I-Posaconazole ePhakathi ye-POA CAS 149809-43-8 Umgangatho ophezulu weFactory
IFactory Supply Posaconazole Related Intermediates, Commercial Production
I-Posaconazole CAS 171228-49-2
I-Posaconazole ePhakathi POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
I-Diethyl L-(+)-Tartrate CAS 87-91-2
Igama | I-Posaconazole ePhakathi POA |
Izithethantonye | (5R-cis) -Toluene-4-sulfonic acid 5- (2,4-difluorophenyl) -5- (1H-1,2,4-triazol-1-yl) methyltetrahydrofuran-3-ylmethyl ester;(3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl p-Toluenesulfonate |
Inombolo yeCAS | 149809-43-8 |
Inombolo yeCAT | RF-PI291 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | I-C21H21F2N3O4S |
Ubunzima beMolekyuli | 449.47 |
Ukuxinana | 1.40 |
Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe ukuya kuNgwevu |
Ukuchongwa | IR Ngokuhambelana nomgangatho |
Indawo yokunyibilika | 100.0-102.0℃ |
Ujikelezo oluKhethekileyo [a]20/D | -40.0 ° ukuya -48° (C=1, CHCl3) |
Ilahleko ekomisweni | ≤0.50% |
Intsalela kwi-Ignition | ≤0.20% |
Iintsimbi ezinzima | ≤20ppm |
Izinto ezinxulumeneyo | |
Ukungcola Okukhulu | ≤0.40% |
POA-Enantiomer | ≤0.10% |
I-POA-Diastereomer | ≤0.20% |
Ukungacoceki komntu Okungaziwayo | ≤0.20% |
Ukungcola ngokupheleleyo | ≤1.0% |
Ubunyulu | ≥99.0% |
Isivavanyi | 98.0%~102.0% (into engenamanzi) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi wePosaconazole (CAS 171228-49-2) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester (CAS 149809-43) -8) yi-Intermediate ye-Posaconazole (i-CAS 171228-49-2).I-Posaconazole i-agent ye-triazole ye-antifungal evimbela ukuhlanganiswa kwe-ergosterol ngokuvimbela i-enzyme lanosterol 14α-demethylase kunye nokuqokelela i-methylated sterol precursors, inamandla ngakumbi ekuvimbeleni i-14α-demethylase kune-itraconazole.