I-Omeprazole Sulfide CAS 73590-85-9 Ucoceko > 99.0% (HPLC) Factory
IRuifu Chemical Supply Omeprazole Intermediate with High Purity
Omeprazole CAS 73590-58-6
I-Omeprazole Hydroxy Compound CAS 86604-78-6
I-Omeprazole Chloride Compound CAS 86604-75-3
Omeprazole Sulfide CAS 73590-85-9
2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1
I-2-Cyano-3-Methylpyridine CAS 20970-75-6
2,3,5-Trimethylpyridine CAS 695-98-7
Igama leMchiza | Omeprazole Sulfide |
Izithethantonye | Ufiprazole;iOmeprazole Sulfur Etere;Esomeprazol EP Ukungcola C;I-Omeprazole EP Ukungcola C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl]thio]benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole |
Inombolo yeCAS | 73590-85-9 |
Inombolo yeCAT | RF-PI1914 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C17H19N3O2S |
Ubunzima beMolekyuli | 329.42 |
Indawo yokunyibilika | 122.0 ukuba 126.0℃ |
Ukunyibilika | Inyibilika kwiMethanol |
Ukuxinana | 1.28±0.10 g/cm3 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kwiPowder eNgaphandle-Mhlophe okanye iiCrystals |
Ubunyulu / Indlela yokuHlalutya | >99.0% (HPLC) |
Ilahleko ekomisweni | <1.00% |
Intsalela kwi-Ignition | <0.20% |
Iintsimbi ezinzima (njenge Pb) | <20ppm |
Ukungacoceki Okukodwa | <0.50% |
Ukungcola ngokupheleleyo | <1.00% |
I-Infrared Spectrum | Iyahambelana noLwakhiwo |
Proton NMR Spectrum | Iyahambelana noLwakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kweOmeprazole / Esomeprazole |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-Omeprazole Sulfide (i-CAS: 73590-85-9) yindawo ephakathi esetyenziselwa ukuveliswa kwe-gastric proton pump inhibitors, i-Omeprazole (CAS: 73590-58-6) kunye ne-Esomeprazole (CAS: 119141-88-7), i-Esomeprazole Sodium ( I-CAS: 161796-78-7).Njengemveliso yokuthotywa, kubikwa ukuba yi-inhibitor esebenza ngokuthe ngqo ye-cytochrome P450 2C19 kwi-microsomes yesibindi somntu (IC50 = 9.7 μM).I-Omeprazole Sulfide yi-metabolite ye-Omeprazole.I-Esomeprazole Sodium luhlobo lwetyuwa yesodium ye-esomeprazole.Lichiza elisetyenziswa ngokuqhelekileyo lokulwa nezilonda, elaqala ukuphuhliswa ngempumelelo yinkampani yaseSweden i-Astra Zeneca kuqala.Yeyeproton pump inhibitor.Iproton pump inhibitor lolona khetho luphambili lokunyanga isilonda se-peptic, isifo se-gastro-oesophageal reflux kunye nezinye izifo ezinxulumene ne-asidi.Okwangoku iPPI esetyenziswa ngokuqhelekileyo ekliniki iquka iindidi ezintlanu: iOmeprazole, iLansoprazole, iRabeprazole, iPantoprazole kunye neEsomeprazole.NjengePPI yokuqala, ukusebenza kwechiza le-omeprazole ekunyangeni izifo ezinxulumene ne-asidi kuye kwaqatshelwa ngokubanzi.I-Esomeprazole yi-S-isomer ye-Omeprazole, enokunciphisa ukukhutshwa kwe-asidi yesisu ngendlela ethile yokujolisa.Yi-inhibitor ethile ye-proton pump inhibitor kwi-parietal cell.Ngenxa yenzuzo yemetabolism ye-esomeprazole, inobukho obuphezulu be-bioavailability kunye ne-pharmacokinetics engaguqukiyo kuneqabane layo, i-Omeprazole Sodium, inyusa ichiza elifikelela kwimpompo yeproton.Indima yayo yokulawula i-asidi yesisu ingcono kakhulu kunezinye iiproton pumps inhibitors ezifana neLansoprazole, iPantoprazole, kunye neRabeprazole.