Rabeprazole Sodium CAS 117976-90-6 Ubunyulu > 99.5% (HPLC) API Factory
IRuifu Chemical Supply Rabeprazole Sodium Intermediates
Rabeprazole Sodium CAS 117976-90-6
I-Rabeprazole Hydroxy Compound CAS 675198-19-3
I-Rabeprazole Chloride Compound CAS 153259-31-5
Igama leMchiza | Rabeprazole sodium |
Izithethantonye | I-2-([4-(3-Methoxypropoxy) -3-Methylpyridin-2-yl]methylsulfinyl) -1H-Benzo[d] imidazole;Pariprazole |
Inombolo yeCAS | 117976-90-6 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C18H20N3NaO3S |
Ubunzima beMolekyuli | 381.42 |
Indawo yokunyibilika | 140.0 ~ 141.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Ikristale eMthubi kancinane ukuya kuMhlophe okanye uPowder;Hygroscopic |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Proton NMR Spectrum | Iyahambelana neSakhiwo |
I-ICP | Iqinisekisa iSodium Component |
Ukunyibilika | Inyibilika ngokupheleleyo emanzini;Inyibilika kakhulu kwi-Ethanol, iChloroform;Inyibilika kwiMethanol |
pH | 9.5~12.0 |
Ilahleko ekomisweni | <1.00% |
Iintsimbi ezinzima | <20ppm |
Izinto ezinxulumeneyo | (HPLC) |
Ukungcola A | <0.80% |
Ukungcola Okungachazwanga | <0.20% |
Ukungcola ngokupheleleyo | <1.00% |
Izinyibilikisi ezishiyekileyo | (GC) |
I-Methylene Chloride | <600ppm |
I-Ethanol | <5000ppm |
I-Isopropyl Etere | <5000ppm |
I-acetone | <5000ppm |
Umda weMicrobial | |
Ukubala kweAerobe | ≤1000CFU/g |
Ukungunda kunye namagwele Bala | ≤100CFU/g |
E. Coli | Ukungabikho ngegram nganye |
Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC, isiseko esomileyo) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | I-API ye-Anti-Ulcer |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-Rabeprazole Sodium (i-CAS: 117976-90-6) yi-proton pump inhibitor ecinezela ukuveliswa kwe-asidi yesisu esiswini.Ineendlela ezininzi zokusetyenziswa kwezonyango: ulawulo lweemeko ezibandakanya ukuveliswa kweasidi yesisu (umzekelo, iZollinger-Ellison syndrome), iimeko eziye zenziwa mandundu yi-asidi yesisu (umz. izilonda kumjelo wesisu), kunye neemeko ezibandakanya ukuvezwa ixesha elide kwi-asidi yesisu (umz. Isifo se-reflux ye-gastroesophageal symptomatic).I-Rabeprazole ikwaluncedo kunye nonyango lwe-antibiotic kunyango lwe-pathogen Helicobacter pylori, enokuthi iphumelele kwiindawo ezineasidi.Ke, iRabeprazole Sodium yi-FDA evunyiweyo kunyango lwe-GERD yeempawu kulutsha kunye nabantu abadala, ukuphilisa izilonda ze-duodenal kubantu abadala, ukupheliswa kwe-Helicobacter pylori, kunye neemeko ze-pathologic hypersecretory.I-Rabeprazole Sodium icinezela ukuveliswa kwe-asidi esiswini ngokuthintela i-gastric H +/K + ATPase (i-hydrogen-potassium adenosine triphosphatase) kwindawo eyimfihlo ye-gastric parietal cell.