(R)-(-)-3-Quinuclidinol CAS 25333-42-0 Ubunyulu ≥99.0% Chiral Purity ≥99.0%

Inkcazelo emfutshane:

Igama leMichiza: (R)-(-)-3-Quinuclidinol

CAS: 25333-42-0

Imbonakalo: I-White okanye i-Off-White Powder

Ubunyulu: ≥99.0%

Ukucoceka kweChiral: ≥99.0%

I-API ephakathi (i-CAS: 242478-38-2) kunyango lwe-Overactive Bladder (Pollakiuria)

Enquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Iipropati zeMichiza:

Igama leMchiza	(R)-(-)-3-Quinuclidinol
Izithethantonye	(R)-3-Quinuclinol
Inombolo yeCAS	25333-42-0
Inombolo yeCAT	RF-CC117
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C7H13NO
Ubunzima beMolekyuli	127.18
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe okanye oMhlophe
Ukuchongwa kwe-RT (ngu-GC)	Thobela uMgangatho weReference
Indawo yokunyibilika	212.0~224.0℃
Ukujikeleziswa okuthe ngqo [α]_D²⁰	-40.0 ° ~ -48.0 °
Ukufuma (KF)	≤0.50%
Intsalela kwi-Ignition	≤0.50%
Ubunyulu	≥99.0%
Ukungcola ngokupheleleyo	≤1.00%
Ucoceko lweChiral	≥99.0%
I-Enantiomer	≤1.00%
Isivavanyi	98.0%～101.0% (kwisiseko esingenamanzi)
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	IiCompounds zeChiral;AbaPhakathi bamayeza

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi okhokelayo kunye nomthengisi we-(R)-(-)-3-Quinuclidinol (CAS: 25333-42-0) enomgangatho ophezulu, esetyenziswa ngokubanzi kwi-organic synthesis, i-synthesis ye-pharmaceutical intermediates kunye. I-Active Pharmaceutical Ingredient (API) synthesis.(R)-(-)-3-Quinuclidinol ingasetyenziswa njengendawo ephakathi kwi-synthesis ye-API (CAS: 242478-38-2).(I-CAS: 242478-38-2) iyeza le-antimuscarinic elisetyenziselwa ukunyanga i-bladder esebenzayo ebangela iimpawu zokuphindaphinda, ukukhawuleza, okanye ukungazinzi.(I-CAS: i-242478-38-2) i-M3 ye-muscarinic receptor antagonist eyaphuhliswa kwaye yaqaliswa kunyango lwe-bladder overactive (pollakiuria) eYurophu.Ii-receptors ze-M3 ziye zabandakanyeka kwi-neurally evoked smooth muscle contractions of the bladder, kunye ne-M2 receptors baye bakrokrelwa ukuba badlala indima ngenxa yokulawula kwabo kwi-detrusor muscle.I-synthesis ye-solifenacin ibandakanya ukulungiswa kwe-racemic 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline ngokusebenzisa i-cyclization ye-N-(2-Phenylethyl)benzamide, kunye nokusabela okulandelayo kunye ne-ethyl chloroformate kunye ne-transesterification nge (R) -3-Quinuclidinol. .Ichromatography yeChiral inika ukubekwa wedwa kwe-diastereomer efunwayo.Ngaphandle koko, i-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline inokuthi ifakwe kwisisombululo se-optical kunye (+) -i-Tartaric Acid ngaphambi kokuba unyango lwe-ethyl chloroformate kunye ne-transesterification elandelayo.