Naproxen CAS 22204-53-1 Ubunyulu > 99.5% (HPLC)
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi weNaproxen (i-CAS: 22204-53-1) enomgangatho ophezulu.Sinokubonelela nge-COA, ukuhanjiswa kwehlabathi jikelele, ubuninzi obuncinci kunye nobuninzi obukhoyo.Ukuba unomdla kule mveliso, nceda uthumele ulwazi oluneenkcukacha lubandakanya inombolo ye-CAS, igama lemveliso, ubuninzi kuthi.Please contact: alvin@ruifuchem.com
Igama leMchiza | (S)-(+)-2-(6-Methoxy-2-Naphthyl)propionic Acid |
Izithethantonye | iNaproxen;(S)-Naproxen;(S)-(+)-Naproxene;(S)-(+)-6-Methoxy-α-Methyl-2-Naphthaleneacetic Acid;(+)-6-Methoxy-alpha-Methyl-2-Naphthaleneacetic Acid |
Inombolo yeCAS | 22204-53-1 |
Inombolo yeCAT | RF2890 |
Ubume beStokhwe | KwiSitokhwe, Umthamo weMveliso ye-1000 yeeToni ngonyaka |
Ifomula yeemolekyuli | C14H14O3 |
Ubunzima beMolekyuli | 230.26 |
Indawo yokunyibilika | 154.0 ~ 158.0℃ |
Ugcino & Novakalelo | Ukukhanya okunovelwano.Ubushushu be-Ambient |
Ukunyibilika | Ayinyibiliki ngokupheleleyo emanzini.Inyibilika kwi-Ethanol (96%) nakwiMethanol |
IKlasi yeeNgozi | 6.1(b) |
Iqela lokuPakisha | III |
Ikhowudi ye-HS | 29189900 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kuMhlophe oMhlophe wePowder |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Ubunyulu / Indlela yokuHlalutya | >99.0% (iNeutralization Titration) |
Indawo yokunyibilika | 154.0 ~ 158.0℃ |
Ukujikeleziswa okuthe ngqo [α]20/D | +83.0 ° ukuya +89.5 ° |
Ilahleko ekomisweni | <0.50% |
Intsalela kwi-Ignition | <0.20% |
Iintsimbi ezinzima | <0.002% |
Izinto ezinxulumeneyo | |
Ukungacoceki Okukodwa | <0.50% |
Ukungcola ngokupheleleyo | <1.00% |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-Active Pharmaceutical Ingredients (API) kunye ne-Intermediates |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo.Khusela ukukhanya kunye nokufuma.Ayihambelani ne-oxidizing agents ezinamandla.
Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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I-Naproxen (i-CAS: i-22204-53-1) iyiyobisi engeyiyo i-steroidal anti-inflammatory, yi-PG synthase inhibitor, enokuthintela i-prostaglandin synthetase, ineempembelelo ezibalulekileyo ze-analgesic kunye ne-antipyretic, ukufunxa ngomlomo ngokukhawuleza kwaye kuphelile, i-2 ukuya. Kwiiyure ezi-4 emva kwedosi, ugxininiso lwe-plasma lufikelela kwincopho, egazini, ngaphezu kwe-99% ibophelelwe kwiiprotheni ze-plasma, i-t1/2 yi-13 kwiiyure ze-14, malunga ne-95% ikhutshwe kumchamo kunye neprototype kunye ne-metabolites.Isetyenziselwa unyango lwe-rheumatic kunye ne-rheumatoid arthritis, i-osteoarthritis, i-ankylosing spondylitis, i-gout, isifo samathambo, i-tenosynovitis.Kodwa kufuneka kuqatshelwe ukuba njengamanye amachiza achasene nokudumba kwe-non-steroidal, iingxaki ezifanayo zesisu zinokwenzeka nangaliphi na ixesha ngelixa uthatha i-naproxen ngexesha lonyango, ngoko ke izigulana ezisebenzayo ze-gastroduodenal ulcer ziyaxhonywa, ezinye izigulana zesifo sesisu kufuneka zithathe oku. iyeza eliphantsi kweliso likagqirha.I-Naproxen yenziwe kwi-2-methoxynaphthalene kunye ne-(+)-isomer efunyenwe ngesisombululo kunye ne-cinchonidine (61).Yaziswa e-United States ngo-1976 kwaye, njengechiza elenziwe lafana nalawo aveliswe ngabenzi, ibisoloko iphakathi kwee-NSAID ezaziwa kakhulu.Ithengiswa njenge-S-(+)-enantiomer, kodwa umdla, ityuwa yesodium ye (-) -isomer ikwakwimarike njenge Anaprox.Njenge-inhibitor ye-prostaglandin biosynthesis, inamandla aphindwe ka-12 kune-aspirin, amaxesha angama-10 ngaphezu kwe-phenylbutazone, kathathu ukuya kwamane anamandla kune-ibuprofen, kwaye aphindwe kane ngaphezu kwe-fenoprofen, kodwa malunga namaxesha angama-300 angaphantsi kwamandla indomethacin.