Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester Umfanekiso okhoyo

I-Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

Inkcazelo emfutshane:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester

CAS: 1354823-36-1

Umbindi we-Remdesivir (CAS 1809249-37-3) kunyango lwe-COVID-19

Umgangatho ophezulu, iMveliso yoRhwebo

Inquiry: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo loMvelisi i-Remdesivir kunye nabaPhakathi abaNxulumeneyo nabanoMgangatho oPhezulu
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I-2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
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4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Iipropati zeMichiza:

Igama leMchiza	N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester
Izithethantonye	I-Remdesivir ePhakathi;I-Remdesivir Side Chain;I-Remdesivir p-NitroPhenoxy L-Alanine Ukungcola;Ukungcola kwe-Remdesivir 4;I-Remdesivir-002;(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl)-amino)propanoate
Inombolo yeCAS	1354823-36-1
Inombolo yeCAT	RF-PI297
Ubume beStokhwe	Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram
Ifomula yeemolekyuli	I-C21H27N2O7P
Ubunzima beMolekyuli	450.42
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Mhlophe ukuya Phantse uMhlophe
Ukuchongwa	IR, HPLC
Ilahleko ekomisweni	≤1.0%
Ukungacoceki Okukodwa	≤0.50%
Iintsimbi ezinzima	≤20ppm
Ubunyulu	≥98.0%
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	Umbindi weRemdesivir (CAS 1809249-37-3);I-COVID 19

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, eyaziwa ngokuba yi-Remdesivir Ukungcola 4) yi-phosphoramidate sidechain esetyenziselwa ukulungiswa kwe-Remdesivir (CAS . 1809249-37-3, GS-5734), elichiza eliyinoveli lophando lwe-antiviral ekuqaleni kunyango lwe-Ebola virus isifo kunye nosulelo lwentsholongwane ye-Marburg kwaye emva koko kwafunyaniswa ukuba ibonisa umsebenzi we-antiviral ngokuchasene ne-coronavirus (umz. SARS-Cov-2/ I-covid 19).Ngexesha lokuqhambuka kwesifo esitsha seCoronavirus sika-2019 (COVID-19), iRemdesivir (CAS 1809249-37-3) yenye yeemveliso zophando ezinxulumene ne-COVID-19.I-Remdesivir, ethengiswa phantsi kwegama lebhrendi iVeklury, liyeza elibanzi lokulwa neentsholongwane eliphuhliswe yinkampani yebiopharmaceutical yaseGiliyadi iSayensi.Isetyenziswa ngesitofu emithanjeni.Ngexesha lobhubhani we-COVID-19, i-Remdesivir yamkelwa okanye yagunyaziswa ukuba isetyenziswe ngokungxamisekileyo ukunyanga i-COVID-19 kumazwe amalunga nama-50.Izikhokelo ezihlaziyiweyo ezivela kuMbutho wezeMpilo weHlabathi ngoNovemba ka-2020 zibandakanya isindululo esinemiqathango ngokuchasene nokusetyenziswa kwe-Remdesivir kunyango lwe-COVID-19.