama le-brand Lenvima phakathi kwabanye, liyeza elichasayo lomhlaza kunyango lweentlobo ezithile zomhlaza wegilo kunye neminye imihlaza ngokunjalo.Yaphuhliswa ngu-Eisai Co. kwaye isebenza njenge-multiple kinase inhibitor ngokuchasene ne-VEGFR1, VEGFR2 kunye ne-VEGFR3 kinases.I-Lenvatinib ivunyiwe (ukususela kwi-2015) yonyango lomhlaza we-thyroid owahlukileyo onokuthi ubuyele kwindawo okanye i-metastatic, i-progressive, kwaye ayizange iphendule unyango nge-iodine ye-radioactive (i-radioiodine).NgoMeyi ka-2016, i-US Food and Drug Administration (i-FDA) yavuma (ngokudityaniswa ne-everolimus) kunyango lwe-renal cell carcinoma ehamba phambili elandela unyango olunye lwangaphambili oluchasene ne-angiogenic.Iyeza likwavunyiwe e-US nakwiManyano yaseYurophu ye-hepatocellular carcinoma engenakususwa ngotyando kwizigulana ezingakhange zifumane unyango lomhlaza ngomlomo okanye ngenaliti.