I-Omeprazole Sulfide CAS 73590-85-9 Ucoceko > 99.0% (HPLC) Factory

Inkcazelo emfutshane:

Igama leKhemikhali: Omeprazole Sulfidi

Izithethantonye: Ufiprazole

CAS: 73590-85-9

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Imhlophe ukuya kwiPowder eNgaphandle-Mhlophe okanye iiCrystals

Umgangatho ophezulu, iMveliso yoRhwebo

Phakathi kweOmeprazole / Esomeprazole

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza Omeprazole Sulfide
Izithethantonye Ufiprazole;iOmeprazole Sulfur Etere;Esomeprazol EP Ukungcola C;I-Omeprazole EP Ukungcola C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl]thio]benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole
Inombolo yeCAS 73590-85-9
Inombolo yeCAT RF-PI1914
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C17H19N3O2S
Ubunzima beMolekyuli 329.42
Indawo yokunyibilika 122.0 ukuba 126.0℃
Ukunyibilika Inyibilika kwiMethanol
Ukuxinana 1.28±0.10 g/cm3
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Mhlophe ukuya kwiPowder eNgaphandle-Mhlophe okanye iiCrystals
Ubunyulu / Indlela yokuHlalutya >99.0% (HPLC)
Ilahleko ekomisweni <1.00%
Intsalela kwi-Ignition <0.20%
Iintsimbi ezinzima (njenge Pb) <20ppm
Ukungacoceki Okukodwa <0.50%
Ukungcola ngokupheleleyo <1.00%
I-Infrared Spectrum Iyahambelana noLwakhiwo
Proton NMR Spectrum Iyahambelana noLwakhiwo
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Phakathi kweOmeprazole / Esomeprazole

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-Omeprazole Sulfide (i-CAS: 73590-85-9) yindawo ephakathi esetyenziselwa ukuveliswa kwe-gastric proton pump inhibitors, i-Omeprazole (CAS: 73590-58-6) kunye ne-Esomeprazole (CAS: 119141-88-7), i-Esomeprazole Sodium ( I-CAS: 161796-78-7).Njengemveliso yokuthotywa, kubikwa ukuba yi-inhibitor esebenza ngokuthe ngqo ye-cytochrome P450 2C19 kwi-microsomes yesibindi somntu (IC50 = 9.7 μM).I-Omeprazole Sulfide yi-metabolite ye-Omeprazole.I-Esomeprazole Sodium luhlobo lwetyuwa yesodium ye-esomeprazole.Lichiza elisetyenziswa ngokuqhelekileyo lokulwa nezilonda, elaqala ukuphuhliswa ngempumelelo yinkampani yaseSweden i-Astra Zeneca kuqala.Yeyeproton pump inhibitor.Iproton pump inhibitor lolona khetho luphambili lokunyanga isilonda se-peptic, isifo se-gastro-oesophageal reflux kunye nezinye izifo ezinxulumene ne-asidi.Okwangoku iPPI esetyenziswa ngokuqhelekileyo ekliniki iquka iindidi ezintlanu: iOmeprazole, iLansoprazole, iRabeprazole, iPantoprazole kunye neEsomeprazole.NjengePPI yokuqala, ukusebenza kwechiza le-omeprazole ekunyangeni izifo ezinxulumene ne-asidi kuye kwaqatshelwa ngokubanzi.I-Esomeprazole yi-S-isomer ye-Omeprazole, enokunciphisa ukukhutshwa kwe-asidi yesisu ngendlela ethile yokujolisa.Yi-inhibitor ethile ye-proton pump inhibitor kwi-parietal cell.Ngenxa yenzuzo yemetabolism ye-esomeprazole, inobukho obuphezulu be-bioavailability kunye ne-pharmacokinetics engaguqukiyo kuneqabane layo, i-Omeprazole Sodium, inyusa ichiza elifikelela kwimpompo yeproton.Indima yayo yokulawula i-asidi yesisu ingcono kakhulu kunezinye iiproton pumps inhibitors ezifana neLansoprazole, iPantoprazole, kunye neRabeprazole.

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