(R)-(+)-2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst CAS 112022-83-0 Optical Purity ≥98.0%

Ubonelelo lwabavelisi;Umgangatho ophezulu kunye nexabiso loKhuphiswano

CBS Catalysts
(S)-(-)-2-Methyl-CBS-oxazaborolidine;(S)-Me-CBS Catalyst (ca. 1mol/L kwiToluene);CAS: 112022-81-8
(R)-(+)-2-Methyl-CBS-oxazaborolidine;(R)-Me-CBS Catalyst (ca. 1mol / L eToluene);CAS: 112022-83-0

CBS Catalyst
I-CBS catalyst okanye iCorey-Bakshi-Shibata catalyst yi-asymmetric catalyst ephuma kwiproline.Ifumana ukusetyenziswa okuninzi kwiimpendulo zezinto eziphilayo ezifana nokunciphisa i-CBS, i-Diels-Alder reactions kunye (3 + 2) ne-cycloadditions.I-Proline, ikhompawundi ye-chiral eyenzeka ngokwendalo, ifumaneka lula kwaye ifumaneka ngexabiso eliphantsi.Idlulisela i-stereocenter yayo kwi-catalyst ethi yona ikwazi ukuqhuba i-organic reaction ngokukhetha enye yee-enantiomers ezimbini ezinokwenzeka.Oku kukhetha kungenxa yoxinzelelo lwesteric kwimeko yotshintsho ephuhlisa i-enantiomer enye kodwa hayi enye.

I-CBS Catalysts yokuNcitshiswa kwe-Asymmetric kunye ne-Asymmetric Synthesis
I-CBS (i-Corey-Bakshi-Shibata) i-oxazaborolidine i-catalyst isetyenziswe ekunciphiseni i-asymmetric ye-prochiral ketones.Ezinye izicelo ziquka i-enantioselective synthesis ye-α-hydroxy acids, i-α-amino acids, i-C2-symmetrical ferrocenyl diols, kunye ne-propargyl alcohols.

(R) - (+) -2-Methyl-CBS-oxazaborolidine (ca. 1mol / L kwiToluene) I-CAS: 112022-83-0 ingasetyenziselwa njenge-catalyst kwi-asymmetric borane yokunciphisa i-perfluoroalkyl ketones.Ezinye izicelo ziquka i-enantioselective synthesis ye-α-hydroxy acids, i-α-amino acids, i-C2 symmetrical ferrocenyl diols, kunye ne-propargyl alcohols.Ikwasetyenziselwa ukunciphisa i-desymmetrizing ekhokelela (S) -4-hydroxycyclohexenone.Iluncedo ekuveliseni i-stereospecific motifs ezifana ne-α-hydroxy acids, i-α-amino acids, i-symmetrical ferrocenyl diols kunye ne-propargyl alcohols.

(R) - (+) -2-Methyl-CBS-oxazaborolidine (ca. 1mol / L kwiToluene) I-CAS: 112022-83-0 yi-organoboron catalyst esetyenziswa kwi-organic synthesis.Le catalyst, ephuhliswe ngu-Itsuno kunye no-Elias James Corey, iveliswa ngokufudumeza (R) - (+) -2- (diphenylhydroxymethyl) pyrrolidine kunye ne-trimethylboroxine okanye i-methylboronic acid.Sisixhobo esihle kakhulu sokudityaniswa kotywala kumlinganiselo ophezulu we-enantiomeric.Ngokuqhelekileyo, i-2-10 mol% yale catalyst isetyenziswe kunye ne-borane-tetrahydrofuran (THF), i-borane-dimethylsulfide, i-borane-N, i-N-diethylaniline, okanye i-diborane njengomthombo we-borane.Ukunciphisa i-Enantioselective usebenzisa i-chiral oxazaborolidine catalysts isetyenziswe kwi-synthesis yeziyobisi zorhwebo ezifana ne-ezetimibe kunye ne-aprepitant.