N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Uvavanyo 98.5 ~ 101.0% Umgangatho ophezulu weFactory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) kunye nomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-amino acids kunye nezinto eziphuma kuzo.Ngenxa yomgangatho wemveliso ogqwesileyo, amaxabiso afanelekileyo, siye safumana igama elihle kunye nokuthenjwa kubathengi bethu basekhaya nabaphesheya.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kwi-N-Acetyl-L-Cysteine,Please contact: alvin@ruifuchem.com
| Igama leMchiza | N-Acetyl-L-Cysteine |
| Izithethantonye | I-Ac-Cys-OH;iAcetylcysteine;I-NAC;I-LNAC;N-Acetylcysteine;N-Acetyl-3-Mercaptoalanine;Acetyl-Laevo-Cysteine |
| Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezingama-50 ngenyanga |
| Inombolo yeCAS | 616-91-1 |
| Ifomula yeemolekyuli | C5H9NO3S |
| Ubunzima beMolekyuli | 163.19 |
| Indawo yokunyibilika | 106.0~108.0℃(lit.) |
| Inovakalelo | Ubuthathaka bomoya |
| Ukunyibilika kwamanzi | Inyibilika Emanzini, Phantse Ukungafihli |
| Ukunyibilika | Inyibilika kwi-Ethanol, iMethanol, utywala.Ayinyibiliki kwi-Ether |
| Ugcino Temp. | Itywinwe kwindawo eyomileyo, iVenkile kwindawo yobushushu beGumbi |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Ukuhlelwa | Amino Acids & Derivatives |
| Uphawu | Ruifu Chemical |
| Iingxelo zoMngcipheko | 36/37/38 - Ukucaphukisa emehlweni, inkqubo yokuphefumula kunye nesikhumba. |
| Iingxelo zoKhuseleko | S22 - Musa ukuphefumla uthuli.I-S24/25 - Gwema ukudibana nolusu kunye namehlo. |
| WGK eJamani | 3 |
| RTECS | HA1660000 |
| F | 10-23 |
| I-TSCA | Ewe |
| Ikhowudi ye-HS | 2922491990 |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Iikristale eziMhlophe okanye iPowder yeCrystalline;I-Acid Taste kakhulu | Iyahambelana |
| Ukuchongwa | I-Infrared Absorption Spectrum | Iyahambelana |
| Ukujikeleziswa okuthe ngqo [α]20/D | +21.3° ukuya +27.0° (C=5 kwi-Phosphate Buffered Saline) | +23,5 ° |
| Imeko yesisombululo (iTransmittance) | Icacile kwaye ayinaMbala ≥98.0% | 99.0% |
| Ikloridi (Cl) | ≤0.040% | <0.040% |
| Isulfate (SO4) | ≤0.030% | <0.030% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Intsimbi (Fe) | ≤20ppm | <20ppm |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
| IZinc (Zn) | ≤10ppm | <10ppm |
| IArsenic (As2O3) | ≤1.0ppm | <1.0ppm |
| Izinto ezinxulumeneyo | (Indlela ye-HPLC) | |
| L-cystine | ≤0.50% | Iyahambelana |
| L-Cysteine | ≤0.50% | Iyahambelana |
| N,N'-Diacetyl-L-Cystine | ≤0.50% | Iyahambelana |
| N,S-Diacetyl-L-Cysteine | ≤0.50% | Iyahambelana |
| Ukungcola omnye komnye | ≤0.50% | Iyahambelana |
| Ukungcola ngokupheleleyo | ≤0.50% | Iyahambelana |
| Ilahleko ekomisweni | ≤0.50% | 0.20% |
| Intsalela ekutshisweni (iSulfated) | ≤0.20% | 0.05% |
| Isivavanyi | 98.5 ukuya kwi-101.0% (kwiSisekelo esomileyo) | 99.90% |
| Ixabiso le-pH | 2.0 ukuya ku-2.8 (1.0g kwi-100ml ye-H2O) | 2.5 |
| Ubutyhefu be-Biochemical | Ukupasa | Ukupasa |
| Izinto eziphilayo eziguquguqukayo | Dlula | Dlula |
| Ukufunyanwa kwe-Endonuclease | ≤0.1 EU/g | <0.1 EU/g |
| Ukuqukumbela | Le Mveliso ngokuHlolwa ngokuVumelana noMgangatho we-AJI97 | |
| Usetyenziso oluphambili | IiAmino Acids;Izongezo zokutya;AbaPhakathi bamayeza | |
Iphakheji: Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) AJI97 Indlela yoVavanyo
I-N-Acetyl-L-Cysteine, xa yomisiwe, iqulethe ngaphantsi kweepesenti ze-98.5 kwaye ingabi ngaphezu kweepesenti ze-101.0 ze-N-Acetyl-L-Cysteine (C5H9NO3S).
inkcazelo: Iikristale ezimhlophe okanye umgubo crystalline, incasa kakhulu acid.
Inyibilika simahla emanzini, inyibilika kwi-ethanol, ayinyibiliki kwi-ether.
Ukunyibilika (H2O, g/100g): 17 (20℃), 80 (40℃), 260 (60℃)
Ukuchonga: Thelekisa i-spectrum ye-infrared yokufunxa yesampuli kunye neyomgangatho we-potassium bromide disc method.
Ukujikeleziswa okuthe ngqo [α]20/D: Isampulu eyomileyo, C=8, isisombululo se-phosphate buffer
Imeko yeSolution (Transmittance): 0.5g kwi-10ml ye-H2O, i-spectrophotometer, i-430nm, i-10mm ubukhulu beeseli.
Iintsimbi ezinzima (Pb): 2.0g, (1), ref: 2.0ml yePb Std.(0.01mg/ml)
I-Zinc (Zn): Indlela yokufunxa i-athomu
Izinto ezinxulumeneyo: Indlela ye-HPLC
Ilahleko ekomisweni: Kwivacuum, kwi-70℃ iiyure ezi-4
Intsalela kwi-Ignition (Sulfated): Uvavanyo lwe-AJI 13
Uvavanyo: Isampulu eyomileyo, 200mg, 0.05mol/L I2 1ml=16.320mg C5H9NO3S
pH: 1.0g kwi-100ml ye-H2O
Umda kunye nemeko yogcino ecetyiswayo: Izikhongozeli ezigciniweyo eziqinileyo kubushushu obulawulwayo begumbi (unyaka omnye).
I-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) Indlela yokuvavanya i-USP35
INGCACISO
I-Acetylcysteine iqulethe i-NLT 98.0% kunye ne-NMT 102.0% ye-L-threonine (C5H9NO3S), ibalwe ngesiseko esomileyo.
UKUCHAZA
A. UKUFUTSHWA KWE-IFRARED <197K>
UVAVANYO
INKQUBO
Isigaba seselula: 6.8 g / L ye-monobasic potassium phosphate.Lungisa nge-asidi ye-phosphoric ukuya kwi-pH ye-3.0.
Isisombululo se-sodium metabisulfite: 0.5 mg / mL ye-sodium metabisulfite emanzini, esanda kulungiswa
Isisombululo somgangatho wangaphakathi: 5 mg/mL ye-USP L-Phenylalanine RS kwisisombululo seSodium metabisulfite
Isisombululo sesitokhwe esisemgangathweni: 10 mg/mL ye-USP Acetylcysteine RS kwisisombululo seSodium metabisulfite
Isisombululo esisemgangathweni: i-0.5 mg / mL ye-USP i-Acetylcysteine RS kunye ne-0.25 mg / mL ye-USP L-Phenylalanine RS kwisisombululo se-Sodium metabisulfite ukusuka kwisisombululo seSitokhwe esiPhambili kunye nesisombululo sangaphakathi sangaphakathi
Isampuli yesisombululo sesitokhwe: 10 mg/mL ye-Acetylcysteine kwisisombululo seSodium metabisulfite
Isisombululo sesampuli: 0.5 mg / mL ye-Acetylcysteine kunye ne-0.25mg / mL ye-USP L-Phenylalanine RS kwisisombululo se-Sodium metabisulfite kwisisombululo seSample stock kunye nesisombululo sangaphakathi sangaphakathi
Inkqubo yeChromatographic
(Jonga iChromatography <621>, Ukufaneleka kweNkqubo.)
Indlela: LC
Umtshina: UV 214 nm
Ikholamu: 3.9-mm × 30-cm;ukupakisha L1
Izinga lokuhamba: 1.5 mL / min
Ubungakanani betofu: 5 µL
Ukufaneleka kwenkqubo
[QAPHELA-Amaxesha anxulumeneyo okugcina i-acetylcysteine kunye ne-L-phenylalanine amalunga ne-0.5 kunye ne-1.0, ngokulandelelanayo.]
Iimfuno zokufaneleka
Isisombululo: I-NLT 6 phakathi kwe-acetylcysteine kunye ne-L-phenylalanine
Ukutenxa komgangatho ozalanayo: NMT 2.0%
Uhlalutyo
Iisampulu: Isisombululo esisemgangathweni kunye nesisombululo seSampuli
Bala ipesenti ye-acetylcysteine (C5H9NO3S) kwisahlulo se-Acetylcysteine ethathiweyo:
Isiphumo = (RU/RS) × (CS/CU) × 100
I-RU = i-peak response ratio ye-acetylcysteine ukuya kwi-L-phenylalanine kwisisombululo seSampuli
I-RS = i-peak response ratio ye-acetylcysteine ukuya kwi-L-phenylalanine ukusuka kwisisombululo esiPhakathi
CS = ukuxinwa kwe-USP Acetylcysteine RS kwisisombululo esiPhakathi (mg / mL)
I-CU = ukuxinwa kwe-acetylcysteine kwisisombululo seSampule (mg / mL)
Indlela yokwamkela: 98.0% -102.0% kwisiseko esomileyo
UBUNGCOLA
INTSALELA YOKUBASE <281>: NMT 0.5%
IIMETALI EZININZI, Indlela II <231>
[ISILUMKO-Zilolonge ngenxa yogqabhuko-dubulo.]
Uhlalutyo: Ngendlela eyehlayo, manzisa isampuli nge-2 mL ye-nitric acid, kwaye uqhubeke njengoko kuyalelwe ukulungiselela uVavanyo.
Indlela yolwamkelo: NMT 10 ppm
IIMVAVANYO EZITHILE
UKUJONGANA KOMBONISO, Ukujikeleza okuthe ngqo <781S>
Isithinteli: Xuba i-29.5 mL ye-1 N sodium hydroxide, i-50 mL ye-1 M monobasic potassium phosphate, kunye namanzi aneleyo ukwenza i-100 mL.Lungisa kwi-pH ye-7.0 ± 0.1 ngokudibanisa nasiphi isisombululo, njengoko kuyimfuneko.
Isisombululo sesampuli: Kwi-flask ye-volumetric ye-25-mL, xuba i-1.25 g kunye ne-1 mL yesisombululo se-edetate disodium (1 kwi-100), yongeza i-7.5mL yesisombululo se-sodium hydroxide (1 kwi-25), kwaye udibanise ukunyibilika.Nciphisa nge-Buffer ukuya kwivolumu.
Indlela yokwamkela: +21 ° ukuya +27 °
pH <791>: 2.0-2.8 kwisisombululo (1 kwi-100)
UKULAHLEKO EKOMISENI <731>: Yomisa isampulu kuxinzelelo olumalunga ne-50 mm yemer cury kwi-70° nge-4 h: ilahlekelwa yi-NMT 1.0% yobunzima bayo.
IIMFUNO EZONGEZELELWEYO
UKUPAKISHWA NOKUGCINA: Zigcine kwizikhongozeli eziqinileyo, kwaye uzigcine kwindawo yobushushu obulawulwayo begumbi.
IMIGANGATHO YE-USP REFERENCE <11>
USP Acetylcysteine RS
USP L-Phenylalanine RS
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Umsebenzi kunye nesicelo se-N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) powder
1. I-N-Acetyl-L-Cysteine, eyaziwa ngokuba yi-N-Acetylcysteine okanye i-Acetylcysteine (NAC), iyiyeza leyeza kunye nesondlo esisetyenziswa ngokuyinhloko njenge-agent ye-mucolytic kunye nokulawulwa kwe-paracetamol (acetaminophen) overdose.Olunye usetyenziso lubandakanya ukuphindaphinda kwe-sulfate kwiimeko, ezifana ne-autism, apho i-cysteine kunye ne-amino acids enxulumene nesulfure inokupheliswa.
2. I-N-Acetyl-L-Cysteine yi-derivative ye-cysteine apho iqela le-acetyl lifakwe kwi-athomu ye-nitrogen.Le khompawundi ithengiswa njengesongezelelo sokutya esihlala sibanga i-antioxidant kunye neziphumo zokukhusela isibindi.Isetyenziswa njengeyeza lokhohlokhohlo kuba iqhawula amaqhina e-disulfide kwi-mucus kwaye iyinyibilikise, yenze kube lula ukukhohlela.Ikwasisenzo sokwaphula iibhondi ze-disulfide esenza ukuba ibe luncedo ekunciphiseni i-mucus engqindilili ngokungaqhelekanga kwizigulana ze-cystic kunye ne-pulmonary fibrosis.
3. I-Acetylcysteine yi-agent ye-mucolytic enefuthe elinamandla le-mucolytic.Iqela le-sulfhydryl eliqulethwe kwimolekyuli linokwaphula ibhondi ye-disulfide kwitsheyini ye-glycoprotein polypeptide kwisikhohlela, ngaloo ndlela inciphisa i-viscosity yesikhohlela, kwaye yenze ulwelo lwesikhohlela kwaye kube lula ukukhohlela.Le mveliso inokuphinda iphule imicu ye-DNA kwi-sputum ye-purulent, ngoko ayikwazi ukunyibilika kuphela i-sputum emhlophe, kodwa kunye ne-sputum ye-purulent.Kwizigulane ezine-expectorants jikelele zingasebenziyo, le mveliso isenokuthi isebenze.
4. Isetyenziswa njengeyeza lokunyibilikisa i-phlegm.Isetyenziselwa uphando lwe-biochemical kunye neyeza njenge-antidote ye-phlegm kunye ne-acetaminophen poisoning.I-biochemical reagent, iyeza, le mveliso isetyenziswa njenge-expectorant, yathi i-phlegm kulula ukuyicoca.
5. Iziphumo ebezingalindelekanga eziqhelekileyo ziquka isicaphucaphu kunye nokugabha xa uthathwa ngomlomo. Ulusu ngamanye amaxesha lunokuba bomvu kwaye lurhawuzelelwe nangaluphi na uhlobo.Uhlobo olungakhuselekanga lwe-anaphylaxis lusenokwenzeka.Kubonakala kukhuselekile ekukhulelweni.I-paracetamol overdose, isebenza ngokunyusa izinga le-glutathione, i-antioxidant enokunciphisa imveliso ye-toxic breakdown ye-paracetamol.Xa ifakwe, isebenza njenge-mucolytic ngokunciphisa ubukhulu be-mucus.
6. I-Acetylcysteine yaqala ukunikwa ilungelo elilodwa lomenzi wechiza ngo-1960 kwaye yaqala ukusetyenziswa kwezonyango ngo-1968. Ikuluhlu lwe-World Health Organisation of Essential Medicines, oludwelisa awona mayeza akhuselekileyo nasebenzayo afunekayo kwinkqubo yezempilo.Iyafumaneka njengamayeza enziwe afana nalawo aveliswe ngabenzi kwaye ayibizi.
7. I-N-Acetyl-L-Cysteine yindlela ye-acetylated ye-L-cysteine eye yaxutywa ngokufanelekileyo kwaye isetyenziswe.Ikwayi-antioxidant eluncedo kwiintsholongwane.I-N-Acetyl-l-Cysteine isetyenziswe njengesikhuseli sesibindi kunye nokwaphula i-pulmonary ne-bronchial mucus.
8. I-N-Acetyl-L-Cysteine inokunyusa amanqanaba e-glutathione kwiiseli.
9. I-N-Acetyl-L-Cysteine yi-amino acid eyimfuneko ngokwemeko, enye kuphela kwezintathu ezine-amino acid ezinesulfure, ezinye ziyi-taurine (enokuveliswa kwi-L-cysteine) kunye ne-L-methionine apho i-L-cysteine inokwazi. uveliswa emzimbeni ngenkqubo enamanyathelo amaninzi.
10. I-N-Acetyl-L-Cysteine inokusebenza njenge-antioxidant, inokuthintela izifo zesibindi, kwaye inokunceda ukuqinisa i-diameter nganye yeenwele ezikhoyo ukuba zithathwa rhoqo.
11. Ukusetyenziswa kwiinkalo zonyango Njenge-ejenti ye-Respiratory system, inokusetyenziswa njengeyeza lokunyibilikisa i-phlegm drums.inokunyanga ibronchitis.ngaphezu koko, i-N-Acetyl-L-Cysteine ingasetyenziswa njenge-antidote xa i-acetaminophen ityhefu.
12. Ukusetyenziswa kwiinkalo zokuthambisa i-N-Acetyl-L-Cysteine inempembelelo enkulu ekucoceni i-oxygen free radicals kunye nezinye i-oxides kunye nokucotha inkqubo yokuguga, kunokuphazamisa imveliso ye-melanin, kwaye iluncedo ekupheliseni i-freckle esikhumbeni.
13. Ukufakwa kwisondlo sezilwanyana i-N-Acetyl-L-Cysteine ingasetyenziswa njengesongezo sokutya.
14. Izithambiso ezisetyenziselwa ubuhle bamanzi, ulwelo lweperm, ikhrimu yokhathalelo lwelanga.Inomsebenzi wokuthintela ukuguga kwebhayoloji.I-N-Acetyl-l-Cysteine inokuthintela ngokufanelekileyo kunye nokunyanga ukulimala kwemitha.I-N-acetyl Cysteine inokususa i-melanin yesikhumba ngokwayo, itshintshe indalo yolusu ngokwayo, ulusu luba mhlophe ngokwendalo.
15. Ukongezwa kokutya.Isetyenziswe kwisonka, ukukhuthaza ukubunjwa kwegluten kunye nokukhuthaza ukuvutshelwa, ukubumba, ukuthintela ukuguga.Isetyenziswe kwiijusi zendalo ukukhusela i-vitamin C kwi-oxidizing kunye nokukhusela iijusi ukuba zitshintshe.
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