Levosimendan Intermediate CAS 36725-28-7 Ubunyulu >99.5% (HPLC) Factory

Inkcazelo emfutshane:

Igama leMichiza: 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone

CAS: 36725-28-7

Ubunyulu: >99.5% (HPLC)

Imbonakalo: Okumhlophe-kuMhlophe ukuya kwiPowder yoMbala oPale

Umbindi weLevosimendan (CAS: 141505-33-1)

Umgangatho ophezulu, iMveliso yoRhwebo

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone (CAS: 36725-28-7) with high quality, commercial production. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone
Izithethantonye	I-6-(p-Aminophenyl) -5-methyl-4,5-dihydro-3 (2H) -pyridazinone;I-1,4-Dihydro-4-Methyl-3- (4-Aminophenyl) pyridazine-6 (5H) -enye;Ukungcola kweLevosimendan 5
Inombolo yeCAS	36725-28-7
Inombolo yeCAT	RF-PI1976
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C11H13N3O
Ubunzima beMolekyuli	203.25
Indawo yokunyibilika	194.0 ukuya 198.0℃
Ukuxinana	1.30±0.10 g/cm3
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	I-Off-White ukuya kwiPale Brownish Color Powder
Ukuchongwa (HPLC)	I-HPLC RT yencopho enkulu ihambelana naleyo yomgangatho wokusebenza wangaphakathi
Ilahleko ekomisweni	<0.50%
Intsalela kwi-Ignition	<0.20%
Izinto ezinxulumeneyo	(HPLC)
Ukungacoceki Okukodwa	<0.20%
Ukungcola ngokupheleleyo	<0.50%
Ubunyulu / Indlela yokuHlalutya	>99.5% (HPLC)
Iintsimbi ezinzima	<20ppm
Proton NMR Spectrum	Iyahambelana noLwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weLevosimendan (CAS: 141505-33-1)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-6-(4-Aminophenyl) -4,5-Dihydro-5-Methyl-3 (2H)-Pyridazinone (CAS: 36725-28-7) iphakathi kweLevosimendan (CAS: 141505-33-1).I-Levosimendan yaziswa eSweden njenge-iv infusion yonyango lwe-acute heart failure okanye iimpawu eziphikisayo zokungaphumeleli kwentliziyo engapheliyo kwiimeko apho unyango oluqhelekileyo (umzekelo, i-diuretic okanye i-ACE inhibitor) ayanele.Iphinde isebenze i-ventricular and arterial adenostne triphosphate-regulated potassium channels ezibangela i-vasodilatation kwi-vascular smooth muscle kwaye ikhusela i-myocardium kwi-infarction.Umsebenzi wayo ophantsi we-phosphodiesterase III wokuthintela mhlawumbi awunaxanduva lwe-inotropic emihle, i-lusitropic kunye ne-dilating effects.Ngokungafaniyo nezinye izidakamizwa ze-cardiotonic, i-levosimendan iyakwazi ukuvelisa iziphumo ezilungileyo ze-inotropic ngaphandle kokwandisa ukuphumla kwe-myocardial okanye ukwandisa iziganeko ze-arrythmias enobungozi.Kuye kwaboniswa ngokweklinikhi ukuba kunomngcipheko ophantsi wokufa kwizigulane ezinokuphelelwa yintliziyo xa kuthelekiswa ne-placebo kunye ne-dobutamine.Kuba inamandla amakhulu, i-levosimendan okwangoku iphantsi kovavanyo olongezelelweyo lweklinikhi njengonyango olungapheliyo lokusilela kwentliziyo.