Perindopril Erbumine CAS 107133-36-8 Ubunyulu >99.5% (HPLC) ACE Inhibitor API Factory High Quality
Ubonelelo loMvelisi wePerindopril Erbumine eNxulumene neMidiya
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(S)-(-)-Indoline-2-Carboxylic Acid CAS 79815-20-6
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Perindopril Erbumine CAS 107133-36-8
Igama leMchiza | I-Perindopril Erbumine |
Izithethantonye | Ityuwa yePerindopril tert-Butylamine;I-aceon;(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine ityuwa |
Inombolo yeCAS | 107133-36-8 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C19H32N2O5.C4H11N |
Ubunzima beMolekyuli | 441.61 |
Indawo yokunyibilika | 126.0 ~ 128.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe okanye oMhlophe |
Ukuchongwa | I-IR;HPLC |
Ukujikeleziswa okuthe ngqo [α]D20 | -66.0 ° ~ -69.0 ° |
Ukungcola A | ≤0.25% |
Ukungcola I | ≤0.10% |
Ukungcola okungaziwayo | ≤0.10% |
Ukungcola E | ≤0.40% |
Ukungcola B | ≤0.30% |
Ukungcola F | ≤0.20% |
Ukungcola H | ≤0.20% |
Ukungcola okungaziwayo | ≤0.10% |
Ukungcola ngokupheleleyo | <0.50% |
Isiqulatho samanzi | ≤1.00% |
Intsalela kwi-Ignition | ≤0.10% |
Iintsimbi ezinzima | ≤20ppm |
Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) |
Izinto ezinxulumeneyo | Hlangana neNkcazo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API;I-ACE Inhibitor;I-Antihypertensive |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
I-Perindopril Erbumine (i-CAS: 107133-36-8), eyaziwa nangokuthi i-Perindopril tert-Butylamine Ityuwa, i-ACE inhibitor enamandla esetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu, ukungaphumeleli kwentliziyo okanye isifo se-coronary ezinzile.Ukuvinjelwa kwale enzyme kuthintela ukubunjwa kwe-angiotensin II kwi-angiotensin I, nto leyo ekhusela i-vasoconstriction ebangelwa yi-angiotensin II.I-Perindopril Erbumine yi-oral bioavailable long acting angiotensin converting enzyme (ACE) inhibitor (ixabiso le-IC50 le-10 μM).Ngokukodwa, iPerindopril Erbumine yimveliso yomlomo yePerindoprilat, i-ACE inhibitor enamandla enexabiso le-IC50 le-1.9 nM.