Ramelteon Intermediate CAS 196597-78-1 Ubunyulu > 98.5% (HPLC)

Inkcazelo emfutshane:

Igama: 1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-enye

Izithethantonye: 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-enye

CAS: 196597-78-1

Ubunyulu: >98.5% (HPLC)

Imbonakalo: Umgubo oqinileyo oMhlophe ukuya kumthubi

Umbindi weRamelteon (CAS: 196597-26-9)

Umgangatho ophezulu, iMveliso yoRhwebo

Qhagamshelana: UGqr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

UMvelisi oPhambili kunye noMboneleli, abaPhakathi beRamelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-enye CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
I-Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Iipropati zeMichiza:

Igama leMchiza	1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-enye
Izithethantonye	6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H)-enye;I-Ramelteon ePhakathi 1;Ramelteon I
Ukungcola	Ukungacoceki kweRamelteon A
Inombolo yeCAS	196597-78-1
Inombolo yeCAT	RF2883
Ubume beStokhwe	KwiSitokhwe, Umthamo weMveliso iiToni ezingama-20 ngenyanga
Ifomula yeemolekyuli	C11H10O2
Ubunzima beMolekyuli	174.20
Indawo yokunyibilika	133.0 ukuba 137.0℃
Indawo yokubilisa	334.2±42.0℃
Ukuxinana	1.288±0.06 g/cm3
IKlasi yeeNgozi	Iyacaphukisa
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo oqinileyo oMhlophe ukuya kumthubi
Ubunyulu / Indlela yokuHlalutya	>98.5% (HPLC)
Indawo yokunyibilika	133.0 ukuba 137.0℃
Amanzi (nguKarl Fischer)	<0.50%
Intsalela kwi-Ignition	<0.10%
Ukungcola ngokupheleleyo	<1.50%
I-1 H NMR Spectrum	Ukungqinelana Nolwakhiwo
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weRamelteon (CAS: 196597-26-9)

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma

Izinto eziluncedo:

Umthamo owaneleyo: Izixhobo ezaneleyo kunye namagcisa

Inkonzo yobuNgcali: Inkonzo enye yokuyeka ukuthenga

Ipakethe ye-OEM: Iphakheji yesiko kunye neleyibhile ekhoyo

Ukuhanjiswa ngokukhawuleza: Ukuba ngaphakathi kwesitokhwe, ukuhanjiswa kweentsuku ezintathu kuqinisekisiwe

Ubonelelo oluzinzileyo: Gcina isitokhwe esifanelekileyo

Inkxaso yobuGcisa: Isisombululo seTekhnoloji siyafumaneka

Inkonzo yesiNtu yoHlanganiso: Isuka kwiigram ukuya kwiikhilos

Umgangatho ophezulu: Kusekwe inkqubo epheleleyo yokuqinisekisa umgangatho

FAQ:

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Isicelo:

I-1,2,6,7-Tetrahydro-8H-indeno [5,4-b] furan-8-enye (CAS: 196597-78-1) isetyenziswe njengendawo ephakathi kweRamelteon (CAS: 196597-26-9) , i-nucleus yomama yokudibanisa i-Ramelteon.I-Ramelteon ngowokuqala kwiklasi entsha yee-agent zokulala ezibophelela ngokukhethekileyo kwi-MT1 kunye ne-MT2 receptors kwi-nucleus ye-suprachiasmatic (SCN), endaweni yokubopha kwi-GABA receptors.I-Ramelteon ayibonisi nakuphi na ukubophelela okuxabisekileyo kwi-GABAA receptors, ehambelana ne-anxiolytic, i-myorelaxant, kunye nemiphumo ye-amnesic.I-Ramelteon ingasetyenziselwa ukuphuthelwa, ngakumbi ukulibaziseka kokulala.I-Ramelteon ayizange iboniswe ukuba ivelise ukuxhomekeka kwaye ibonise ukuba ayinakho ukusetyenziswa kakubi, kwaye ukuhoxiswa kunye nokuphindaphinda ukulala okuqhelekileyo kunye ne-GABA modulators ayikho kwi-ramelteon.Abanye oogqirha basebenzisa i-ramelteon kunyango lwe-Delayed sleep phase syndrome.Ukunyanga ukuphuthelwa (ingxaki yokulala).Isenokusetyenziselwa ezinye iimeko njengoko kumiselwe ngugqirha wakho.I-Ramelteon yi-agonist ye-melatonin.Isebenza ngokusebenza kwi-melatonin receptors kwingqondo, ekunceda ukuba ulale.