I-Posaconazole ePhakathi CAS 170985-85-0 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy) propyl]hydrazinecarboxaldehyde
IFactory Supply Posaconazole Related Intermediates, Commercial Production
I-Posaconazole CAS 171228-49-2
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2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
I-Diethyl L-(+)-Tartrate CAS 87-91-2
Igama leMchiza | 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde |
Izithethantonye | N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide;N-[[(2S,3S)-2-phenylmethoxypentan-3-yl]amino]formamide;I-Posaconazole ePhakathi;Ukungacoceki kwePosaconazole 33 |
Inombolo yeCAS | 170985-85-0 |
Inombolo yeCAT | RF-PI292 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C13H20N2O2 |
Ubunzima beMolekyuli | 236.31 |
Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe okanye oMhlophe |
Ukuchongwa | H-NMR: Ihambelana noMgangatho |
Ilahleko ekomisweni | ≤0.50% |
Ubunyulu / Indlela yokuHlalutya | ≥98.0% (HPLC) |
Ukungcola Okuphilayo | |
Nakuphi na Ukungacoceki Okukodwa | ≤0.50% |
Ubumdaka obupheleleyo bezinto eziphilayo | ≤2.0% |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Phakathi kwePosaconazole (CAS 171228-49-2) i-Agent ye-Antifungal |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-2 - [(1S,2S) -1-Ethyl-2- (Phenylmethoxy) propyl]hydrazinecarboxaldehyde (CAS: 170985-85-0) yinto ebalulekileyo ephakathi kwePosaconazole (CAS 171228-49-2).I-Posaconazole lichiza le-antifungal le-triazole elisetyenziswa ngokubanzi kunyango lwezifo ezihlaselayo.I-Posaconazole yi-wide-spectrum triazole compound esebenzayo ngokuchasene nefungi ngokuvimbela i-enzyme ye-lanosterol 14α-demethylase.I-Posaconazole ivela kwi-itraconazole.Iziphumo zayo ze-pharmacological zifana ne-azoles, kodwa xa kuthelekiswa ne-Itraconazole, inomphumela onamandla wokuthintela kwi-C14 demethylation ye-steroid, ngakumbi i-Aspergillus.I-Posaconazole, eyasungulwa e-UK, ilungu elitsha leklasi ye-azole ye-antifungal agents ukufikelela kwimarike.