Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9 Posaconazole Umgangatho oPhakamileyo oPhakathi

Inkcazelo emfutshane:

Igama leMichiza: Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

CAS: 184177-81-9

Umbindi wePosaconazole (CAS 171228-49-2) Triazole Agent Antifungal

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com


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Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Izithethantonye I-Posaconazole ePhakathi
Inombolo yeCAS 184177-81-9
Inombolo yeCAT RF-PI290
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli I-C23H23N3O3
Ubunzima beMolekyuli 389.45
Ukuxinana 1.296
Imeko yokuthumela ngenqanawa Phantsi koBubushushu be-Ambient
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Umdaka omdaka ukuya kumgubo oMvu
Ubunyulu / Indlela yokuHlalutya ≥99.0% (HPLC)
Ilahleko ekomisweni ≤0.50%
Intsalela kwi-Ignition ≤0.20%
Iintsimbi ezinzima ≤20ppm
Ukungacoceki Okukodwa ≤0.50%
Ukungcola ngokupheleleyo ≤1.0%
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Umbindi wePosaconazole (CAS 171228-49-2)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-Phenyl (4- (4- (4-hydroxyphenyl) ipiperazin-1-yl) phenyl)carbamate (CAS 184177-81-9) yi-Intermediate ye-Posaconazole (CAS 171228-49-2).I-Posaconazole i-spectrum ebanzi, isizukulwana sesibini, i-triazole edibeneyo kunye nomsebenzi we-antifungal.Yavunywa ukuba isetyenziswe kwezonyango e-United States ngoSeptemba 2006, kwaye iyafumaneka njengeyeza elenziwe lafana nelo lomenzi wechiza.I-Posaconazole lichiza le-triazole le-antifungal elithengiswa e-United States ngu-Schering-Plough phantsi kwegama lezorhwebo elithi Noxafil.I-Posaconazole isebenza ngokuphazamisa ukupakishwa okusondeleyo kwama-acyl chain of phospholipids, ukuphazamisa imisebenzi yeenkqubo ezithile ze-enzyme eziboshwe kwi-membrane ezifana ne-ATPase kunye ne-enzymes yenkqubo yokuthutha i-electron, ngaloo ndlela inqanda ukukhula kwefungi.Ikwenza oku ngokuthintela ukuhlanganiswa kwe-ergosterol ngokuvimbela i-enzyme i-lanosterol 14a-demethylase kunye nokuqokelela i-methylated sterol precursors.

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