Moc-L-Tert-Leucine CAS 162537-11-3 Ubunyulu ≥99.0% (HPLC) Atazanavir Intermediate Factory
Ubonelelo lwabavelisi ngoBusulungekileyo obuPhezulu kunye noMgangatho oZinzileyo
Igama leMichiza: Moc-L-Tert-Leucine
CAS: 162537-11-3
Umbindi we-Atazanavir HIV-1 Protease Inhibitor
Umgangatho ophezulu, iMveliso yoRhwebo
Igama leMchiza | Moc-L-Tert-Leucine |
Izithethantonye | I-Methoxycarbonyl-L-tert-Leucine;N-(Methoxycarbonyl)-tert-Leucine;I-Atazanavir eNxulumene neKhowudi A |
Inombolo yeCAS | 162537-11-3 |
Inombolo yeCAT | RF-PI289 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C8H15NO4 |
Ubunzima beMolekyuli | 189.21 |
Indawo yokunyibilika | 109℃ |
Ukuxinana | 1.126 g/cm3 |
Indawo yokubilisa | 320.9℃ ku-760 mmHg |
Ukunyibilika | Inyibilika kwi-Ethyl Acetate kunye neMethanol |
Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Iikristale eziMhlophe ukuya kwezingaMhlophe |
Iindlela zokuchongwa | HPLC |
Indlela yokuhlanjululwa / yoHlalutya | ≥99.0% (HPLC) |
Moc-L-Tle-Tle-OH | ≤0.30% |
L-Moc-Dimer | ≤0.30% |
L-Tle-OH | ≤0.10% |
I-Methoxycarbonyl-L-Valine | ≤0.10% |
N-Acetyl-L-tert-Leucine | ≤0.05% |
Ukungacoceki komntu Okungaziwayo | ≤0.30% |
Ukungcola ngokupheleleyo | ≤1.0% |
Isiqulatho se-Enantiomer | ≤0.10% (NguChiral HPLC) |
Isiqulatho samanzi | ≤0.50% (Nge-KF) |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.20% |
Iintsimbi ezinzima | ≤10ppm |
Ukusetyenziswa | I-Amino Acid;Umbindi we-Atazanavir (CAS 198904-31-3) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma.
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-Moc-L-Tert-Leucine (i-CAS 162537-11-3) enomgangatho ophezulu.I-Moc-L-Tert-Leucine luhlobo lwe-amino acid ephuma kuyo.Iluncedo kakhulu eliphakathi kwi-synthesis esebenzayo ye-HIV protease inhibitor Atazanavir (CAS 198904-31-3) kunye ne-Atazanavir sulfate (CAS 229975-97-7).
I-Atazanavir yi-arhente ye-antiretroviral evunywe yi-FDA ukuba isetyenziswe kunye nezinye ii-anti-RTagents kunyango losulelo lwe-HIV.Ichiza lihlala lisetyenziswa ngokudibeneyo ne-RT inhibitors.I-Atazanavir sisithinteli se-HIV-1 protease (EC50=2.6 nM).Kwiiseli ezizimeleyo, inezongezelelo kwiziphumo ze-antiviral synergistic ephakathi xa idityaniswe namanye amachiza e-antiretroviral.Ngenxa yoko, iqhele ukusetyenziswa kwi-vivo kunyango oludityanisiweyo losulelo lwe-HIV-1.