Remdesivir Intermediate CAS 1770840-43-1 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine COVID-19
Ubonelelo ngezoRhwebo loMvelisi i-Remdesivir kunye nabaPhakathi abaNxulumeneyo nabanoMgangatho oPhezulu
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4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1
Igama leMchiza | 4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine |
Izithethantonye | 7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine;I-Remdesivir-004;Ukungacoceki kwe-Remdesivir 30 |
Inombolo yeCAS | 1770840-43-1 |
Inombolo yeCAT | RF-PI304 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ukuya kumakhulu eeKilogram |
Ifomula yeemolekyuli | C6H5IN4 |
Ubunzima beMolekyuli | 260.04 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umthubi oKhanyayo ukuya kumgubo oBrown |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Ubunyulu | ≥98.0% (HPLC) |
Ilahleko ekomisweni | ≤0.50% |
Ukungacoceki Okukodwa | ≤0.50% |
Iintsimbi ezinzima | ≤20ppm |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Umbindi we-Remdesivir (CAS 1809249-37-3) |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, igubu lekhadibhodi, 25kg/Igubu, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.
I-4-Amino-7-iodopyrrolo [2,1-f][1,2,4] triazine (CAS 1770840-43-1) nguMphakathi we-Remdesivir (CAS 1809249-37-3).I-Remdesivir yikhompawundi ye-antiviral esetyenziselwa ukuthintela isenzo se-RNA polymerase.I-Remdesivir yaphandwa kuqala njengonyango lwentsholongwane ye-Ebola, kodwa inamandla okunyanga iintlobo ngeentlobo zeentsholongwane ze-RNA.Umsebenzi wayo ngokuchasene ne-coronavirus (CoV) usapho lweentsholongwane, ezinje nge-SARS-CoV kunye ne-MERS-CoV, yachazwa ngo-2017, kwaye ikwaphandwa njengonyango olunokubakho losulelo lwe-SARS-CoV-2.