Ramelteon Acrylonitrile CAS 196597-79-2 Ramelteon Intermediate Purity >98.0% (HPLC)

Inkcazelo emfutshane:

Igama leMchiza: (E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)acetonitrile

Izithethantonye: Ramelteon Acrylonitrile

CAS: 196597-79-2

Ubunyulu: >98.0% (HPLC)

Imbonakalo: Umgubo oMhlophe ukuya kumthubi

Umbindi weRamelteon (CAS: 196597-26-9)

Qhagamshelana: UGqr. Alvin Huang

Iselula/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

UMvelisi oPhambili kunye noMboneleli, abaPhakathi beRamelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-enye CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
I-Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	(E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene)acetonitrile
Izithethantonye	Ramelteon Acrylonitrile;Ukungcola kweRamelteon 6;Ukungacoceki kweRamelteon B;Ukungcola kweRamelteon Cyano;(E)-2-(6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-ylidene)i-acetonitrile;(2E)-2-(1,2,6,7-Tetrahydrocyclopenta[e][1]benzofuran-8-ylidene)i-acetonitrile;(1,2,6,7-Tetrahydro-3-oxa-as-indacen-8-ylidene)-acetonitrile
Inombolo yeCAS	196597-79-2
Inombolo yeCAT	RF2886
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C13H11NO
Ubunzima beMolekyuli	197.23
Indawo yokunyibilika	146.0 ~ 151.0℃
Indawo yokubilisa	392.1±21.0℃ kwi-760 mmHg
Indawo yokuflasha	165.0±15.9℃
Ukuxinana	1.321±0.06 g/cm3
Ikhowudi ye-HS	2932999099
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oMhlophe ukuya kumthubi
Ubunyulu / Indlela yokuHlalutya	>98.0% (HPLC)
Ilahleko ekomisweni	<1.00%
Ukungcola ngokupheleleyo	<2.00%
I-1 H NMR Spectrum	Ukungqinelana Nolwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weRamelteon (CAS: 196597-26-9)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

Ukuthenga njani?Nceda uqhagamshelaneDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

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Isicelo:

(E)-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-ylidene) i-acetonitrile (CAS: 935-56-8) iphakathi kweRamelteon (CAS: 196597 -26-9).I-Ramelteon (TAK-375) iyinoveli ye-melatonin receptor agonist ye-MT1 yabantu kunye ne-MT2 receptors kunye ne-chick forebrain melatonin receptors kunye ne-Ki ye-14 pM, i-112 pM kunye ne-23.1 pM, ngokulandelanayo.Imolekyuli ye-melatonin yatshintshwa ikakhulu ngokutshintsha initrogen yeringi ye-indole ngekhabhoni ukunika iringi ye-indane kunye nokubandakanya iqela le-5-methoxyl kwiringi ye-indole kwiringi ye-furan eyomeleleyo.Ukukhethwa kwesiphumo se-ramelteon ye-MT1 receptor ngamaxesha asibhozo ngaphezu kwe-MT2 receptor.Ngokungafaniyo ne-melatonin, isebenza ngakumbi ekuqaliseni ukulala (umsebenzi we-MT1) kunokuba ulungise isigqi se-circadian (umsebenzi we-MT2).Kubonakala ngathi isebenza ngokucace ngakumbi kune-melatonin kodwa ingasebenzi kakuhle kune-benzodiazepines njenge-hypnotic.Okubalulekileyo, eli chiza alinatyala lokulutha (ayisiyonto ilawulwayo).Ngenxa yoko, isanda kuvunywa kunyango lokungalali.