(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0 Ubunyulu ≥98.0% (HPLC) Rivaroxaban Intermediate Factory
Ubonelelo loMvelisi iRivaroxaban eNxulumeneyo nabaPhakathi:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4-(4-Aminophenyl)morpholin-3-enye CAS 438056-69-0
Rivaroxaban Intermediate CAS 446292-07-5
I-5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8
Igama leMchiza | (S)-(+)-Glycidyl Phthalimide |
Izithethantonye | (S)-Glycidyl Phthalimide;(S)-N-Glycidylphthalimide;Rivaroxaban Intermediate |
Inombolo yeCAS | 161596-47-0 |
Inombolo yeCAT | RF-PI128 |
Ubume beStokhwe | Kwi-Stock, iMveliso yoMveliso ukuya kwiiToni |
Ifomula yeemolekyuli | C11H9NO3 |
Ubunzima beMolekyuli | 203.19 |
Indawo yokunyibilika | 102℃ |
Uphawu | Ruifu Chemical |
Into | Iinkcukacha |
Imbonakalo | Mhlophe ukuya kwi-Off-White Powder |
Ukuchongwa | HPLC |
Ilahleko ekomisweni | ≤0.50% |
I-Sulfate Ash | ≤0.50% |
Ubunyulu / Indlela yokuHlalutya | ≥98.0% (HPLC) |
I-Phthalimide | ≤0.10% |
Ukungacoceki koMax omnye | ≤0.50% |
Ukungcola ngokupheleleyo | ≤2.0% |
Epichlorohydrin | ≤0.10% |
Glycidol | ≤0.10% |
Ucoceko lweChiral | I-R-isomer ≤2.0% (HPLC) |
Umgangatho woVavanyo | Umgangatho woShishino |
Ukusetyenziswa | Rivaroxaban (CAS: 366789-02-8) Phakathi |
(S)-(+)-Glycidyl Phthalimide CAS: 161596-47-0 Synthesis Route
I-Shanghai Ruifu Chemical Co., Ltd. ngumenzi ohamba phambili kunye nomthengisi (S)-(+)-Glycidyl Phthalimide (CAS: 161596-47-0) kunye nomgangatho ophezulu.Kuphakathi ngokuqhelekileyo kwi-synthesis yeRivaroxaban (CAS: 366789-02-8), kunyango lwe-Venous Thromboembolism (VTE).
I-Rivaroxaban (Xarelto; CAS: 366789-02-8) ichiza le-antithrombotic kwaye yaphuhliswa ngokubambisana phakathi kwe-German Bayer Pharmaceuticals kunye nenkampani yaseMelika Johnson.I-Rivaroxaban iboniswa kunyango lwe-thrombosis ye-vein deep kunye ne-pulmonary embolism, kunye nokuthintela i-thrombosis ye-deep vein thrombosis kunye ne-pulmonary embolism kubantu abadala.