Palbociclib CAS 571190-30-2 Ubunyulu > 99.5% (HPLC) API Factory

Inkcazelo emfutshane:

Igama leKhemikhali: Palbociclib

CAS: 571190-30-2

Ubunyulu: >99.5% (HPLC)

Imbonakalo: I-White okanye i-Off-White Powder

I-API kuNyango loMhlaza wamabele

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
I-5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7 (8H)-enye CAS 1016636-76-2
I-2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-enye CAS 1013916-37-4

Iipropati zeMichiza:

Igama leMchiza	Palbociclib
Izithethantonye	PD-0332991;Otava-Bb 1115529;Ibrance
Inombolo yeCAS	571190-30-2
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C24H29N7O2
Ubunzima beMolekyuli	447.54
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe okanye oMhlophe
I-1H NMR Spectrum	Ukungqinelana Nolwakhiwo
HPLC	Ukungqinelana Nolwakhiwo
Izinto ezinxulumeneyo
Ukungacoceki komntu	<0.50%
Ukungcola ngokupheleleyo	<1.00%
Ilahleko ekomisweni	<0.50%
Intsalela kwi-Ignition	<0.10%
Iintsimbi ezinzima	<10ppm
Ubunyulu / Indlela yokuHlalutya	>99.5% (HPLC)
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	I-API, kuNyango loMhlaza wamabele

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Palbociclib (i-CAS: 571190-30-2) ifumaneka ngomlomo kwi-cyclin-dependent kinase (CDK) inhibitor ene-antineoplastic activity.I-Palbociclib inqanda ngokukhethekileyo i-cyclin-dependent kinase 4 (CDK4) kunye ne-6 (CDK6), ngaloo ndlela inqanda i-retinoblastoma (Rb) i-protein phosphorylation ekuqaleni kwesigaba se-G1 esikhokelela ekubanjweni komjikelo weseli.Oku kucinezela ukuphindaphinda kwe-DNA kwaye kunciphisa ukwanda kweeseli zethumba.IPalbociclib ngummeli wokuqala wodidi olutsha lwechiza lwe-cyclin-dependent kinase inhibitors.Esi siphumo sinciphisa ukwanda kweeseli (ukukhula kweeseli kunye nokwahlukana).Isetyenziswa njenge-arhente ye-antineoplastic kumhlaza webele ophezulu okanye we-metastatic.