Luliconazole CAS 187164-19-8 Ubunyulu ≥99.0% HPLC Factory API High Quality
Ukubonelela ngeLuliconazole kunye nabaPhakathi abaNxulumeneyo
Luliconazole CAS 187164-19-8
(1-Imidazolyl)acetonitrile CAS 98873-55-3
(S) -2,4-Dichloro-α-(Chloromethyl)benzyl Utywala CAS 126534-31-4
| Igama leMchiza | Luliconazole |
| Izithethantonye | (2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile;NND 502 |
| Inombolo yeCAS | 187164-19-8 |
| Inombolo yeCAT | RF-API110 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | I-C14H9Cl2N3S2 |
| Ubunzima beMolekyuli | 354.27 |
| Indawo yokunyibilika | 150.0 ukuba 154.0℃ |
| Ujikelezo oluKhethekileyo [a]20/D | -48.0 ° ukuya -53.0 ° (C=1, DMF) |
| Ukunyibilika | Ukunganyibiliki emanzini;Inyibilika kwi-acetone;Inyibilika kancinane kwiMethanol |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Okumhlophe-kuMhlophe ukuya kuMthubi wePowder oyiCrystalline oKhanyayo |
| Ukuchongwa kwe-IR | I-spectrum ye-infrared yesampuli kufuneka ihambelane naleyo yomgangatho wereferensi |
| Ukuchongwa kwe-HPLC | Ixesha lokugcinwa kwencopho enkulu yesisombululo sesampulu kufuneka ihambelane nesisombululo esisemgangathweni njengoko sifunyenwe kuvavanyo |
| Ilahleko ekomisweni | ≤0.50% |
| Intsalela kwi-Ignition | ≤0.20% |
| Iintsimbi ezinzima (Pb) | ≤20ppm |
| Izinto ezinxulumeneyo | |
| Nakuphi na Ukungacoceki komntu | ≤0.20% |
| Ukungcola ngokupheleleyo | ≤0.50% |
| Izinyibilikisi ezishiyekileyo | |
| IMethanol | ≤3000ppm |
| Acetonitrile | ≤410ppm |
| Dichloromethane | ≤600ppm |
| N-Hexane | ≤290ppm |
| I-Ethyl Acetate | ≤5000ppm |
| Tetrahydrofuran | ≤720ppm |
| I-Methyl tert-Butyl Ether | ≤5000ppm |
| N-Heptane | ≤5000ppm |
| I-Triethylamine | ≤320ppm |
| I-Dimethyl Sulfoxide | ≤5000ppm |
| Ubunyulu / Indlela yokuHlalutya | ≥99.0% (HPLC) (kwisiseko esomileyo) |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | AbaPhakathi bamayeza |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-Luliconazole (i-CAS: 187164-19-8) yintsholongwane ye-antifungal imidazole ene-spectrum ebanzi kunye nomsebenzi onamandla we-antifungal.I-Luliconazole luhlobo lwe-analogue ye-lanoconazole.Inokuphazamisa ukudityaniswa kodonga lweseli lomngundo kunye nokukhula komngundo ngokuncipha kwamanqanaba eergosterol ngokuthintela umsebenzi we-lanosterol demethylase.Ngaphandle kokuba isetyenziselwa unyango lonyawo lomdlali, i-jock itch kunye ne-ringworm, iye yaphuhliswa kunyango lwe-onychomycosis (i-nail fungus) kwaye ngoku sele ingene kwisigaba sezonyango III.Le mveliso yaphuhliswa ekuqaleni yi-Japan pesticide Corporation (NihonNohyaku Co., Ltd.).NgoNovemba ka-2013, i-FDA iphumeze i-1% ye-luliconazole cream yokungena kwimarike yonyango lwe-topical yonyawo lomdlali we-interdigital, i-jock itch kunye ne-ringworm enegama lezorhwebo elithi Luzu kwaye yaqala ukungena kwimarike eMntla Melika.Kwangoko ngo-Epreli ka-2005, i-luliconazole yayivunyiwe ukuba ingene kwimarike eJapan phantsi kwegama lorhwebo elithi Lulicon.NgoJanuwari 2010 kunye noJuni 2012, yavunywa ukuba ithengiswe eIndiya naseTshayina, ngokulandelanayo.
