Olmesartan Medoxomil CAS 144689-63-4 Ubunyulu > 99.5% (HPLC) API Factory

Inkcazelo emfutshane:

Igama leMichiza: Olmesartan Medoxomil

I-CAS: 144689-63-4

Ubunyulu: >99.5% (HPLC)

Imbonakalo: Mhlophe ukuya phantse eMhlophe Cyrstalline Powder

I-Angiotensin II Receptor Antagonist.I-Anti-Hypertensive

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Olmesartan Medoxomil Intermediate with High Quality:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
I-4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
I-Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
I-Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
I-Trityl Olmesartan Acid CAS 761404-85-7
I-N2-Trityl Olmesartan Acid CAS 752179-89-8
I-Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4

Iipropati zeMichiza:

Igama leMchiza	Olmesartan Medoxomil
Izithethantonye	4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Ester;CS-866
Inombolo yeCAS	144689-63-4
Inombolo yeCAT	RF-PI1730
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C29H30N6O6
Ubunzima beMolekyuli	558.60
Indawo yokunyibilika	180℃ (ngoDisemba)
Ukunyibilika kwamanzi	Ukunganyibiliki emanzini;Inyibilika kancinane kwi-DMSO
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	I-White Cyrstalline Powder ephantse imhlophe
Ukuchongwa	I-IR, i-HPLC, i-UV: Kufuneka ihambelane neMigangatho yoReferensi
Ubunyulu / Indlela yokuHlalutya	>99.5% (HPLC kwi-Anhydrous and Solvent-Free Basics)
Ilahleko ekomisweni	<0.50%
Intsalela kwi-Ignition	<0.10%
Izinto ezinxulumeneyo
I-Olmesartan RRT 0.2	<0.50%
Olmesartan Medoxoil Related Compound A. RRT 0.7	<0.20%
Ukungacoceki kwe-Olefinic RRT 1.6	<0.50%
N-Alkyl Ukungcola RRT 3.4	<0.10%
Nakuphi na Okunye Ukungcola	<0.10%
Ukungcola ngokupheleleyo	<0.50%
Iintsimbi ezinzima (njenge Pb)	<10ppm
pH yesisombululo (2%, W/V)	4.5 ukuya ku-6.5
Umgangatho woVavanyo	uMgangatho woShishino;Umgangatho we-USP
Ukusetyenziswa	API

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Olmesartan Medoxomil (CS-866) (i-CAS: 144689-63-4) i-angiotensin II enamandla kwaye ikhetha uhlobo lwe-1 (AT (1)) i-receptor antagonist kunye ne-IC50 ye-66.2 μM., esetyenziswa kunyango lwegazi eliphezulu.Isetyenziswa njenge-anti-hypertensive.I-Olmesartan isebenza ngokuthintela ukubophelela kwe-angiotensin II kwi-AT1 receptors kwi-vascular muscle.Ngokuthintela ukubopha endaweni yokwenziwa kwe-angiotensin II, i-Olmesartan inqanda ingxelo engalunganga yolawulo kwi-renin secretion.I-Olmesartan i-Medoxomil liyeza elisetyenziswayo eliye lakhutshwa kwi-metabolite esebenzayo, i-olmesartan.I-Olmesartan Medoxomil yasungulwa e-US njenge-Benicar, unyango olulawulwa ngomlomo loxinzelelo lwegazi.