I-Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Ubunyulu ≥98.5% (GC) iVonoprazan Fumarat Intermediate Factory

Inkcazelo emfutshane:

Igama leKhemikhali: Pyridine-3-Sulfonyl Chloride

CAS: 16133-25-8

Ubunyulu: ≥98.5% (GC)

Imbonakalo: Ulwelo olungenambala okanye oluMthubi

Umbindi weVonoprazan Fumarate (CAS: 1260141-27-2)

Umgangatho ophezulu, iMveliso yoRhwebo

E-Mail: alvin@ruifuchem.com


Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza I-Pyridine-3-Sulfonyl Chloride
Izithethantonye 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;I-Piperidine-3-Sulfonylchloride
Inombolo yeCAS 16133-25-8
Inombolo yeCAT RF-PI540
Ubume beStokhwe Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli C5H4ClNO2S
Ubunzima beMolekyuli 177.61
Uphawu Ruifu Chemical

Iinkcukacha:

Into Iinkcukacha
Imbonakalo Ulwelo olungenambala okanye oluMthubi
Ubunyulu / Indlela yokuHlalutya ≥98.5% (GC)
Indawo yokubilisa 110.0 ~ 112.0℃/2mm Hg
Ukungacoceki Okukodwa ≤0.50%
Ukungcola ngokupheleleyo ≤1.5%
Umgangatho woVavanyo Umgangatho woShishino
Ukusetyenziswa Umbindi weVonoprazan Fumarate (CAS: 1260141-27-2)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, 25kg / umphanda, okanye ngokwemfuno umthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.

Izinto eziluncedo:

1

FAQ:

Isicelo:

I-Pyridine-3-Sulfonyl Chloride (i-CAS: 16133-25-8) iphakathi kweVonoprazan Fumarate (CAS: 1260141-27-2).I-Vonoprazan Fumarate, efunyenwe kwaye yaphuhliswa ngu-Takeda no-Otsuka, yavunywa yi-PMDA yaseJapan ngoDisemba 2014, kwaye ibonakaliswe kunyango lwesilonda sesisu, isilonda se-duodenal kunye ne-reflux esophagitis.I-Vonoprazan fumarate inendlela inoveli yesenzo ebizwa ngokuba yi-potassium-competitive acid blockers, ekhuphisana ngokunqanda ukubophelela kwe-ion ye-potassium kwi-H +, i-K + -ATPase (eyaziwa ngokuba yimpompo yeproton) kwinqanaba lokugqibela lokukhutshwa kwe-asidi yesisu kwiiseli ze-parietal zesisu.I-Vonoprazan ayivimbeli umsebenzi we-Na +, i-K + -ATPase nakwizigxina ze-500 ngamaxesha aphakamileyo ngaphezu kwexabiso labo le-IC50 ngokumelene ne-gastric H +, K + -ATPase umsebenzi.Ngaphezu koko, iyeza alichatshazelwa yi-gastric secretory state, ngokungafaniyo neePPI.

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