Rivaroxaban CAS 366789-02-8 Ubunyulu > 99.5% (HPLC) Factory API High Quality
Ubonelelo loMvelisi iRivaroxaban eNxulumeneyo nabaPhakathi:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4-(4-Aminophenyl)morpholin-3-enye CAS 438056-69-0
Rivaroxaban Intermediate CAS 446292-07-5
I-5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8
Igama leMchiza | Rivaroxaban |
Izithethantonye | (S)-Rivaroxaban;(S) -5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carbox;I-BAY 59-7939 |
Inombolo yeCAS | 366789-02-8 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | I-C19H18ClN3O5S |
Ubunzima beMolekyuli | 435.88 |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Umgubo oMhlophe okanye ophantse wamhlophe |
Isazisi A | I-infrared absorption ye-Rivaroxaban ihambelana nemigangatho yereferensi |
Isazisi B | Ixesha lokugcinwa kwencopho ephambili yesisombululo sesampulu ihambelana nesisombululo sokufaneleka kwenkqubo, njengoko ifunyenwe kwi-enantiomeric purity. |
Ucoceko lwe-Enantiomeric | I-RVX RC01: ≤0.15% |
Ukufuma (KF) | ≤0.50% |
Uthuthu lweSulfate | ≤0.10% |
Iintsimbi ezinzima | ≤20ppm |
I-Acetic Acid | ≤5000ppm |
Izinto eziyeleleneyo (HPLC) | |
I-RVX RC02 | ≤0.15% |
I-RVX RC03 | ≤0.15% |
I-RVX RC04 | ≤0.15% |
RVX RC05 | ≤0.15% |
I-RVX RC06 | ≤0.15% |
I-RVX RC07 | ≤0.15% |
I-RVX RC08 | ≤0.15% |
Nakuphi na Okunye Ukungacoceki komntu | ≤0.10% |
Ukungcola ngokupheleleyo | <0.50% |
Intsalela yezinyibilikisi (GC) | |
I-Ethanol | ≤5000ppm |
Toluene | ≤890ppm |
I-Triethylamine | ≤320ppm |
Ubunyulu / Indlela yokuHlalutya | >99.5% (HPLC) (kwisiseko se-anhydrous) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | API;Iziyobisi zeAntithrombotic;I-FXa Inhibitor |
Iphakheji: Ibhotile, ingxowa yefoyile yeAluminiyam, 25kg/Igubu lekhadibhodi, okanye ngokwemfuno yomthengi.
Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ukukhanya kunye nokufuma.
Rivaroxaban(I-CAS:366789-02-8) (Xarelto, Bayer) yi-anticoagulant yomlomo.Yinto yomlomo esebenzayo ngokuthe ngqo xa inhibitor.I-Rivaroxaban iboniswa 'unyango lwe-vein thrombosis enzulu kunye ne-pulmonary embolism, kunye nokukhusela i-thrombosis ye-deep vein thrombosis kunye ne-pulmonary embolism kubantu abadala'.Ngonyango lokuqala lwe-acute pulmonary embolism, i-dosage ephakanyisiweyo ye-rivaroxaban yi-15 mg kabini imihla ngemihla ngeentsuku zokuqala ze-21 ezilandelwa ngu-20 mg kanye ngosuku ngokuqhubekayo unyango kunye nokuthintela i-thromboembolism ye-venous ephindaphindiweyo.I-Non-Valvular Atrial Fibrillation (i-NVAF) yokukhusela i-stroke kunye ne-systemic embolism.Unyango lwe-VTE olubukhali kunye nokuthintela i-VTE ephindaphindiweyo [ye-deep vein thrombosis (DVT) kunye ne-pulmonary embolism (PE)].Ukuthintelwa kweziganeko ze-venous thromboembolic (VTE) kwi-elective total hip okanye utyando lokutshintshwa kwamadolo (THR, TKR).