(S)-3-Hydroxypyrrolidine Hydrochloride CAS 122536-94-1 Ucoceko ≥98.0% (GC) I-Darifenacin Hydrobromide Intermediate
Umenzi onobunyulu obuPhezulu kunye neXabiso loKhuphiswano
Ubonelelo ngezoRhwebo iDarifenacin Hydrobromide eNxulumeneyo neMiphakathi:
(S)-3-Hydroxypyrrolidine Hydrochloride CAS: 122536-94-1
(S)-α, α-Diphenyl-3-Pyrrolidineacetamide L-Tartrate CAS: 134002-26-9
(S)-2,2-Diphenyl-2-(Pyrrolidin-3-yl)acetonitrile Hydrobromide CAS: 194602-27-2
(S)-2,2-Diphenyl-2-(1-Tosylpyrrolidin-3-yl)acetonitrile CAS: 133099-09-9
2,3-Dihydrobenzofuran CAS: 496-16-2
I-2,3-Dihydrobenzofuranyl-5-Acetic Acid CAS: 69999-16-2
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I-Darifenacin Hydrobromide CAS: 133099-07-7
| Igama leMchiza | (S) -3-Hydroxypyrrolidine Hydrochloride |
| Izithethantonye | (S)-3-Hydroxypyrrolidine HCl;(S)-3-Pyrrolidinol Hydrochloride;(S)-Pyrrolidin-3-ol (Hydrochloride);(S) -Pyrrolidin-3-ol, iHCl |
| Inombolo yeCAS | 122536-94-1 |
| Inombolo yeCAT | RF-CC103 |
| Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
| Ifomula yeemolekyuli | C4H10ClNO |
| Ubunzima beMolekyuli | 123.581 |
| Indawo yokunyibilika | 104°C ukuya ku-107°C |
| Indawo yokubilisa | 108°C ukuya ku-110°C (8mmHg) |
| Ukunyibilika | I-DMSO (Kancinci), iMethanol (Kancinci) |
| Imeko yokuthumela ngenqanawa | Ithunyelwe Ngaphantsi Kweqondo Lobushushu Le-Ambient |
| Uphawu | Ruifu Chemical |
| Into | Iinkcukacha |
| Imbonakalo | Okumhlophe-kuMhlophe ukuya kumgubo omdaka weCrystalline oBrown |
| Ucoceko lweMichiza | ≥98.0% (GC) |
| Ukujikeleziswa okuthe ngqo | +6.5° ~ +8.5° (C=3 CH3OH) |
| Nakuphi na Ukungacoceki komntu | ≤0.50% |
| Ukungcola ngokupheleleyo | ≤2.0% |
| Ilahleko ekomisweni | ≤0.50% |
| Intsalela kwi-Ignition | ≤0.50% |
| Umgangatho woVavanyo | Umgangatho woShishino |
| Ukusetyenziswa | I-Darifenacin Hydrobromide (CAS: 133099-07-7) Phakathi |
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I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi we-(S)-3-Hydroxypyrrolidine Hydrochloride (CAS: 122536-94-1) enomgangatho ophezulu, esetyenziswa ngokubanzi kwi-organic synthesis, i-synthesis ye-pharmaceutical intermediates kunye ne-Active Pharmaceutical Ingredient. (API) i-synthesis.(S) -3-Hydroxypyrrolidine Hydrochloride (CAS: 122536-94-1) yeyona nto iphakathi kweDarifenacin Hydrobromide (CAS: 133099-07-7).
I-Darifenacin Hydrobromide (i-CAS: i-133099-07-7), i-esebenzayo ngomlomo, kanye ngosuku olukhethiweyo lwe-M3 ye-receptor antagonist, yaqaliswa ukunyangwa kwe-bladder esebenzayo kwizigulane ezineempawu zokuphazamiseka kwe-urinary, ukukhawuleza kunye nokuphindaphinda.Isiyobisi sithintela ngokukhethekileyo i-M3 receptor kwi-muscle detrusor ngelixa igcina i-M1 kunye ne-M2 i-receptors ekukholelwa ukuba ibandakanyeka kwinkqubo ye-nervous central kunye nomsebenzi we-cardiovascular ngokulandelanayo.Ikhompawundi yaphuhliswa kuqala yiPfizer kwaye inelayisensi eNovartis naseBayer.
