Palbociclib Intermediate CAS 1016636-76-2 Ubunyulu > 99.0% (HPLC) Factory

Inkcazelo emfutshane:

Igama leMichiza: 6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-enye

CAS: 1016636-76-2

Ubunyulu: >99.0% (HPLC)

Imbonakalo: Umgubo oMhlophe ukuya kokuKhanyayo oMthubi

Umbindi wePalbociclib (CAS: 571190-30-2)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

I-Ruifu Chemical Supply Palbociclib Related Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
I-5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7 (8H)-enye CAS 1016636-76-2
I-2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-enye CAS 1013916-37-4

Iipropati zeMichiza:

Igama leMchiza	6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-enye
Izithethantonye	Palbociclib-Pb3
Inombolo yeCAS	1016636-76-2
Inombolo yeCAT	RF-PI1849
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	I-C13H13BrClN3O
Ubunzima beMolekyuli	342.63
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe ukuya koMthubi oKhanyayo
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC)
Izinto ezinxulumeneyo	<1.00%
Ilahleko ekomisweni	<0.50%
Amanzi (KF)	<0.50%
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi wePalbociclib (CAS: 571190-30-2)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7 (8H)-enye (CAS: 1016636-76-2) iphakathi kwePalbociclib (CAS: 571190- 30-2).I-Palbociclib lichiza lokunyanga i-ER-positive kunye ne-HER2-negative umhlaza webele ophuhlisiwe.I-Palbociclib yi-inhibitor ekhethiweyo ye-cyclin-dependent kinases CDK4 kunye ne-CDK6.Ngomhla we-3 kaFebruwari, i-2015, i-US FDA yavuma i-Pfizer's Palbociclib (igama lokuthengisa: Ibrance) kunyango lomhlaza webele ophezulu / we-metastatic kubasetyhini be-postmenopausal.IPalbociclib yi-CDK4/6 inhibitor yokuqala ukufumana imvume ye-FDA.