I-Rimantadine Hydrochloride CAS 1501-84-4 Ubunyulu > 99.0% (GC)
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Igama leMchiza | I-Rimantadine Hydrochloride |
Izithethantonye | I-Rimantadine HCl;1-(1-Adamantyl) ethylamine Hydrochloride;1-(1-Adamntyl) ethylamine HCl;i-α-Methyl-1-Adamantanemethylamine Hydrochloride;α-Methyltricyclo [3.3.1.13,7] -Decane-1-Methanamine Hydrochloride;I-Flumadine;iMeradane;Roflual |
Inombolo yeCAS | 1501-84-4 |
Inombolo yeCAT | RF-PI2302 |
Ubume beStokhwe | Kwi-Stock, iMveliso yeMveliso ye-50 MT / ngenyanga |
Ifomula yeemolekyuli | C12H21N·HCl |
Ubunzima beMolekyuli | 215.77 |
Ukunyibilika | Inyibilika ngokukhululekileyo emanzini, iNyibilika kwi-Ethanol kunye neChloroform |
Ukunyibilika kuManzi ashushu | Phantse Ukungafihli |
Indawo yokunyibilika | 373.0~375.0℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo weCrystalline oMhlophe |
Ubunyulu / Indlela yokuHlalutya | >99.0% (GC) |
Ubunyulu(Titration ngu-AgNO3) | 98.5~101.5% |
Ilahleko ekomisweni | <0.50% |
Uthuthu lweSulfate | <0.50% |
Izinto ezinxulumeneyo | <1.00% |
Iintsimbi ezinzima | ≤0.001% |
I-Infrared Spectrum | Iyahambelana neSakhiwo |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Anti-Influenza Virus Drug |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma
I-Rimantadine Hydrochloride (i-CAS: 1501-84-4) ichiza lentsholongwane ye-anti-influenza.I-Rimantadine Hydrochloride isetyenziselwa ukuthintela okanye ukunyanga izifo ezithile zomkhuhlane (umkhuhlane) (uhlobo A) kubantu abadala (abaneminyaka eyi-17 ubudala nangaphezulu).Ikwasetyenziselwa ukuthintela usulelo lomkhuhlane (uhlobo A) ebantwaneni (ubudala obu-1 ukuya kwi-16).Inokunikezelwa yedwa okanye kunye nezithonga zomkhuhlane.I-Rimantadine Hydrochloride isetyenziselwa ukuhlanganiswa kwee-amino-acid rimantadine derivatives ezisetyenziselwa ukunyanga nokukhusela usulelo lomkhuhlane.I-Rimantadine Hydrochloride ngamachiza e-antiviral yomlomo aluncedo kwi-prophylaxis kunye nonyango losulelo lwe-influenza A virus.I-Rimantadine ine-prophylactic efficacy efaniswa ne-amantadine kodwa amandla aphantsi okubangela iziphumo ezibi.uphononongo oluyimfama kabini lwabantwana abanesifo esifana nomkhuhlane.I-37 ifumene iRimantadine iintsuku ezintlanu.Kubantwana be-37 bebonke kwiqela le-Rimantadine, i-27% ifunyenwe i-resistant yodwa xa kuthelekiswa ne-6% kwiqela elipheleleyo elifumana i-acetaminophen (P <.04).Ngaphezu koko, i-inhibitory concentration ye-rimantadine yanda kunye nexesha kwiqela le-Rimantadine (r = .4, P = .002).Xa kuthelekiswa ne-Amantadine, iRimantadine ibonakala ineprofayili yecala elisezantsi.