Levosimendan Intermediate CAS 36725-28-7 Ubunyulu >99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone (CAS: 36725-28-7) with high quality, commercial production. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com
Igama leMchiza | 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone |
Izithethantonye | I-6-(p-Aminophenyl) -5-methyl-4,5-dihydro-3 (2H) -pyridazinone;I-1,4-Dihydro-4-Methyl-3- (4-Aminophenyl) pyridazine-6 (5H) -enye;Ukungcola kweLevosimendan 5 |
Inombolo yeCAS | 36725-28-7 |
Inombolo yeCAT | RF-PI1976 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C11H13N3O |
Ubunzima beMolekyuli | 203.25 |
Indawo yokunyibilika | 194.0 ukuya 198.0℃ |
Ukuxinana | 1.30±0.10 g/cm3 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | I-Off-White ukuya kwiPale Brownish Color Powder |
Ukuchongwa (HPLC) | I-HPLC RT yencopho enkulu ihambelana naleyo yomgangatho wokusebenza wangaphakathi |
Ilahleko ekomisweni | <0.50% |
Intsalela kwi-Ignition | <0.20% |
Izinto ezinxulumeneyo | (HPLC) |
Ukungacoceki Okukodwa | <0.20% |
Ukungcola ngokupheleleyo | <0.50% |
Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) |
Iintsimbi ezinzima | <20ppm |
Proton NMR Spectrum | Iyahambelana noLwakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi weLevosimendan (CAS: 141505-33-1) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
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I-6-(4-Aminophenyl) -4,5-Dihydro-5-Methyl-3 (2H)-Pyridazinone (CAS: 36725-28-7) iphakathi kweLevosimendan (CAS: 141505-33-1).I-Levosimendan yaziswa eSweden njenge-iv infusion yonyango lwe-acute heart failure okanye iimpawu eziphikisayo zokungaphumeleli kwentliziyo engapheliyo kwiimeko apho unyango oluqhelekileyo (umzekelo, i-diuretic okanye i-ACE inhibitor) ayanele.Iphinde isebenze i-ventricular and arterial adenostne triphosphate-regulated potassium channels ezibangela i-vasodilatation kwi-vascular smooth muscle kwaye ikhusela i-myocardium kwi-infarction.Umsebenzi wayo ophantsi we-phosphodiesterase III wokuthintela mhlawumbi awunaxanduva lwe-inotropic emihle, i-lusitropic kunye ne-dilating effects.Ngokungafaniyo nezinye izidakamizwa ze-cardiotonic, i-levosimendan iyakwazi ukuvelisa iziphumo ezilungileyo ze-inotropic ngaphandle kokwandisa ukuphumla kwe-myocardial okanye ukwandisa iziganeko ze-arrythmias enobungozi.Kuye kwaboniswa ngokweklinikhi ukuba kunomngcipheko ophantsi wokufa kwizigulane ezinokuphelelwa yintliziyo xa kuthelekiswa ne-placebo kunye ne-dobutamine.Kuba inamandla amakhulu, i-levosimendan okwangoku iphantsi kovavanyo olongezelelweyo lweklinikhi njengonyango olungapheliyo lokusilela kwentliziyo.
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