N-Acetyl-L-Tyrosine CAS 537-55-3 (Ac-Tyr-OH; NALT) Uvavanyo 99.0~101.0 Factory
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (i-CAS: 537-55-3) enomgangatho ophezulu.I-Ruifu Chemical ibonelela ngothotho lwee-amino acids kunye nezinto eziphuma kuzo.Imveliso ekumgangatho ophezulu, ixabiso elifanelekileyo, inkonzo ebalaseleyo kunye nekhawulezayo emva kokuthengisa zizibophelelo zeRuifu Chemical kubathengi.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kwi-N-Acetyl-L-Tyrosine,Please contact: alvin@ruifuchem.com
| Igama leMchiza | N-Acetyl-L-Tyrosine |
| Izithethantonye | Ac-Tyr-OH;Ac-L-Tyr-OH;N-Ac-L-Tyr;I-NALT;Ac-Tyrosine;iAcetyltyrosine;N-Acetyltyrosine;iAcetyl-Laevo-Tyrosine;I-LN-Acetyltyrosine;(2S)-2-(Acetylamino)-3-(4-Hydroxyphenyl)Propanoate;(S) -2-Acetamido-3-(4-Hydroxyphenyl)propanoic Acid;I-N-Acetyl-(S)-2-Amino-3-(4-Hydroxyphenyl)propionic Acid;(2S)-2-(Acetylamino)-3-(4-Hydroxyphenyl)propanoic Acid |
| Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso iiToni ezingama-30 ngonyaka |
| Inombolo yeCAS | 537-55-3 |
| Ifomula yeemolekyuli | C11H13NO4 |
| Ubunzima beMolekyuli | 223.23 g/mol |
| Indawo yokunyibilika | 150.0 ukuba 154.0℃ |
| Ukuxinana | 1.304 |
| Ukunyibilika kwamanzi | Inyibilika Emanzini, Phantse Ukungafihli |
| Ugcino Temp. | Itywinwe kwindawo eyomileyo, iVenkile kwindawo yobushushu beGumbi |
| I-COA kunye ne-MSDS | Iyafumaneka |
| Ukuhlelwa | Amino Acids & Derivatives |
| Uphawu | Ruifu Chemical |
| Iikhowudi zeNgozi | Xi - Uyacaphukisa | F | 10 |
| Iingxelo zoMngcipheko | 41-36/37/38 | I-TSCA | Ewe |
| Iingxelo zoKhuseleko | 26-39-36 | Ikhowudi ye-HS | 2922491990 |
| WGK eJamani | 3 |
| Izinto | ImiGangatho yokuHlola | Iziphumo |
| Imbonakalo | Iikristale eziMhlophe okanye umgubo weCrystalline | Iyahambelana |
| Ukuchongwa | I-Infrared Absorption Spectrum | Iyahambelana |
| Ukujikeleziswa okuthe ngqo [α]20/D | +46.5° ukuya +49.0°(C=2 kwi-H2O) | + 47,2 ° |
| Imeko yesisombululo (iTransmittance) | ≥96.0% | 98.3% |
| Ikloridi (Cl) | ≤0.020% | <0.020% |
| Isulfate (SO4) | ≤0.020% | <0.020% |
| I-Ammonium (NH4) | ≤0.020% | <0.020% |
| Intsimbi (Fe) | ≤30ppm | <30ppm |
| Iintsimbi ezinzima (Pb) | ≤10ppm | <10ppm |
| IArsenic (As2O3) | ≤2.0ppm | <2.0ppm |
| Tyrosine | ≤1.00% | Iyahambelana |
| Ilahleko ekomisweni | ≤0.50% | 0.25% |
| Intsalela ekutshisweni (iSulfated) | ≤0.10% | 0.07% |
| Isivavanyi | 99.0 ukuya kwi-101.0% | 99.5% |
| Ixabiso le-pH | 2.0 ukuya ku-3.0 | 2.3 |
| Ukuqukumbela | Idibana noMgangatho we-AJI97, USP35 | |
| Usetyenziso oluphambili | Izongezo zokutya;Izongezo zokutya;AbaPhakathi bamayeza | |
N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) AJI97 Indlela yoVavanyo
I-N-Acetyl-L-Tyrosine, xa yomisiwe, iqulethe ngaphantsi kweepesenti ze-99.0 kwaye ingabi ngaphezu kweepesenti ze-101.0 ze-N-Acetyl-L-Tyrosine (C11H13NO4).
inkcazelo: Iikristale ezimhlophe okanye umgubo crystalline, incasa kakhulu acid
Inyibilika ngokukhululekileyo emanzini.
Ukunyibilika (H2O, g/100g): 17.5 (20℃), 72.4 (40℃), 158 (60℃)
Ukuchonga: Thelekisa i-spectrum ye-infrared yokufunxa yesampuli kunye neyomgangatho we-potassium bromide disc method.
Ukujikeleza okuthe ngqo [α] 20 / D: Isampulu eyomileyo, C = 4, H2O
Imeko yeSolution (Transmittance): 0.5g kwi-10ml ye-H2O, i-spectrophotometer, i-430nm, i-10mm ubukhulu beeseli.
I-Chloride (Cl): 0.7g, A-1, ref: 0.40ml ye-0.01mol/L HCl
I-Ammonium (NH4): B-1
I-Sulfate (SO4): 1.2g, (1), i-ref: 0.50ml ye-0.005mol/L H2SO4
Intsimbi (Fe): 0.5g, ref: 1.5ml ye-Iron Std.(0.01mg/ml)
Iintsimbi ezinzima (Pb): 2.0g, (3), ref: 2.0ml yePb Std.(0.01mg/ml)
Arsenic (As2O3): 1.0g, (1), ref: 2.0ml ye-As2O3 Std.
Ilahleko ekomisweni: kwi-105℃ kwiiyure ezi-3
Intsalela kwi-Ignition (Sulfated): Uvavanyo lwe-AJI 13
Uvavanyo: Isampulu eyomileyo, 300mg, (1), 40ml H2O, (2), 0.1mol/L NaOH, 1ml=22.323mg C11H13NO4
Tyrosine: Ulwelo lwechromatography.Imeko yokusebenza: Umtshina: I-UV yokufunxa ifotometer (214nm);Ikholamu: ODS, 4.6mm x 150mm;Ubushushu beKholamu: Ubushushu begumbi.Izinga lokuhamba: 1ml / min;Isigaba seselula: isisombululo se-0.04mol / L se-monopotassium phosphate (pH 4.35): i-Methanol (193: 3)
pH: 1.25g kwi-50ml ye-H2O
Umda kunye nemeko yogcino ecetyiswayo: Izikhongozeli ezigciniweyo eziqinileyo kwiqondo lobushushu elilawulwayo kwigumbi (iminyaka emi-2).
I-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) Indlela yoVavanyo ye-USP35
INGCACISO
I-N-Acetyltyrosine iqulethe i-NLT 98.5% kunye ne-NMT 101.0% ye-C11H13NO4, njenge-N-Acetyl-L-Tyrosine, ibalwe ngokomisiweyo.
UKUCHAZA
A. UKUFUTSHWA KWE-IFRARED <197K>
B. UKUJONGANA KOMBONISO, Ukujikeleza okuthe ngqo <781S>
Isisombululo sesampuli: 10 mg / mL
Iinqobo zokwamkela: NLT +46.0 ° kunye ne-NMT +49.0 °, igqitywe kuma-20 °
C. Ixabiso le-RF lendawo ephambili yesisombululo seSampuli kuvavanyo lwe-Organic Impurities ihambelana nesisombululo soMgangatho woku-1.
UVAVANYO
INKQUBO
Isisombululo sesampuli: Dibanisa malunga ne-180 mg ye-N-Acetyltyrosine, ilinganiswe, kwi-50 mL yamanzi angenayo i-carbon dioxide.
Inkqubo yeTitrimetric
(Jonga i-Titrimetry <541>)
Imowudi: Ukubhalwa ngokuthe ngqo
I-Titrant: 0.1 N i-sodium hydroxide VS
Ukubonwa kwendawo yokugqibela: I-Potentiometric
Ukulingana: I-mL nganye ye-0.1 N i-sodium hydroxide VS ilingana ne-22.32 mg ye-C11H13NO4.
UBUNGCOLA
Ukungcola Kwezinto Eziphilayo
OKUSHIYELWE OKUSHIYELWE <281>: NMT 0.1%
I-CHLORIDE NE-SULFATE, I-Chloride <221> NMT 200 ppm.Ingxenye ye-0.7-g ayibonisi i-chloride ngaphezu kokuhambelana ne-0.40 mL ye-0.01 N i-hydrochloric acid.
I-CHLORIDE NE-SULFATE, i-Sulfate <221> NMT 200 ppm.Ingxenye ye-1.2-g ibonisa ukuba akukho sulfate ngaphezu kokuhambelana ne-0.25 mL ye-0.020 N sulfuric acid.
I-IRON <241>: NMT 20ppm
IIMETALI EZINZIMA, Indlela I <231>: NMT 10ppm
Ukungcola Okuphilayo
INKQUBO
I-Adsorbent: 0.25-mm umaleko we-chromatographic umxube we-silica gel
Isisombululo sesitokhwe esisemgangathweni 1: 8 mg / mL ye-USP N-Acetyl-L-tyrosine RS kumxube wamanzi, i-glacial acetic acid, kunye notywala (3: 3:94)
Isisombululo esisemgangathweni 1: Dilute Standard stock solution 1 ngotywala ukufumana isisombululo esinoxinzelelo olwaziwayo malunga ne-0.4 mg/mL
Isisombululo esiqhelekileyo sesi-2: 0.8 mg/mL ye-USP L-Tyrosine RS inyibilikiswe kumxube weglacial acetic acid kunye namanzi (1:1), kwaye ixutywe ngotywala
Isisombululo sesampuli: Dlulisa i-0.8 g ye-N-Acetyltyrosine kwi-flask ye-volumetric ye-10-mL, udibanise kwi-6 mL yomxube we-glacial acetic acid kunye namanzi (1: 1), kwaye uhlambulule ngotywala kwivolumu.
Umthamo wosetyenziso: 5 µL
Ukuphuhlisa inkqubo ye-solvent: Umxube we-ammonia kunye ne-2-propanol (3: 7)
I-reagent yokutshiza: Chitha i-0.2 g ye-ninhydrin kwi-100 mL yomxube we-butanol kunye ne-2 N acetic acid (95: 5).
Ukufaneleka kwenkqubo
Iimfuno zokufaneleka: Ichromatogram yesisombululo sokufaneleka kweSistim ibonisa amabala amabini ahluke ngokucacileyo.
Uhlalutyo: Qhuba njengoko kuchaziwe kwiChromatography <621> Thin-Layer Chromatography.Emva kokumisa ipleyiti emoyeni, phinda inkqubo yophuhliso.Emva kokumisa umoya okwesibini, fafaza nge-Spray reagent, kunye nobushushu phakathi kwe-100 ° kunye ne-105 ° malunga ne-15 min.
Iikhrayitheriya zokumkela: Nayiphi na indawo yesibini yesisombululo seSampuli ayinkulu okanye igxininise ngakumbi kuneyona ndawo inqununu yesisombululo soMgangatho we-1, ngaphandle kwendawo ehambelana ne-tyrosine, engekho enkulu okanye inamandla ngaphezu kwendawo eyintloko ukusuka kwisisombululo soMgangatho we-2.
Ukungcola komntu ngamnye: NMT 0.5%
Umda wetyrosine: NMT 1.0%
IIMVAVANYO EZITHILE
I-LASSON YOKOMA <731>: Yomisa isampulu kwi-105℃ kangange-3 h: ilahlekelwa yi-NMT nge-0.1% yobunzima bayo.
IIMFUNO EZONGEZELELWEYO
UKUPAKISHWA NOKUGCINA: Zigcine kwizikhongozeli ezivalwe kakuhle, uze uzigcine kwindawo yobushushu obulawulwayo begumbi.
IMIGANGATHO YE-USP REFERENCE <11>
USP N-Acetyl-L-tyrosine RS
USP L-Tyrosine RS
Iphakheji: Ibhotile eFluorinated, iAluminium foil bag, 25kg/Cardboard Drum, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo yokugcina impahla epholileyo, eyomileyo nengena umoya kude nezinto ezingahambelaniyo.Khusela ukukhanya kunye nokufuma.Gcina kude kwii-agent ezixutywayo ezinamandla.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Umsebenzi kunye nesicelo se-N-Acetyl-L-Tyrosine (Ac-Tyr-OH; NALT) (CAS: 537-55-3) powder
1. I-N-Acetyl-L-Tyrosine i-acetyl derivative ye-amino acid, i-L-tyrosine.Inyibilika ngokukhululekileyo emanzini xa kuthelekiswa ne-L-tyrosine kwaye isetyenziswa ngokuqhelekileyo njengesongezelelo sesondlo sabazali.I-N-Acetyl-L-Tyrosine, ifom ezinzileyo kunye ne-soluble ngakumbi ye-tyrosine, ifakwe kwezinye iifom ezikhoyo ngoku zentengiso ye-parenteral amino acid ezifana ne-TrophAmine kunye ne-Aminosyn-II.
2. I-N-Acetyl-L-Tyrosine ibandakanyeka kwimveliso ye-catecholamine.Ingasetyenziswa njengecandelo lemidiya yenkcubeko yeseli kwintengiso ye-biomanufacture ye-recombinant proteins zonyango kunye ne-monoclonal antibodies.
3. I-N-Acetyl-L-Tyrosine yinto ebalulekileyo ye-amino acids, eluhlobo lwesondlo esibalulekileyo kwi-metabolism yabantu kunye nezilwanyana, ukukhula kunye nophuhliso ludlala indima ebalulekileyo, lunokusetyenziswa ngokubanzi ekutyeni, kumayeza njl.
4. I-N-Acetyl-L-Tyrosine idlala indima efunekayo kwi-synthesis ye-dopamine kunye namanye amahomoni emzimbeni wakho.Inokunyusa amanqanaba e-neurotransmitters i-dopamine, i-norepinephrine kunye ne-epinephrine.Inceda ukuxhasa amanqanaba aphezulu okugxila kunye nokusebenza kwengqondo.Inokunyusa inkumbulo yokusebenza kunye neemvakalelo zokuba sempilweni.
5. I-N-Acetyl-L-Tyrosine iguqulwa ukusuka kwiTyrosine eqhelekileyo kuba iqulethe ukongezwa kwe-acetic acid.Oku kunceda ukunyusa i-bioavailability yekhompawundi ukuze ifunxeke ngokuthe ngqo kwigazi.
6. I-N-Acetyl-L-Tyrosine yindlela ephezulu ye-bioavailable ye-L-Tyrosine yonyango lwe-precursor yendalo ye-moods ephantsi i-N-Acetyl-L-Tyrosine ingasetyenziselwa kwiidosi eziphantsi kune-L-Tyrosine.I-L-Tyrosine eqhelekileyo ayizinzile kwaye ayinyibiliki emanzini, nto leyo enokubangela ukunciphisa i-bioavailability.
7. I-N-Acetyl-L-Tyrosine iphucula ukunyibilika kunye nokuzinza okwenza kube yifom efunyenwe ngokukhawuleza kunye ne-bioavailable ye-amino acid L-Tyrosine engaphantsi kwe-urinary excretion.
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