Pregabalin CAS 148553-50-8 Ubunyulu > 99.0% (HPLC) Antiepileptic API

Inkcazelo emfutshane:

Igama leKhemikhali: Pregabalin

CAS: 148553-50-8

Imbonakalo: Mhlophe ukuya kuMhlophe-Mhlophe wePowder

Ubunyulu: > 99.0% (HPLC ngokomisiweyo)

Iyeza lesibini lesibini le-Antiepileptic (AED)

Umgangatho ophezulu we-API, iMveliso yoRhwebo

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Umenzi onobunyulu obuPhezulu kunye neMveliso yoRhwebo
Igama leKhemikhali: PregabalinCAS: 148553-50-8
I-Pregabalin sisiyobisi se-antiepileptic sesizukulwana sesibini (AED)

Iipropati zeMichiza:

Igama leMchiza	Pregabalin
Izithethantonye	(S) -3-(Aminomethyl) -5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;I-CI-1008;Lyrica
Inombolo yeCAS	148553-50-8
Inombolo yeCAT	RF-API57
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C8H17NO2
Ubunzima beMolekyuli	159.23
Indawo yokunyibilika	194.0 ~ 196.0℃
Ukunyibilika emanzini	Ayinyibiliki ngokupheleleyo emanzini
Ukunyibilika	Kancinci kakhulu ukunyibilika kwi-Ethanol
Imeko yokuthumela ngenqanawa	Phantsi koBubushushu be-Ambient
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya kuMhlophe oMhlophe wePowder
Ukuchongwa	I-IR: Ifana neNgcaciso yeNgcaciso
Ukujikeleziswa okuthe ngqo	+10.0°~+13.0° (C=1, Amanzi)
Ilahleko ekomisweni	<0.50%
Uthuthu lweSulfate	<0.10%
Izinto ezinxulumeneyo	Ukungcola A <0.15%
	Ubumdaka obungachazwanga eluting phambi kwePregabalin (uvavanyo A) <0.10%
	Ukungcola Okungachazwanga Eluting Emva kwe-Pregabalin (uvavanyo B ) <0.10%
	Itotali yovavanyo A kunye B <0.50%
Ubunyulu Ngu-HPLC R-Isomer	<0.15%
Iintsimbi ezinzima (njenge Pb)	<10ppm
Iikloridi (Cl)	<0.05%
Izinyibilikisi ezishiyekileyo
Isopropyl Utywala	<5000ppm
I-Ethyl Acetate	<5000ppm
Tetrahydrofuran	<250ppm
I-Isopropyl Etere	<500ppm
I-Ethanol	<1000ppm
Ubunyulu / Indlela yokuHlalutya	>99.0% (HPLC ngokomisiweyo)
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Antiepileptic Drug API

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Pregabalin iyeza lesibini lesizukulwana sesibini se-antiepileptic (AED) eyaziwa ngegama lobunikazi be-Lyrica (Pfizer, Tadworth) e-UK nase-USA, ene-γ-amino butyric structure kwisakhiwo sayo se-molecular, esinemiphumo ye-anticonvulsant. iphuhliswe ngempumelelo yinkampani iPfizer kunyango lweentlungu ze-neuropathic zeperipheral, okanye unyango lwe-adjuvant lokubanjwa kancinci.I-Pregabalin sisiyobisi se-Anticonvulsant kunye ne-antiepileptic esetyenziselwa ukunyanga isifo sokuxhuzula, intlungu ye-neuropathic, i-fibromyalgia, kunye nokuphazamiseka kokuxhalabisa ngokubanzi.Ukusetyenziswa kwayo kwisifo sokuxhuzula njengonyango olongezelelekileyo lokuxhuzula ngokuyinxenye kunye okanye ngaphandle kokwenziwa ngokubanzi okwesibini kubantu abadala.NgoDisemba 2008, i-US Food and Drug Administration (FDA) ivume i-pregabalin (igama lorhwebo "Lyrica") kunyango lwe-diabetic peripheral neuropathic pain (DPN) kunye ne-postherpetic neuralgia (PHN) ezo zombini iintlungu eziqhelekileyo ze-neuropathic.I-Pregabalin inesalathiso esivunyiweyo kwaye isetyenziswa ngokubanzi kunyango lwengxaki yokukhathazeka ngokubanzi.Uvavanyo oluninzi olungahleliwe, oluyimfama oluphindwe kabini, olulawulwa yi-placebo lufumanise ukuba i-pregabalin lunyango olusebenzayo kwizigulana ezinoxinzelelo oluqhelekileyo loxinzelelo kunye nokuphazamiseka kwentlalo.I-dose titration Unyango lwe-Epilepsy-adjunctive: 25 mg bd kwiintsuku ze-7, inyuswe nge-50 mg rhoqo ngeentsuku ze-7;ukugcinwa okuqhelekileyo kwe-300 mg yonke imihla, yahlulwe kwi-2 okanye i-3 iidosi (max. 600 mg yonke imihla, yahlulahlulwe kwi-2 okanye i-3 doses).Ingxaki yokukhathazeka ngokubanzi: I-150 mg imihla ngemihla, ihlulwe kwi-2 okanye i-3 doses, kwiintsuku ze-7, inyuswe nge-150 mg yonke imihla ye-7 (max. 600 mg imihla ngemihla, ihlulwe kwi-2 okanye i-3 doses).Ukuba uyeka i-pregabalin, kuyacetyiswa ukuba ucofe ngaphezulu kweveki enye ukunqanda ukurhoxa ngokukhawuleza.Izilumkiso Izigulana ezineemeko ezinokuthi zibangele i-encephalopathy.Izigulane ezineentliziyo ezinzima ezixinzelelekileyo.