(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS 85977-52-2 Ubunyulu ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate Factory

Inkcazelo emfutshane:

Igama leMichiza: (S) -1,2,3,4-1-Tetrahydro-Naphthoic Acid

CAS: 85977-52-2

Imbonakalo: Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe

Ubunyulu: ≥99.0%

I-Enantimoer Excess: ee≥99.0%

Phakathi kwePalonosetron Hydrochloride (CAS: 135729-62-3) kunyango lweCINV

E-mail: alvin@ruifuchem.com

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iimveliso ezinxulumeneyo

Iithegi zeMveliso

Inkcazo:

Ubonelelo ngezoRhwebo iPalonosetron Hydrochloride kunye nabaPhakathi abaNxulumeneyo:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
I-3-Quinuclidinone Hydrochloride CAS: 1193-65-3
I-1-Naphthoic Acid CAS: 86-55-5
I-Palonosetron Hydrochloride CAS: 135729-62-3 API

Iipropati zeMichiza:

Igama leMchiza	(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid
Izithethantonye	(1S)-1,2,3,4-Tetrahydronaphthalene-1-Carboxylic acid
Inombolo yeCAS	85977-52-2
Inombolo yeCAT	RF-CC111
Ubume beStokhwe	Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni
Ifomula yeemolekyuli	C11H12O2
Ubunzima beMolekyuli	176.21
Ukuxinana	1.186g/cm3
Indawo yokunyibilika	54.0 ~ 56.0℃
Indawo yokubilisa	342.7 ° C kwi-760 mmHg
Refractive Index	1.576
Uphawu	Ruifu Chemical

Iinkcukacha:

Into	Iinkcukacha
Imbonakalo	Umgubo weCrystalline oMhlophe okanye ophantse wamhlophe
Ucoceko lweMichiza	≥99.0%
Enantimoer Ukugqithisa	ee ≥99.0%
Ukungacoceki kwe-Isomer	≤1.0%
Ilahleko ekomisweni	≤0.50%
Nxulumanisa Into	≤1.0%
Ukufuma (KF)	≤1.0%
Ukujikeleziswa okuthe ngqo [α]_D²⁰	-59.0°~ -63.0°(C=0.3 kwi-Benzence)
Iintsimbi ezinzima	≤20ppm
Ugcino	5-8℃ Ukungangeni moya
Umgangatho woVavanyo	Umgangatho woShishino
Ukusetyenziswa	I-Palonosetron Hydrochloride (CAS: 135729-62-3) Abaphakathi

(S) -1,2,3,4-tetrahydro-1-Naphthoic Acid CAS: 85977-52-2 Indlela ye-Synthesis

Ukupakishwa kunye noGcino:

Iphakheji: Ibhotile, Igubu lekhadibhodi, 25kg / Igubu, okanye ngokwemfuno yomthengi.

Imeko yoGcino:Gcina kwizikhongozeli ezivaliweyo kwindawo epholileyo neyomileyo;Khusela ekukhanyeni, ukufuma kunye nokuhlaselwa zizinambuzane.

Izinto eziluncedo:

FAQ:

Isicelo:

I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi (S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid (CAS: 85977-52-2) kunye nomgangatho ophezulu.Yinto ephakathi ngokuqhelekileyo kwi-synthesis yePalonosetron Hydrochloride (CAS: 135729-62-3).

I-Palonosetron Hydrochloride (i-CAS: i-135729-62-3) i-noveli ye-5-HT3 ye-receptor antagonist eqaliswe njenge-agent ejoyiweyo yokuthintela isicaphucaphu kunye nokulibaziseka kunye nokuhlanza okuhambelana ne-chemotherapy yomhlaza.Inobude obude besiqingatha sobomi (~ 40 h) kunenye ekhoyo ngoku i-5-HT3 antagonists, ebonelela ngeenzuzo ezisebenzayo ekuthinteleni ukulibaziseka kwesicaphucaphu kunye nokuhlanza okwenzeka ngokuqhelekileyo emva kwe-24 h kunye neentsuku ezintandathu emva kokulawulwa kwe-chemotherapy.Nge-1,2,3,4-tetrahydro-1-Naphthoic Acid njengento yokuqala, ukuhlukana, ukuchithwa, ukunciphisa, i-cyclization, ityuwa ye-palonosetron hydrochloride granisetron.