Paxlovid Boceprevir Intermediate CAS 565456-77-1 Assay ≥99.0%

Inkcazelo emfutshane:

Igama: (1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride

CAS: 565456-77-1

Imbonakalo: Mhlophe ukuya kwi-Off-White Powder

Uvavanyo: ≥99.0%

Phakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kunye ne-Boceprevir (CAS 394730-60-0)

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo PF-07321332 Paxlovid abaPhakathi abaNxungupheleyo abanoMgangatho oPhezulu
I-L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
I-Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
I-Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9

Iipropati zeMichiza:

Igama leMchiza	(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride
Izithethantonye	I-Methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate Hydrochloride
Inombolo yeCAS	565456-77-1
Inombolo yeCAT	RF-PI318
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C9H15NO2.ClH
Ubunzima beMolekyuli	205.683
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kwi-Off-White Powder
Isazisi A	I-IR: Ifana neNgcaciso yeNgcaciso
Isazisi B	Ixesha lokuGcina: Liyafana neNxibelelwano yeSiza
I-Enantiomer	≤0.15%
Ukungcola okunxulumeneyo (nge-HPLC)
Ukungacoceki okungaziwayo	≤0.20%
Ukungcola ngokupheleleyo	≤1.0%
Amanzi	≤0.50%
Intsalela kwi-Ignition	≤0.10%
Iintsimbi ezinzima	≤20ppm
Isivavanyi	≥99.0%
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Phakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kunye ne-Boceprevir (CAS 394730-60-0)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

(1R,2S,5S) -6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride (CAS 565456-77-1) i-azabicyclohexane derivative esetyenziselwa ukulungiswa kwe-hepatitis C. intsholongwane (HCV) NS3 serine protease inhibitor.Kuphakathi kwe-PF-07321332 Paxlovid (CAS 2628280-40-8) kunye ne-Boceprevir (CAS 394730-60-0).PF-07321332 inamandla kwaye iyasebenza ngomlomo i-SARS-CoV 3C-efana ne-protease (3CLPRO) inhibitor.PF-07321332 ekujoliswe kuyo kwintsholongwane ye-SARS-CoV-2 kwaye inokusetyenziselwa uphando lwe-COVID-19.I-Boceprevir (INN, igama lokurhweba i-Victrelis) yi-protease inhibitor esetyenziswa njengonyango lwe-hepatitis C genotype 1. Ibophelela kwi-HCV nonstructural 3 NS3 (HCV) indawo esebenzayo.Yayiphuhliswa yi-Schering-Plough, kodwa ngoku iphuhliswa yi-Merck ukususela ekubeni i-Schering yafunyanwa ngo-2009. Yavunywa yi-FDA ngoMeyi 13, 2011.